A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease

Summary

This research is studying the use of a new type of standing desk in a small number of people to learn about the user experience for people with Parkinson's disease. 12 4-hour sessions will be performed to test the primary hypothesis that dynamic standing improves gait function compared to static standing and control sitting. This study has 2 phases. Phase 1 will be an open-label study and Phase 2 will be an in-lab randomized controlled trial pilot study. This is phase 1 of the study.

Eligibility

Inclusion Criteria:

* Diagnosis of Parkinson's Disease

Exclusion Criteria:

* Inability to stand or walk without an assistive device
* History of symptoms in stance that preclude safe and comfortable participation, such as dizziness and lightheadedness, orthostasis, severe symptomatic leg or back musculoskeletal pain, or medication side effects
* Any other history of medical or psychiatric comorbidity, precluding safe participation in the project.
* History of symptomatic cardiovascular or pulmonary disease
* History of active rheumatic arthritis
* History of stroke or other neurologic conditions with significant residual sensorimotor deficits
* History of disabling chronic pain syndrome requiring narcotic analgesics
* Evidence of dementia (Mini Mental State Exam (or Montreal Cognitive Assessment test) \<24 and significant impairment in activities of daily living)
* Venous ulcerative stasis or severe varicosities.
* Pregnancy as determined by urine pregnancy test prior to DXA procedure in women of childbearing potential.

Conditions2

Locations1 site

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