Individualized Neuro-Modulation Paired With Cerebellar Therapy

Summary

The purpose of this project is to evaluate feasibility and preliminary efficacy of pairing personalized transcranial direct current stimulation (tDCS) with individualized rehabilitation therapy in people with cerebellar damage.

Eligibility

Inclusion Criteria:

* Age 18-75 years
* Males and Females
* Disorders that predominantly affect the cerebellum: damage from stroke, tumor or degeneration (genetic or non-genetic causes, congenital hypoplasia).

Exclusion Criteria:

* Diagnoses or impairments that interfere with task execution or data interpretation.
* Heart pacemaker or other MRI-incompatible implanted metal device
* Metallic foreign body in their eye or head
* Experience with severe claustrophobia
* Experience discomfort from the MRI scan, such as excessive heating of tattoos
* Seizures or history of seizure disorder
* Alcohol or substance use disorder (self-report)
* Diagnosed history of severe psychiatric disorder such as depression, schizophrenia (self-report)
* Metallic foreign body in their eye or head (except the mouth e.g. dental fillings)
* Specific medications: tricyclic anti-depressants or neuroleptic medication
* Any medical condition (including orthopedic, pain, cardiopulmonary or other) that limits safe participation in exercise training

Conditions5

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