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Ex Vivo Drug Response Profiling and Outcome Prediction in Lung Adenocarcinoma

RECRUITINGSponsored by Sheba Medical Center
Actively Recruiting
SponsorSheba Medical Center
Started2023-06-14
Est. completion2028-12-01
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

This observational study evaluates if ex-vivo lung cancer drug sensitivity testing results correlate with the driver mutations found by genetic sequencing and if it can predict treatment response.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Presence of pleural effusion in patient with a diagnosis of a lung cancer or suspected to be diagnosed with lung cancer according to their CT imaging, who are in need for pleural effusion drainage due to shortness of breath, and are willing to donate effusion for ex-vivo drug sensitivity testing.
* Patient's written informed consent present.
* Ability to understand the nature of the trial and the trial related procedures and to comply with them.

Exclusion Criteria:

* negative cytology for malignancy in the last 6 months

Conditions4

CancerLung AdenocarcinomaLung CancerMalignant Pleural Effusions (Mpe)

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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