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Targeted Ablation to Isolate Scar Channels Causing Ventricular Tachycardia

RECRUITINGSponsored by New York Medical College
Actively Recruiting
SponsorNew York Medical College
Started2025-03-27
Est. completion2027-12-09
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

The goal of this study is to map conducting channels within scar that cause ventricular tachycardia (VT) in patients with scar in their hearts in order to block these channels from causing VT with targeted radiofrequency ablation (cautery). Participants undergoing VT ablation mapping of these channels by pacing many sites within the scar area and determining where these channels exit the scar into normal tissue. These exits will be ablated. Immediate success and success at 1 year will be evaluated.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients with structural heart disease undergoing VT ablation

Exclusion Criteria:

1. Unable or unwilling to sign consent
2. Cardiogenic shock or NYHA Class IV heart failure and not a candidate for mechanical circulatory support for the procedure (percutaneous left ventricular assist device (LVAD), extracorporeal membrane oxygenation, or implanted LVAD)
3. Absence of substrate during initial voltage mapping

Conditions4

Heart DiseaseIschemic CardiomyopathyNonischemic CardiomyopathyVentricular Tachycardia (VT)

Locations1 site

Westchester Medical Center
Valhalla, New York, 10595
Jason T Jacobson, MD9144935314Jason.Jacobson@wmchealth.org

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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