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Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts

RECRUITINGN/ASponsored by Benha University
Actively Recruiting
PhaseN/A
SponsorBenha University
Started2026-06-30
Est. completion2027-06
Eligibility
Age18 Years – 45 Years
SexFEMALE
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07686783

Summary

We will conduct this study to estimate the effect of laparoscopic cystectomy on ovarian reserve in endometriotic cysts versus non-endometriotic cysts.

Eligibility

Age: 18 Years – 45 YearsSex: FEMALEHealthy volunteers accepted
Inclusion Criteria:

* Female patients aged 18-45 years
* Ovarian cyst measuring 6-15 cm in diameter, confirmed by transvaginal ultrasound or MRI
* Cyst is persistent for more than 3 months if asymptomatic, OR any symptomatic cyst regardless of duration of diagnosis
* Serum anti-Müllerian hormone (AMH) level ≥ 2 ng/mL, measured within 1 month preoperatively
* Willingness to participate and provide written informed consent

Exclusion Criteria:

* Clinical or ultrasonic suspicion of ovarian malignancy
* Ovarian cyst associated with pregnancy
* Previous history of ovarian surgery
* History of pelvic irradiation or chemotherapy
* Known endocrine disorders affecting ovarian function (e.g., PCOS, premature ovarian insufficiency, thyroid dysfunction, hyperprolactinemia)
* Current use of hormonal contraceptives or hormonal therapy within 3 months prior to enrollment
* Presence of severe systemic disease that contraindicates surgery or general anesthesia
* Refusal to participate or inability to provide informed consent

Conditions6

Benign Ovarian CystCancerCystectomyEndometriosisOvarian CystsOvarian Reserve

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