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Intraperitoneal Irrigation of Ondansteron in Combination With Lidocaine in Acute Postoperative Pain

RECRUITINGPhase 1/2Sponsored by Assiut University
Actively Recruiting
PhasePhase 1/2
SponsorAssiut University
Started2026-06-01
Est. completion2027-07-01
Eligibility
Age20 Years – 70 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07706348

Summary

This study, therefore, aimed to investigate the effect of intraperitoneal administration of ondansetron in combination to lidocaine for postoperative pain management in patients undergoing lower abdominal cancer surgery.

Eligibility

Age: 20 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria:

* ASA I-II patients
* scheduled for major lower abdominal cancer surgeries.

Exclusion Criteria:

* patients with known allergy to the study drugs,
* significant cardiac, respiratory, renal or hepatic disease,
* body mass index (BMI) ≥30 kg/m2;
* allergy to study drugs
* history of opioid use for pain management the time of enrolment or drug addiction,
* who had used benzodiazepine chronically,
* stroke or psychiatric disease that could affect the perception of pain.

Conditions2

Acue Postoperative PainCancer

Interventions1

ondansteron

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