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Implementing Low-dose ct Lung Cancer Screening in France.

RECRUITINGN/ASponsored by Assistance Publique - Hôpitaux de Paris
Actively Recruiting
PhaseN/A
SponsorAssistance Publique - Hôpitaux de Paris
Started2026-05-11
Est. completion2031-05
Eligibility
Age50 Years – 74 Years
Healthy vol.Accepted

Summary

The main objective is to estimate the detection rate of lung cancer in the population screened by low-dose chest CT scans.

Eligibility

Age: 50 Years – 74 YearsHealthy volunteers accepted
Inclusion Criteria:

* Adults aged 50-74 years
* Active or former smoker having quit less than 15 years ago
* Smoking history of at least 20 pack-years, or 15 cigarettes/day for 25 years or 10 cigarettes/day for 30 years
* Affiliation with a social security scheme
* Written informed consent prior to study participation

Temporary exclusion Criteria

* Chest CT scan performed within the previous 12 months
* Signs of respiratory infection (fever, productive cough)

Exclusion Criteria:

* Severe co-morbidities contraindicating exploration and/or management (including stereotactic surgery or radiotherapy) of lung cancers
* Poor general status (PS2 and above)
* Rest dyspnea (mMRC4)
* Cancer under active surveillance by thoracic computed tomography (CT pr PET-CT)
* Personal history of lung cancer
* Symptoms raising suspicion of lung cancer (hemoptysis, unexplained weight loss, recent onset or modification of respiratory symptoms,…)

Conditions2

CancerLung Cancer

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