Heart Disease Clinical Trials in Illinois

145 recruiting studies across 1 city

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All Trials in Illinois

Phase

Trial	Phase	Sponsor	Dist.
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS	Phase 3	DalCor Pharmaceuticals	2 mi
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure	Phase 3	Boehringer Ingelheim	2 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart	Phase 3	Boehringer Ingelheim	2 mi
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients	Phase 3	Colorado Prevention Center	2 mi
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II	N/A	Shockwave Medical, Inc.	2 mi
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function	Phase 3	AstraZeneca	2 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin	Phase 3	AstraZeneca	2 mi
Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)	Phase 2	Bristol-Myers Squibb	2 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity	Phase 3	SWOG Cancer Research Network	2 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment	—	Children's Oncology Group	2 mi
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation	Phase 4	University of Illinois at Chicago	2 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease	—	Children's Hospital Medical Center, Cincinnati	2 mi
Left vs Left Randomized Clinical Trial	N/A	Baylor College of Medicine	2 mi
Prevail Global Study	N/A	Medtronic Vascular	2 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation	Phase 3	Johns Hopkins University	2 mi
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM	—	Cordio Medical	2 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study	Phase 2/3	Kardigan, Inc.	2 mi
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)	Phase 3	Eli Lilly and Company	2 mi
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR	N/A	Edwards Lifesciences	2 mi
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure	N/A	Procyrion	2 mi
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study	N/A	Ancora Heart, Inc.	2 mi
RESPONDER-HF Trial	N/A	Corvia Medical	2 mi
Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy	N/A	Rush University Medical Center	2 mi
J-Valve Transfemoral Pivotal Study	N/A	JC Medical, Inc., an affiliate of Edwards Lifesciences LLC	2 mi
Vasoactive Drugs in Intensive Care Unit	Phase 4	University of Chicago	2 mi
An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis	Phase 2	Zomagen Biosciences Ltd.	2 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant	Phase 3	Eidos Therapeutics, a BridgeBio company	2 mi
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk	Phase 3	Population Health Research Institute	2 mi
Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)	N/A	Gradient Denervation Technologies	2 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)	—	Bristol-Myers Squibb	2 mi
PARTNER 3 Trial - Aortic Valve-in-Valve	N/A	Edwards Lifesciences	2 mi
LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF	Phase 3	Tenax Therapeutics, Inc.	2 mi
BIOTRONIK Conduction System Pacing With the Solia Lead - Solia CSP S	N/A	Biotronik, Inc.	2 mi
MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry	—	CorVita Science Foundation	2 mi
Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry	—	Rush University Medical Center	2 mi
Autus Valve Pivotal Study	N/A	Autus Valve Technologies, Inc.	2 mi
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease	Phase 3	Alessandro Doria	2 mi
EFS of the DUO System for Tricuspid Regurgitation	N/A	CroiValve Limited	2 mi
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment	N/A	Columbia University	2 mi
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment	N/A	XSpline S.p.A.	2 mi
The TRICURE EFS Study	N/A	TRiCares	2 mi
Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure	N/A	University of Colorado, Denver	2 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy	Phase 4	Dennis M. McNamara, MD, MS	2 mi
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study	N/A	W.L.Gore & Associates	2 mi
The ENCIRCLE Trial	N/A	Edwards Lifesciences	2 mi
Abatacept in Immune Checkpoint Inhibitor Myocarditis	Phase 3	Massachusetts General Hospital	2 mi
Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)	N/A	Medtronic Cardiac Ablation Solutions	2 mi
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes	Phase 4	VA Office of Research and Development	2 mi
Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone	Early 1	University of Chicago	2 mi
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry	—	SCAD Alliance	2 mi
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease	Phase 1/2	Northwestern University	2 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial	N/A	Edwards Lifesciences	2 mi
A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old.	Phase 4	Pfizer	2 mi
Product Surveillance Registry	—	Medtronic	2 mi
Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future	—	International Consortium of Circulatory Assist Clinicians	2 mi
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction	—	Northwestern University	2 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women	N/A	Weill Medical College of Cornell University	2 mi
Correlation Between an Impedance Cardiography Test for Decompensation and the Development of Left Ventricular Replacement Fibrosis	N/A	Dermed Diagnostics, Inc.	2 mi
CardiolRx in Recurrent Pericarditis Following IL-1 Blocker Cessation	Phase 3	Cardiol Therapeutics Inc.	2 mi
Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation	Phase 3	University of Chicago	2 mi
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery	Phase 3	Yale University	2 mi
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)	Phase 2	Tectonic Therapeutic	2 mi
Phase 2/3 Study of KPL-387 in Recurrent Pericarditis	Phase 2/3	Kiniksa Pharmaceuticals International, plc	2 mi
Genetics of Cardiovascular and Neuromuscular Disease	—	University of Chicago	2 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.	N/A	Medtronic Cardiovascular	2 mi
Cardiac Power Output in Cardiogenic Shock Patients	Early 1	University of Chicago	2 mi
Cephea Early Feasibility Study	N/A	Abbott Medical Devices	2 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)	Phase 3	Boehringer Ingelheim	2 mi
Mobile Health Interventions to Prevent Heart Disease After Hypertensive Disorders of Pregnancy	N/A	Northwestern University	2 mi
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets	—	Northwestern University	2 mi
UIC Multi-Ethnic DCM Registry	—	University of Illinois at Chicago	2 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)	N/A	University of Michigan	2 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement	N/A	University of British Columbia	2 mi
Aspirin and Preeclampsia	Phase 4	University of Chicago	2 mi
Point-of-Care Echocardiography in Patients with Known or Suspected Aortic Stenosis	N/A	Caption Health, Inc.	2 mi
Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)	—	VDI Technologies	2 mi
Abbott Vascular Medical Device Registry	—	Abbott Medical Devices	2 mi
MANAGE-AF Registry -MANAGEment of Atrial Fibrillation Outcomes Registry (MANAGE-AF)	—	CorVita Science Foundation	2 mi
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants	N/A	Nationwide Children's Hospital	2 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2	Phase 3	Mezzion Pharma Co. Ltd	2 mi
Study of JK07 in Patients With Chronic Heart Failure	Phase 2	Salubris Biotherapeutics Inc	2 mi
Cardiogenic Shock Working Group Registry	—	Tufts Medical Center	2 mi
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy	Phase 2	Imbria Pharmaceuticals, Inc.	2 mi
iCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure	N/A	University of Illinois at Chicago	2 mi
SuperSaturated Oxygen Comprehensive Observational Registry	—	TherOx	2 mi
TECTONIC CAD IVL IDE Study	N/A	Abbott Medical Devices	2 mi
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)	N/A	XVIVO Perfusion	2 mi
LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions	Phase 4	Yale University	2 mi
Transpacific TAVR Registry	—	Duk-Woo Park, MD	2 mi
His-Bundle Corrective Pacing in Heart Failure	N/A	University of Rochester	2 mi
Minima Stent System Post- Approval Study (PAS)	—	Renata Medical	2 mi
TVMR With the INNOVALVE System Trial - Early Feasibility Study	N/A	Edwards Lifesciences	2 mi
Use of Bedside Imaging and Community Health Workers for Early Screening and Referral of Pre-symptomatic Stage B Heart Failure in the Emergency Department	N/A	Rush University Medical Center	2 mi
TEXT4HF: A Randomized Controlled Trial of a Tailored Text Messaging Intervention to Improve Self-Care in Older Adult Patients With Heart Failure	N/A	University of Illinois at Chicago	2 mi
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure	N/A	BrioHealth Solutions, Inc.	2 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative	—	Children's Hospital of Philadelphia	2 mi
CardioFocus HeartLight Post-Approval Study	N/A	CardioFocus	2 mi
Evaluation of Efficacy and Safety of THRV-1268 in Long QT Syndrome Type 2 (LQTS 2)	Phase 2/3	Thryv Therapeutics, Inc.	2 mi
Aspirin and Hemocompatibility Events in Chronic Advanced Heart Failure Patients With Assist Device	Phase 4	Columbia University	2 mi
Study of the Progression of Chronic Cardiovascular Conditions	—	Prolaio	2 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)	—	Duke University	2 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy	Phase 3	Pierre Fabre Medicament	2 mi
The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing	—	University of Chicago	2 mi
Biobank Cardiac Surgery	—	University of Chicago	6 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels	N/A	Concept Medical Inc.	11 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy	Phase 3	Lexicon Pharmaceuticals	12 mi
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves	N/A	Edwards Lifesciences	12 mi
ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System	N/A	Edwards Lifesciences	12 mi
VIZ ACCESS HCM - Multi-Site Registry	—	Viz.ai, Inc.	12 mi
Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation	—	Volta Medical	12 mi
Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)	—	McMaster University	12 mi
Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)	—	Bodyport Inc.	12 mi
Multicenter Study for the Validation of an AI-based ECG Platform for Early Cardiac Amyloidosis Diagnosis	—	Idoven 1903 S.L.	12 mi
The Fourth Left Atrial Appendage Occlusion Study	N/A	Hamilton Health Sciences Corporation	12 mi
EFS of the CardioMech MVRS	N/A	CardioMech AS	12 mi
A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD	N/A	Cleerly, Inc.	12 mi
Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation	—	Heart Rhythm Clinical and Research Solutions, LLC	12 mi
Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure	N/A	McMaster University	12 mi
Pivotal Study for the Cardiac Performance System (CPS)	—	Sensydia Corporation	12 mi
The NODE-202 Study (Study of Etripamil Nasal Spray in Pediatric Patients)	Phase 2	Milestone Pharmaceuticals Inc.	13 mi
SELUTION 4 De Novo Small Vessel IDE Trial	N/A	M.A. Med Alliance S.A.	13 mi
Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR	Phase 3	Wake Forest University Health Sciences	13 mi
The JenaValve ALIGN-AR LVAD Registry	N/A	JenaValve Technology, Inc.	13 mi
Association of Near Infrared Spectroscopy With Interstage Outcomes	N/A	Advocate Hospital System	13 mi
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)	Phase 3	Anthos Therapeutics, Inc.	14 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events	Phase 3	Amgen	14 mi
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)	N/A	P+F Products + Features USA Inc.	16 mi
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions	N/A	Boston Scientific Corporation	16 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)	N/A	Biosense Webster, Inc.	16 mi
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry	—	University of Colorado, Denver	16 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events	N/A	Cleerly, Inc.	16 mi
A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation	N/A	Boston Scientific Corporation	16 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure	N/A	Abbott Medical Devices	17 mi
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III	N/A	Endotronix, Inc.	18 mi
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation	Phase 3	Novo Nordisk A/S	20 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR	N/A	Cardiac Dimensions, Inc.	20 mi
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2	Phase 3	Tenax Therapeutics, Inc.	21 mi
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity	Phase 3	Amgen	21 mi
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)	Phase 2	Pfizer	21 mi
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation	Phase 3	Novo Nordisk A/S	21 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction	Phase 3	Cytokinetics	23 mi
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure	N/A	Boston Scientific Corporation	27 mi
The CONFORM Pivotal Trial	N/A	Conformal Medical, Inc	27 mi
Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure	—	Endotronix, Inc.	27 mi
Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial	N/A	University of Minnesota	27 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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