Heart Disease Clinical Trials in Florida

152 recruiting studies across 4 cities

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Miami

All Trials in Florida

Phase

Trial	Phase	Sponsor	Dist.
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation	Phase 3	Novo Nordisk A/S	<1 mi
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM	—	Cordio Medical	<1 mi
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure	Phase 3	Boehringer Ingelheim	<1 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart	Phase 3	Boehringer Ingelheim	<1 mi
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function	Phase 3	AstraZeneca	<1 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin	Phase 3	AstraZeneca	<1 mi
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)	Phase 3	Anthos Therapeutics, Inc.	<1 mi
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)	Phase 3	Eli Lilly and Company	<1 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant	Phase 3	Eidos Therapeutics, a BridgeBio company	<1 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events	Phase 3	Amgen	<1 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS	Phase 3	DalCor Pharmaceuticals	<1 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)	—	Bristol-Myers Squibb	<1 mi
Left vs Left Randomized Clinical Trial	N/A	Baylor College of Medicine	<1 mi
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm	N/A	Kardion Inc	<1 mi
LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF	Phase 3	Tenax Therapeutics, Inc.	<1 mi
Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation	N/A	Arga Medtech SA	<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy	Phase 4	Dennis M. McNamara, MD, MS	<1 mi
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study	N/A	W.L.Gore & Associates	<1 mi
The ENCIRCLE Trial	N/A	Edwards Lifesciences	<1 mi
SELUTION 4 De Novo Small Vessel IDE Trial	N/A	M.A. Med Alliance S.A.	<1 mi
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR	N/A	Edwards Lifesciences	<1 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy	Phase 3	Lexicon Pharmaceuticals	<1 mi
Product Surveillance Registry	—	Medtronic	<1 mi
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II	N/A	Shockwave Medical, Inc.	<1 mi
Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention	Phase 4	University of Florida	<1 mi
AI Powered Mapping Technology for Identifying Arrhythmias	—	Heart Rhythm Clinical and Research Solutions, LLC	<1 mi
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)	Phase 2	Pfizer	<1 mi
CardiolRx in Recurrent Pericarditis Following IL-1 Blocker Cessation	Phase 3	Cardiol Therapeutics Inc.	<1 mi
Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day	—	Heart Rhythm Clinical and Research Solutions, LLC	<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery	Phase 3	Yale University	<1 mi
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)	Phase 2	Tectonic Therapeutic	<1 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation	Phase 3	Johns Hopkins University	<1 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment	—	Children's Oncology Group	<1 mi
Comparison of Dual Antiplatelet Therapy De-escalation by Dose Reduction Versus Switching in Patients Undergoing PCI: The Switching Antiplatelet-8 (SWAP-8) Study	Phase 4	University of Florida	<1 mi
Switching From Dual Antiplatelet Therapy to Monotherapy With Potent P2Y12 Inhibitors	Phase 4	University of Florida	<1 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.	N/A	Medtronic Cardiovascular	<1 mi
Virtual Reality for Non-cardiac Chest Pain	N/A	Mayo Clinic	<1 mi
A Precision Medicine Approach to Identify Patients Undergoing Elective PCI at Risk of Peri-PCI Myocardial Infarction	—	University of Florida	<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)	N/A	Biosense Webster, Inc.	<1 mi
The Fourth Left Atrial Appendage Occlusion Study	N/A	Hamilton Health Sciences Corporation	<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products	—	Medtronic	<1 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement	N/A	University of British Columbia	<1 mi
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study	N/A	Vektor Medical	<1 mi
Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)	Phase 2	Bristol-Myers Squibb	<1 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study	Phase 2/3	Kardigan, Inc.	<1 mi
Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension	Phase 1	Mayo Clinic	<1 mi
Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI	Phase 4	University of Florida	<1 mi
The Switching Antiplatelet-9 (SWAP-9) Study	Phase 4	University of Florida	<1 mi
TECTONIC CAD IVL IDE Study	N/A	Abbott Medical Devices	<1 mi
Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation	—	Heart Rhythm Clinical and Research Solutions, LLC	<1 mi
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity	Phase 3	Amgen	<1 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events	N/A	Cleerly, Inc.	<1 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels	N/A	Concept Medical Inc.	<1 mi
Dual Antiplatelet Therapy Escalation From Standard-dose Clopidogrel to Low-Dose Prasugrel in Patients With High Bleeding and Ischemic Risk Undergoing PCI: A Prospective, Randomized Pharmacodynamic Study (TAILOR-BLEED-2)	Phase 4	University of Florida	<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction	Phase 3	Cytokinetics	<1 mi
The CONFORM Pivotal Trial	N/A	Conformal Medical, Inc	<1 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)	—	Duke University	<1 mi
TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer	—	Mayo Clinic	<1 mi
Assessment of CCM in HF With Higher Ejection Fraction	N/A	Impulse Dynamics	<1 mi
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis	Phase 2/3	CSL Behring	<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease	—	Children's Hospital Medical Center, Cincinnati	<1 mi
Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure	N/A	Analog Device, Inc.	<1 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR	N/A	Cardiac Dimensions, Inc.	<1 mi
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy	Phase 2	Novo Nordisk A/S	<1 mi
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants	N/A	Nationwide Children's Hospital	<1 mi
Tracking Results of Ablations to Combat AF Registry Generation 2	—	AtriCure, Inc.	<1 mi
BoxX-NoAF Clinical Trial	N/A	AtriCure, Inc.	<1 mi
Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)	Phase 2	Merck Sharp & Dohme LLC	<1 mi
Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair	N/A	NeoChord	<1 mi
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma	—	Children's Oncology Group	<1 mi
ASCEND CSP IDE Study	N/A	Abbott Medical Devices	<1 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE	—	Medtronic Cardiovascular	<1 mi
A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System	N/A	Biosense Webster, Inc.	<1 mi
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure	N/A	BrioHealth Solutions, Inc.	<1 mi
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study	N/A	Ancora Heart, Inc.	<1 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity	Phase 3	SWOG Cancer Research Network	<1 mi
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention	Phase 4	Duke University	<1 mi
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure	N/A	Procyrion	<1 mi
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)	N/A	P+F Products + Features USA Inc.	<1 mi
A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD	N/A	Cleerly, Inc.	<1 mi
Ultrafiltration Versus IV Diuretics in Worsening Heart Failure	N/A	Nuwellis, Inc.	<1 mi
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk	Phase 3	Population Health Research Institute	<1 mi
Physio-Anatomy Clinical Data Collection Study	—	Gentuity, LLC	<1 mi
Abatacept in Immune Checkpoint Inhibitor Myocarditis	Phase 3	Massachusetts General Hospital	<1 mi
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry	—	SCAD Alliance	<1 mi
Chloroquine for Patients With Symptomatic Persistent Atrial Fibrillation: A Prospective Pilot Study	Phase 2	University of South Florida	<1 mi
POLARx Post Approval Study (POLARx PAS)	N/A	Boston Scientific Corporation	<1 mi
Breaking Fasts Ahead of Cardiac Caths	N/A	University of South Florida	<1 mi
A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE)	Phase 2	Genentech, Inc.	<1 mi
Encore PFO Closure Device - The PerFOrm Trial	N/A	Encore Medical Inc.	<1 mi
His-Bundle Corrective Pacing in Heart Failure	N/A	University of Rochester	<1 mi
PULSED AF Post-Approval Study	—	Medtronic Cardiac Ablation Solutions	<1 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions	N/A	Concept Medical Inc.	<1 mi
Clinical Course Of Disease In Participants With FA-CM	—	Lexeo Therapeutics	<1 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)	Phase 3	Boehringer Ingelheim	<1 mi
WIBOFA - Validation of SCT02 With ECG-App for Detection of AF	N/A	Withings	<1 mi
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III	N/A	Endotronix, Inc.	<1 mi
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis	Phase 2	Novartis Pharmaceuticals	<1 mi
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes	Phase 4	VA Office of Research and Development	<1 mi
AngelMed Guardian® System PMA Post Approval Study	—	Angel Medical Systems	<1 mi
Prevail Global Study	N/A	Medtronic Vascular	<1 mi
PREEMIE: Study for Treatment of PDA in Premature Infants	N/A	Merit Medical Systems, Inc.	<1 mi
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass	Phase 3	Octapharma	<1 mi
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System	N/A	Boston Scientific Corporation	<1 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)	N/A	University of Michigan	<1 mi
SuperSaturated Oxygen Comprehensive Observational Registry	—	TherOx	<1 mi
Single or Repeated Intravenous Administration of umbiliCAl Cord Mesenchymal sTrOmal Cells in Ischemic Cardiomyopathy	Phase 2	Roberto Bolli	<1 mi
Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart Failure	Phase 4	Sarfez Pharmaceuticals, Inc.	<1 mi
Minima Stent System Post- Approval Study (PAS)	—	Renata Medical	<1 mi
Use of Point-of-Care Ultrasound (POCUS) to Reduce Hospital Length of Stay in Patients With Heart Failure ( POCUSHF )	N/A	Florida International University	<1 mi
A Basket Study of Vosoritide in Children With Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment	Phase 2	BioMarin Pharmaceutical	<1 mi
Understanding Decentralized Trial Engagement and Clinical Impediments Through Digital Efforts (UDECIDE) Among Unrepresented Groups With Poor Cardiovascular and Cardiometabolic Health	N/A	University of Miami	<1 mi
Improving Minority Health Through Biofeedback and Stress Reduction	N/A	Amelia Saul, PhD, CTRS, BCB	<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy	Phase 3	Pierre Fabre Medicament	<1 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial	N/A	Edwards Lifesciences	4 mi
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation	Phase 2	Regeneron Pharmaceuticals	5 mi
Study of JK07 in Patients With Chronic Heart Failure	Phase 2	Salubris Biotherapeutics Inc	6 mi
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF	Phase 2	Cytokinetics	9 mi
A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque	Phase 3	NewAmsterdam Pharma	9 mi
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy	Phase 3	Alnylam Pharmaceuticals	11 mi
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients	Phase 3	Colorado Prevention Center	16 mi
RESPONDER-HF Trial	N/A	Corvia Medical	17 mi
Coronary Microvascular Disease (CMD) Registry	—	Medstar Health Research Institute	17 mi
Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR	N/A	Institut universitaire de cardiologie et de pneumologie de Québec, University Laval	17 mi
A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old.	Phase 4	Pfizer	17 mi
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy	—	Tenaya Therapeutics	17 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2	Phase 3	Mezzion Pharma Co. Ltd	17 mi
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction	Phase 3	Bayer	17 mi
ATrial Tachycardia PAcing Therapy in Congenital Heart	—	Ian Law	17 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections	Phase 3	X4 Pharmaceuticals	18 mi
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)	Phase 2/3	Merck Sharp & Dohme LLC	18 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative	—	Children's Hospital of Philadelphia	18 mi
Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block	—	The Hospital for Sick Children	18 mi
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation	Phase 3	Novo Nordisk A/S	20 mi
STOP AF First Post-Approval Study	—	Medtronic Cardiac Ablation Solutions	21 mi
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™	N/A	JenaValve Technology, Inc.	21 mi
Investigating Cardiac Health of Adults With Trauma	N/A	Nova Southeastern University	25 mi
HEMOTAG® Assessment for Short-term Outcomes of Heart Failure	N/A	Aventusoft, LLC.	27 mi
Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock	—	STAVROS G DRAKOS	27 mi
Cardiogenic Shock Working Group Registry	—	Tufts Medical Center	27 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure	N/A	Abbott Medical Devices	27 mi
Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes	N/A	3ive Labs	27 mi
Global Cardio Oncology Registry	—	The Cleveland Clinic	27 mi
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2	Phase 3	Tenax Therapeutics, Inc.	31 mi
An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis	Phase 2	Zomagen Biosciences Ltd.	37 mi
Focused Orticumab Research for Treating Inflammation in Coronary Arteries	Phase 2	Abcentra	42 mi
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia	Phase 3	Novartis Pharmaceuticals	42 mi
The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.	—	Heart Rhythm Clinical and Research Solutions, LLC	43 mi
BIOTRONIK Conduction System Pacing With the Solia Lead - Solia CSP S	N/A	Biotronik, Inc.	43 mi
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure	N/A	Boston Scientific Corporation	43 mi
Observational Study to Examine the Procedural and Outcomes of AF Ablation Assisted by STAR Apollo™ Mapping System	—	Kansas City Heart Rhythm Research Foundation	43 mi
SPHERE Per-AF Post-Approval Study	—	Medtronic Cardiac Ablation Solutions	43 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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