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Home-based Vision Rehabilitation Guided by Brain Imaging

RECRUITINGN/ASponsored by Georgetown University
Actively Recruiting
PhaseN/A
SponsorGeorgetown University
Started2026-07-01
Est. completion2030-03-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT07635329

Summary

The BRIGHT (Behavioral Rehabilitation Through Image-Guided Home-based Training) study aims to evaluate the effectiveness of image-guided, home-based perceptual training at improving visual performance in individuals with visual field loss. Using a prospective, crossover design, BRIGHT combines visual behavioral testing, neuroimaging, and a home-based intervention. It aims to 1) identify neural pathways that support training-induced visual plasticity; and 2) compare the efficacy of different types of visual training delivered in a home-based setting.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

1. At least 18 years of age.
2. Capable of providing informed consent and complying with study procedures.
3. Unilateral or bilateral focal brain damage causing visual field loss.
4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.
5. Eligible for MRI based on standard safety screening.

Exclusion Criteria:

1. Severe neurological or psychiatric conditions unrelated to the focal lesion that may interfere with study participation or data interpretation.
2. Current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.
3. Ocular disease or disorder.

Conditions10

Brain TumorCancerCortical BlindnessHemianopia HomonymousQuadrantanopiaStrokeTraumatic Brain InjuryVisual Field DefectVisual Field Defect, PeripheralVisual Field Loss

Locations1 site

Georgetown University Medical Center
Washington D.C., District of Columbia, 20057
Tina Liu, PhD202-784-9949vpplab@georgetown.edu

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