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A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease

RECRUITINGSponsored by Mayo Clinic
Actively Recruiting
SponsorMayo Clinic
Started2026-04-28
Est. completion2028-05
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

The purpose of this study is to characterize pulmonary hemodynamic profiles, with a focus on PVR subtypes, in patients with left-sided valvular heart disease undergoing aortic or mitral valve intervention, and to identify patterns predicting reversibility of TR and RV dysfunction.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* ≥18 years old; AND
* Scheduled for valve procedures

Exclusion Criteria:

* Congenital heart disease (except for bicuspid aortic valve), OR
* Carcinoid heart disease, OR
* Valvular mass, OR
* Endocarditis, OR
* Any other condition that, in the opinion of the investigator, would impair their ability to complete the study

Conditions3

Heart DiseasePulmonary Vascular DiseaseValvular Heart Disease

Locations1 site

Mayo Clinic in Rochester
Rochester, Minnesota, 55905
Dr. Borlaug's Research Team(507) 255-2200

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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