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Dexmedetomidine and Propofol for Sedation in Cataract Surgery.

RECRUITINGN/ASponsored by Saint-Joseph University
Actively Recruiting
PhaseN/A
SponsorSaint-Joseph University
Started2025-11-09
Est. completion2026-11-09
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The goal of this prospective, randomized, single-blinded is to learn if there is an ideal sedation protocol in cataract surgery in adults. The main questions it aims to answer are: * Does the combination of Dexmedetomidine and Propofol affect significantly Ramsay sedation scale, compared to Dexmedetomidine and compared to Propofol? * How does each sedation protocol affect hemodynamics? (Heart rate and blood pressure) * Are respiratory events more common in a certain group? * Is the surgeon's satisfaction similar among groups? * Are adverse effects (bradycardia, hypotension, nausea) more common in a certain group? Researchers will compare 3 sedation protocols : Dexmedetomidine versus Propofol versus the combination of these 2 drugs and to see if one protocol is overall superior to the others. Fentanyl will also be used in all 3 sedation protocols. Participants will : * Receive one of these three protocols * Be operated for one or both eyes * Monitored during the whole surgery and in the recovery room * Be evaluated by the Ramsay sedation scale by a trained Anesthesiologist or CRNA during surgery and in the recovery room Surgeons will be asked about how much they were satisfied.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Adults undergoing cataract surgery

Exclusion Criteria:

* Severe hepatic insufficiency
* Third degree AV block
* Patient refusal

Conditions11

BradycardiaCataractDexmedetomidineFentanylHeart DiseaseHemodynamicHemodynamic ChangesNausea and VomitingPropofol DosageSedation

Interventions3

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