LUCINAE Registry: Thoracic Cancers During Pregnancy

Summary

The LUCINAE Registry is an international, multicenter observational study collecting data on patients with thoracic cancers (including lung cancer) who are expecting a child. This includes women diagnosed during pregnancy, women who become pregnant during or after cancer, and men receiving cancer treatment at the time their partner conceives. Because thoracic cancers during pregnancy are rare, there is limited information to guide clinical decisions. This registry aims to describe patient characteristics, diagnostic approaches, treatments, and maternal and fetal outcomes. Data are collected retrospectively and prospectively from participating centers. The results of this registry are expected to improve understanding of thoracic cancers in this setting and support the development of future clinical recommendations.

Eligibility

Inclusion Criteria:

* 1\. All patients with a diagnosis of thoracic cancer (including lung cancer, mesothelioma, thymic epithelial tumors, neuroendocrine tumors or sarcoma of the thorax and other rare thoracic entities) and pregnancy (positive pregnancy test) including:

  1. Patients receiving a diagnosis of thoracic cancer during pregnancy
  2. Patients who became pregnant while having active thoracic cancer
  3. Patients previously treated for a thoracic cancer and becoming pregnant in the 5 years following end of treatment OR Men with a diagnosis of thoracic cancer (including lung cancer, mesothelioma, thymic epithelial tumors, neuroendocrine tumors or sarcoma of the thorax and other rare thoracic entities), who were undergoing active oncological treatment at the time their partner conceived their child.
* 2\. Available information about pregnancy outcomes
* 3\. Age ≥ 18 years

Exclusion Criteria:

* 1\. Patient missing data about thoracic cancer stage and diagnosis
* 2\. For retrospective patients, documented refusal to the use of clinical data for research purposes

Conditions4

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