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Siemens Biomarker Multi-modality

RECRUITINGN/ASponsored by Duke University
Actively Recruiting
PhaseN/A
SponsorDuke University
Started2026-03
Est. completion2027-05
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

The purpose of this study is to see how well Photon Counting CT (PCCT) and ultrasound test results can find fat and scarring in the liver. They will be compared to MRI test results as the reference standard. Participants will get a regular CT scan on the PCCT scanner, plus a few extra pictures just for the study. They will also get an MRI, either on the same day or a different day, whichever is preferred. Participants will get an ultrasound on the same day as the MRI. If they have not had a hematocrit blood test in the past 24 hours, they will also receive one on the day of the CT scan.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age of 18 years or older
* Has clinically indicated CT schedule including the liver (with contrast or with and without contrast)
* Patient eligible for MR imaging
* History of chronic diffuse liver disease, steatotic liver disease, and/ or liver fibrosis
* Capable of consent

Exclusion Criteria:

* Contraindications to any of the required imaging examinations
* BMI \> 45 (based on MRI scanner capacity)

Conditions3

Fatty LiverHepatic SteatosisLiver Disease

Locations1 site

Duke University Medical Center
Durham, North Carolina, 27710
Elisabeth Luck CCRC919-684-7752mary.luck@duke.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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