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Frailty in Older Adults With Prostate Cancer: a Prospective Cohort Study

RECRUITINGSponsored by University of Limerick
Actively Recruiting
SponsorUniversity of Limerick
Started2026-04-23
Est. completion2027-11
Eligibility
Age65 Years+
SexMALE
Healthy vol.Accepted

Summary

Prostate cancer is the most common solid tumour cancer amongst men in Ireland, with almost 4,000 new cases diagnosed annually and a median age at diagnosis of 67 years. The incidence of frailty amongst cancer patients is high. Among patients undergoing systemic anti-cancer therapy, frailty increases the risk of treatment related toxicity, hospitalisation, and death and is associated with a poorer quality of life. This study aims to describe the demographic, clinical and frailty characteristics of men living with prostate cancer in the Mid-West of Ireland. In addition, we will assess the predictive accuracy of three frailty screening tools currently used in Irish clinical practice,G8, CFS and PRISMA 7, for predicting poorer outcomes at baseline, 6 and 12 months.

Eligibility

Age: 65 Years+Sex: MALEHealthy volunteers accepted
Inclusion Criteria:

* adults aged ≥65 years with a diagnosis of prostate cancer

Exclusion Criteria:

* Neither the patient nor the carer has sufficient proficiency in English sufficiently to complete consent or baseline assessment
* Patients will be excluded if they present outside of research nurse (RN) operational hours( 8am and 5pm Monday - Friday).
* Patients who are acutely unwell and unable to answer the questionnaire will also be excluded.

Conditions3

CancerFrailty at Older AdultsProstate Cancer

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