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Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

RECRUITINGN/ASponsored by University of Alabama at Birmingham
Actively Recruiting
PhaseN/A
SponsorUniversity of Alabama at Birmingham
Started2025-09-15
Est. completion2026-08-31
Eligibility
Age18 Years – 80 Years
Healthy vol.Accepted
Locations1 site

Summary

The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help improve how the body regulates heart rate and blood pressure in people with Parkinson's Disease (PD). Problems with heart rate and blood pressure control are common and can make it harder for people to exercise or do daily activities. By using this non-invasive form of nerve stimulation and testing how it affects the body's natural responses, this study hopes to learn if taVNS could be a helpful tool to support physical therapy and improve overall function.

Eligibility

Age: 18 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Diagnosis of idiopathic PD
* Stable medication for at least 4 weeks prior to the study

Exclusion Criteria:

* Use of beta blockers
* Sustained severe hypertension (\>/= 180/110 mmHg while seated)
* Significant uncontrolled cardiac arrhythmia
* Unstable angina
* Congestive heart failure
* History of myocardial infarction
* History of seizures
* Severe cognitive impairment
* Pregnant women or women who are planning to become pregnant

Conditions2

PARKINSON DISEASE (Disorder)Parkinson's Disease

Locations1 site

Wellness, Health and Research Facility at UAB
Birmingham, Alabama, 35209
Alex Evancho205-975-5221amelgin@uab.edu

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