The Value of Bowel Sounds in Evaluating Postoperative Intestinal Function Recovery in Colorectal Cancer Patients

Summary

This study enrolls patients scheduled to undergo curative surgery for colorectal cancer. Bowel sounds will be assessed preoperatively and postoperatively. By comparing intraoperative variables, the incidence of perioperative complications, reoperation rates, and postoperative outcomes-including time to first flatus, resumption of oral intake, and occurrence of intestinal obstruction-this study aims to investigate the association between perioperative bowel sounds and postoperative recovery, and provide evidence-based support for the clinical application of bowel sound monitoring. Supplementary Definitions

Eligibility

Inclusion Criteria:

* Aged 18-80 years.
* Histopathologically confirmed colorectal adenocarcinoma according to the WHO 2022 classification.
* No restriction on prior neoadjuvant or other antitumor therapies, including chemotherapy, radiotherapy, targeted therapy, or immunotherapy.
* Able to understand the study requirements and voluntarily provide written informed consent (patient and/or legally authorized representative).
* Able to communicate effectively with the investigators and willing to comply with all study procedures, including postoperative management and follow-up.

Exclusion Criteria:

* Significant organ dysfunction indicating inability to tolerate surgery or an unacceptably high perioperative risk, including:
* Severe cardiac dysfunction (NYHA Class III or IV).
* Severe hepatic dysfunction (MELD score \>12).
* Severe renal dysfunction (eGFR \<30 mL/min/1.73 m² \[CKD stage 4-5\] or end-stage renal disease requiring dialysis).
* Severe pulmonary dysfunction (resting PaO₂ \<60 mmHg on room air or respiratory failure requiring long-term oxygen therapy or mechanical ventilation).
* Participation in another clinical study within 4 weeks before enrollment or concurrent participation in another interventional clinical study.
* Emergency surgery required because of intestinal obstruction, perforation, or other acute abdominal conditions.
* Severe psychiatric disorders that would interfere with compliance with perioperative management or follow-up.
* Pregnant or breastfeeding women.
* Any other clinical or laboratory abnormality that, in the opinion of the investigator, would make the participant unsuitable for the study.

Conditions6

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