The Study Tests if Preoperative Dental Screening is Superior to no Preoperative Dental Screening in Improving the Outcome of Patients Undergoing Surgical Cardiac Valve Replacement or Transcatheter Cardiac Valve Implantation.

Summary

This randomized, multicenter, open-label trial evaluates whether preoperative dental screening improves outcomes in patients undergoing surgical or transcatheter cardiac valve intervention. Participants are randomized 1:1 to preoperative dental screening or no screening. The primary outcome is time to first occurrence of all-cause death, redo-intervention of the index valve, or definite infective endocarditis within 2 years. The study uses registry-based follow-up to ensure complete outcome ascertainment.

Eligibility

Inclusion Criteria:

* Age ≥18 years
* Accepted for cardiac valve intervention
* Able to provide informed consent

Exclusion Criteria:

* Previous or ongoing infective endocarditis
* Urgent surgery
* Pain from loose tooth/teeth
* Immunosuppressive therapy (excluding corticosteroids)
* Inability to provide informed consent
* Expected loss to follow-up

Conditions3

Browse More Trials