Arthrosemid vs. Steroid for the Management Knee Osteoarthritis

Summary

This study will be a randomised control trial of the use of intra-articular Arthrosamid® a novel intraarticular hydrogel vs. standard of care (steroid and local anaesthetic) for the non-operative management of knee osteoarthritis.

Eligibility

Inclusion Criteria:

* Adults
* Symptomatic single side knee pain.
* Patients with diagnosis of knee osteoarthritis radiographic Kellgren and Lawrence system OA grade II-III-IV on x ray or MRI.

Exclusion Criteria:

* Inflammatory conditions,
* Cancer,
* acute infection,
* pregnancy and breastfeeding.
* Uncontrolled diabetes mellitus,
* Joint diseases in the knee, such as rheumatoid arthritis or gout, history of knee surgery with metallic implant.
* If patient has undergone knee arthroscopy in past 6 months.
* Intra-articular injection of corticosteroids during the previous 3 months, intra-articular injection of other drugs, such as hyaluronic acid over the previous 1 year.
* Contraindications for intra-articular injection, such as thrombocytopenia, coagulopathy, articular infection of knee, impairment of immunity.

Conditions4

Interventions1

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