Explanatory Factors and Predictors of Fatigue in Patients With Sjögren's Disease: A 3-month Longitudinal Study

Summary

This prospective longitudinal study will be conducted in patients diagnosed with Sjögren's disease who are followed at the rheumatology outpatient clinic of Kahramanmaras Sutcu Imam University Medical Faculty Hospital. Demographic and clinical data will be collected from routine clinical assessments and medical records, including laboratory results obtained during standard care. Participants will undergo evaluation of pressure pain threshold using a digital algometer and complete validated questionnaires assessing fatigue, disease activity, patient-reported symptoms, anxiety and depression, pain catastrophizing, sleep quality, and physical activity level. All assessments will be performed at baseline and repeated at follow-up visits approximately 3 months later.

Eligibility

Inclusion Criteria:

* Diagnosis of Sjögren's syndrome
* Age ≥ 18 years
* Willingness to participate and provide written informed consent

Exclusion Criteria:

* Presence of severe somatic or psychiatric disorders
* Presence of malignancy
* Pregnancy
* Refusal to participate or inability to provide written informed consent

Conditions3

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