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BRIDGE-SIC Efficacy Trial

RECRUITINGN/ASponsored by Dana-Farber Cancer Institute
Actively Recruiting
PhaseN/A
SponsorDana-Farber Cancer Institute
Started2026-08-04
Est. completion2027-06-30
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations2 sites

Summary

This is a pragmatic, prospective, randomized clinical trial to test the effectiveness of large language model (LLM)-generated serious illness conversation (SIC) summaries delivered to patients' inpatient and outpatient clinicians at the time of hospital admission on the primary outcome of days in the hospital in the next 90 days.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* DFCI Patients, defined as patients who have a DFCI medical record number.
* Admitted to an inpatient solid tumor medical oncology service at BWH (including beds that are considered to be DFCI beds within BWH)
* Age ≥ 18 years
* Mortality prediction ≥ 25%
* Admitted on a Sunday after 4pm through Friday at 4pm. These time restrictions are necessary for the workflow of this pragmatic pilot trial, as the intervention requires a staff member to send intervention emails during the work week but within \<= approximately 18 hours of admission. Accordingly, we will not enroll patients during holiday time periods (e.g., for a Monday holiday, enrollment would start on Monday at 4pm instead of Sunday at 4pm) or on days where staff absences (e.g., illness) preclude enrollment.

Exclusion Criteria:

• Patients with elective inpatient admissions (typically for planned administration of chemotherapy or other treatments)

Conditions1

Cancer

Locations2 sites

Brigham and Women's Hospital
Alexi A Wright, MD.MPH617-632-2334alexi_wright@dfci.harvard.edu
Dana Farber Cancer Institute
Alexi A Wright, MD. MPH617-632-2334Alexi_Wright@dfci.harvard.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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