Association Between Changes in Aortic Valve Area and Pulmonary Congestion After Transcatheter Aortic Valve Implantation

Summary

This prospective, single-center observational study aims to evaluate the relationship between changes in aortic valve hemodynamics and pulmonary congestion in patients undergoing elective transfemoral transcatheter aortic valve implantation (TAVI) for severe symptomatic aortic stenosis. Pulmonary congestion will be assessed non-invasively using lung ultrasound, with particular emphasis on B-lines, at predefined time points before and after TAVI. Changes in aortic valve area and other echocardiographic parameters will be evaluated in relation to changes in lung ultrasound findings. The primary objective is to determine the association between improvement in aortic valve area following TAVI and changes in pulmonary congestion.

Eligibility

Inclusion Criteria:

* Age ≥18 years
* Diagnosis of severe symptomatic aortic stenosis
* Scheduled for elective transfemoral transcatheter aortic valve implantation (TAVI)
* Availability of preprocedural transthoracic echocardiography
* Feasibility of lung ultrasound examination
* Provision of written informed consent

Exclusion Criteria:

* Active pneumonia
* Interstitial lung disease or pulmonary fibrosis
* Massive pleural effusion
* Acute decompensated heart failure
* Severe exacerbation of chronic obstructive pulmonary disease (COPD)
* Conditions precluding adequate thoracic ultrasound examination
* Severe mitral stenosis
* Clinically significant severe mitral regurgitation
* Development of a major complication during the procedure

Conditions2

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