|

Risk Stratification of MACE in Heart Failure Patients Who Undergoing CABG

RECRUITINGSponsored by Tomsk National Research Medical Center of the Russian Academy of Sciences
Actively Recruiting
SponsorTomsk National Research Medical Center of the Russian Academy of Sciences
Started2026-03-04
Est. completion2027-03
Eligibility
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07480915

Summary

PROFILE-HF is a multicenter, observational, prospective study of the clinical course and outcomes of chronic heart failure (HF) and coronary artery disease (CAD) in patients undergoing coronary artery bypass grafting (CABG). The objective of the study is to develop a method for assessing the risk of adverse cardiovascular events in patients with CAD and HF who have undergone CABG, based on preoperative GDF-15 concentrations. The study will have a 12-month follow-up period; one in-person visit is planned at the end of the follow-up period. If it is not possible to visit a doctor in person, information will be collected through telephone contact with the patient or his relative or person caring for the patient.

Eligibility

Healthy volunteers accepted
Inclusion Criteria:

* Heart Failure
* Planned coronary artery bypass grafting

Exclusion Criteria:

* Myocardial infarction
* Stroke
* Presence of implanted devices;
* Need for additional cardiac surgery other than coronary artery bypass grafting (valve repair, aneurysm);
* Severe renal dysfunction (GFR \<30 ml/min/1.73 m2);
* Severe comorbidities: active cancer; infiltrative cardiac diseases (sarcoidosis, amyloidosis, storage diseases); autoimmune diseases; acute infectious diseases and exacerbations of chronic somatic diseases.

Conditions4

CABGCAD - Coronary Artery DiseaseHeart DiseaseHeart Failure

Browse More Trials

Heart Disease trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.