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A Multicentre Observational Cross-Sectional Study of The Gastric Precancerous Epithelial Pathway Using High-Definition Endoscopy And Histopathology In India

RECRUITINGSponsored by Asian Institute of Gastroenterology, India
Actively Recruiting
SponsorAsian Institute of Gastroenterology, India
Started2026-08-01
Est. completion2028-04-01
Eligibility
Age40 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07486518

Summary

To estimate the prevalence of histologically confirmed early gastric cancer (EGC) in an Indian multicentre cohort undergoing standardised high-quality upper gastrointestinal endoscopy. EGC is defined as gastric adenocarcinoma confined to the mucosa or submucosa (T1), irrespective of lymph node status, based on histopathology.

Eligibility

Age: 40 Years+Healthy volunteers accepted
1. Adults aged ≥40 years undergoing upper gastrointestinal endoscopy for dyspepsia or other clinical indications (nonalarming and alarming symptoms both).
2. Ability to provide written informed consent.

Exclusion Criteria:

1. Known gastric malignancy.
2. Prior gastric surgery (excluding H. pylori eradication).
3. Contraindications to endoscopy or biopsy.
4. Known hereditary gastric cancer syndromes.

Conditions3

CancerEarly Gastric CancerGastric Adenocarcinoma

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