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Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity

RECRUITINGPhase 1Sponsored by Regeneron Pharmaceuticals
Actively Recruiting
PhasePhase 1
SponsorRegeneron Pharmaceuticals
Started2026-06-29
Est. completion2027-02-22
Eligibility
Age18 Years – 65 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT07594093

Summary

This study will test a study drug called REGN20934 to see how safe and well tolerated this drug is, as well as how the drug is processed in the body for participants with overweight or obesity. The study is looking at: * What side effects REGN20934 might cause * How much REGN20934 is in the blood at different times * If the body makes antibodies to REGN20934

Eligibility

Age: 18 Years – 65 YearsHealthy volunteers accepted
Key Inclusion Criteria:

1. Has a Body Mass Index (BMI) 25 to 35 kg/m\^2
2. Females must be of non-childbearing potential

Key Exclusion Criteria:

1. A self-reported change of body weight \>5 kg within approximately 90 days of visit 2
2. History of type 1 or type 2 diabetes
3. History of clinically significant cardiovascular, respiratory, hepatic, renal, gastrointestinal, endocrine, hematological, psychiatric, or neurological disease, as defined in the protocol

Note: Other protocol defined inclusion/exclusion criteria apply

Conditions2

DiabetesOverweight or Obesity

Interventions1

REGN20934

Locations1 site

California Clinical Trials Medical Group
Glendale, California, 91206

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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