Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction.

Summary

This clinical study aims to evaluate the effectiveness of patient-specific 3D-printed titanium facial implants in the reconstruction and aesthetic correction of facial defects. The study will include patients presenting with congenital, traumatic, or post-surgical facial deformities requiring reconstructive intervention. Eligible participants will undergo preoperative clinical assessment and radiological imaging to design customized implants using computer-aided design (CAD) and 3D printing technology. The implants will be fabricated from medical-grade titanium and surgically placed according to standardized maxillofacial reconstructive protocols. Postoperative follow-up will assess functional outcomes, implant stability, complication rates, and aesthetic improvement over a defined observation period. Outcome evaluation will include clinical examination and patient-reported satisfaction measures. The objective of this study is to determine whether patient-specific 3D-printed titanium implants provide reliable functional restoration and improved aesthetic outcomes in facial reconstruction compared to conventional reconstructive techniques.

Eligibility

Inclusion Criteria:

* Age 18 years or older.
* Presence of facial bone defects resulting from cystic or tumoral osteolytic lesions.
* Acquired or congenital facial deformities associated with bony defects or facial asymmetry.
* Patients requiring patient-specific 3D-printed titanium implants for maxillofacial reconstruction.
* Aesthetic indications requiring custom facial implant design, including microgenia (chin retrusion).
* Ability to provide written informed consent.

Exclusion Criteria:

* Active pathological lesions at the time of enrollment.
* Age below 18 years.
* History of radiotherapy within 12 months prior to enrollment.
* Chronic untreated vitamin D deficiency.
* Uncontrolled diabetes mellitus.
* Inability or unwillingness to comply with follow-up requirements.

Conditions7

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