|

The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial

RECRUITINGSponsored by Queen Mary Hospital, Hong Kong
Actively Recruiting
SponsorQueen Mary Hospital, Hong Kong
Started2026-07-01
Est. completion2026-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07820319

Summary

This study evaluates a new single-beat echocardiographic technique (TE-e', the time difference between the onset of the mitral inflow E wave and the septal e' wave on tissue Doppler imaging) for estimating left atrial pressure (LAP) in critically ill patients, comparing it against the standard two-beat method. The goal is to determine whether the faster, single-beat method gives results as reliable as the conventional method, and whether it can help identify patients with elevated left atrial pressure without an invasive procedure.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Adult patients ≥18 years admitted to the QMH Adult Intensive Care Unit (AICU)
* Requiring a transthoracic echocardiogram (TTE) as part of routine clinical care
* TE-e' obtainable by both the conventional and the novel method

Exclusion Criteria:

* Patients \<18 years of age
* Patients in atrial fibrillation
* Patients with a poor TTE acoustic window
* Patients in whom TE-e' is technically difficult to obtain or interpret by either method

Conditions5

Critical IllnessEchocardiographyElevated Left Atrial PressureHeart DiseaseLeft Ventricular Diastolic Dysfunction

Browse More Trials

Heart Disease trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.