Twenty-four Hour Movement Behaviors and Atherosclerotic Risk

Summary

This observational study aims to investigate how 24-hour movement behaviors are associated with atherosclerotic risk in adults with rheumatoid arthritis. These behaviors include physical activity, sedentary behavior, and sleep. The main questions it aims to answer are: * Are 24-hour movement behaviors, both individually and in combination, associated with indicators of atherosclerotic risk in adults with RA? * Do changes in 24-hour movement behaviors over 12 months relate to changes in indicators of atherosclerotic risk? Participants will: * Wear activity monitors (accelerometers) continuously for 7 days to measure physical activity, sedentary behavior, and sleep. * Answer questionnaires about their health and lifestyle. * Undergo cardiovascular assessments, body composition measurements, physical fitness tests, and blood tests to measure lipid and inflammatory profile. * Return 12 months later for follow-up assessments. The researchers hope this study will improve understanding of how daily movement behaviors influence cardiovascular health in people with rheumatoid arthritis. The findings may help inform future recommendations to promote healthier movement behaviors and improve cardiovascular risk management in this population.

Eligibility

Inclusion Criteria:

* Medical diagnosis of rheumatoid arthritis.
* Age between 18 and 65 years.
* Provide written informed consent.
* Independence in daily living activities defined as a Katz Index score of 5 or 6 points.

Exclusion Criteria:

* Acute infectious disease at the time of assessment.
* Pregnancy or breastfeeding.
* Cognitive impairment identified by the Mini-Mental State Examination according to established cutoff values.
* History of cardiovascular disease, including coronary artery disease, cerebrovascular disease, peripheral arterial disease, rheumatic heart disease, congenital heart disease, deep vein thrombosis, or pulmonary embolism.
* Use of uncontrolled vasoactive medication.
* Inability to comply with accelerometer wear requirements.
* Inability to complete study questionnaires or physical assessments.
* Invalid accelerometer data according to the study wear-time criteria.

Conditions4

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