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Heart Disease Clinical Trials in North Carolina

131 recruiting studies across 2 cities

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All Trials in North Carolina

Phase
Trial Phase Dist.
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney FunctionPhase 3<1 mi
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)Phase 3<1 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With DapagliflozinPhase 3<1 mi
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart FailurePhase 4<1 mi
J-Valve Transfemoral Pivotal StudyN/A<1 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)<1 mi
Left vs Left Randomized Clinical TrialN/A<1 mi
PARTNER 3 Trial - Aortic Valve-in-ValveN/A<1 mi
LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEFPhase 3<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum CardiomyopathyPhase 4<1 mi
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval StudyN/A<1 mi
The ENCIRCLE TrialN/A<1 mi
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry<1 mi
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing DialysisPhase 2/3<1 mi
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina IIN/A<1 mi
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic ValvesN/A<1 mi
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With CardiomyopathyPhase 3<1 mi
Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and RecoveryPhase 3<1 mi
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary LesionsN/A<1 mi
AltaValve Pivotal TrialN/A<1 mi
Cephea Early Feasibility StudyN/A<1 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)Phase 3<1 mi
EFS of the CardioMech MVRSN/A<1 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve ReplacementN/A<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease<1 mi
Pediatric Prehospital Airway Resuscitation TrialN/A<1 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2Phase 3<1 mi
Reducing Risk for Infective EndocarditisN/A<1 mi
Study of JK07 in Patients With Chronic Heart FailurePhase 2<1 mi
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart FailureN/A<1 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart FailureN/A<1 mi
CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)N/A<1 mi
CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) StudyN/A<1 mi
The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States StudyN/A<1 mi
Assessment of CCM in HF With Higher Ejection FractionN/A<1 mi
A Basket Study of Vosoritide in Children With Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone TreatmentPhase 2<1 mi
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular InterventionPhase 4<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and ChemotherapyPhase 3<1 mi
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and InflammationPhase 3<1 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the HeartPhase 3<1 mi
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)Phase 3<1 mi
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular RiskPhase 3<1 mi
SELUTION 4 De Novo Small Vessel IDE TrialN/A<1 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABGPhase 3<1 mi
Product Surveillance Registry<1 mi
HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)N/A<1 mi
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart FailurePhase 3<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products<1 mi
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF StudyN/A<1 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small VesselsN/A<1 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery LesionsN/A<1 mi
FORWARD CAD IDE StudyN/A<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection FractionPhase 38 mi
A Phase 2 Study of CRD-4730 in CPVTPhase 211 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic CardiomyopathyPhase 311 mi
Personalized Environment and Genes Study15 mi
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)Phase 221 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled StudyPhase 2/321 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular EventsN/A21 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)21 mi
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and IIIN/A21 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR VariantPhase 321 mi
Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)N/A21 mi
Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)Phase 221 mi
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - WomenPhase 321 mi
Ventripoint Single Ventricle StudyN/A21 mi
Medtronic Cardiac Surgery PMCF Registry21 mi
Autus Valve Pivotal StudyN/A21 mi
Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)21 mi
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy AssessmentN/A21 mi
Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart RecipientsPhase 221 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious InfectionsPhase 321 mi
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)N/A21 mi
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomesPhase 421 mi
Rare Glycogen Storage Diseases Natural History Study21 mi
Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection FractionN/A21 mi
A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old.Phase 421 mi
Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice ProvidersN/A21 mi
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)Phase 121 mi
Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study21 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in WomenN/A21 mi
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - MinoritiesPhase 321 mi
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary BypassPhase 321 mi
PK/PD of Digoxin in Infants With SVHDPhase 1/221 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.N/A21 mi
Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis21 mi
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection FractionPhase 121 mi
Cord Clamping Among Neonates With Congenital Heart DiseaseN/A21 mi
Early Feasibility Study of the NORM™ System in Heart Failure Patients (FUTURE-HFII)N/A21 mi
Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)Phase 221 mi
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)N/A21 mi
The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) TrialPhase 421 mi
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionN/A21 mi
CTSN Embolic Protection TrialN/A21 mi
Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac SurgeryPhase 121 mi
A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE)Phase 221 mi
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting21 mi
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)N/A21 mi
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp SystemPhase 221 mi
Sex Differences in Barriers and Participation in Physical Activity During and Following Cardiac Rehabilitation21 mi
LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic ConditionsPhase 421 mi
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and ObesityPhase 321 mi
PKP2-ACM Natural History Study21 mi
BiVACOR® Total Artificial Heart Early Feasibility StudyN/A21 mi
PULSED AF Post-Approval Study21 mi
PRIMARY Ancillary SubstudyN/A21 mi
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular HypertrophyPhase 221 mi
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart FailureN/A21 mi
Supporting Health in Veterans With Heart FailureN/A21 mi
Cardiac Outcomes With Near-Complete Estrogen DeprivationN/A21 mi
Long-term Safety and Efficacy of Odevixibat in Patients With Alagille SyndromePhase 321 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACSPhase 323 mi
Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation23 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular EventsPhase 324 mi
A Study of Modified Release RTN-001 In Patients With Uncontrolled HypertensionPhase 224 mi
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease25 mi
Physical Activity and Community EmPOWERment ProjectN/A25 mi
Abatacept in Immune Checkpoint Inhibitor MyocarditisPhase 325 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical TrialN/A25 mi
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and InflammationPhase 325 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial FibrillationPhase 325 mi
The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR StudyPhase 225 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)N/A25 mi
Optimal Ventilation for Cardiac ArrestN/A25 mi
Healthy Living Anson StudyN/A25 mi
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry25 mi
Depression, Aging, Stress and Heart Health StudyN/A25 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative25 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac ToxicityPhase 345 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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