Heart Disease Clinical Trials in Philadelphia, PA

156 recruiting studies within 50 miles

Phase

Trial	Phase	Sponsor	Dist.
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS	Phase 3	DalCor Pharmaceuticals	<1 mi
Assessment of CCM in HF With Higher Ejection Fraction	N/A	Impulse Dynamics	<1 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study	Phase 2/3	Kardigan, Inc.	<1 mi
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation	Phase 3	Novo Nordisk A/S	<1 mi
RESPONDER-HF Trial	N/A	Corvia Medical	<1 mi
A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old.	Phase 4	Pfizer	<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery	Phase 3	Yale University	<1 mi
Optimal Ventilation for Cardiac Arrest	N/A	Children's Hospital of Philadelphia	<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease	—	Children's Hospital Medical Center, Cincinnati	<1 mi
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy	—	Tenaya Therapeutics	<1 mi
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma	—	Children's Oncology Group	<1 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2	Phase 3	Mezzion Pharma Co. Ltd	<1 mi
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction	Phase 3	Bayer	<1 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative	—	Children's Hospital of Philadelphia	<1 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events	Phase 3	Amgen	<1 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)	Phase 3	Boehringer Ingelheim	<1 mi
Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation	—	Heart Rhythm Clinical and Research Solutions, LLC	<1 mi
Left vs Left Randomized Clinical Trial	N/A	Baylor College of Medicine	<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products	—	Medtronic	<1 mi
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)	Phase 3	Eli Lilly and Company	<1 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial	N/A	Edwards Lifesciences	<1 mi
Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery	N/A	Unity Health Toronto	<1 mi
Fontan Fitness Trial	N/A	Children's Hospital of Philadelphia	<1 mi
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure	Phase 4	AstraZeneca	<1 mi
VIZ ACCESS HCM - Multi-Site Registry	—	Viz.ai, Inc.	<1 mi
Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation	Early 1	University of Pennsylvania	<1 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant	Phase 3	Eidos Therapeutics, a BridgeBio company	<1 mi
Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst	—	Boston Medical Center	<1 mi
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	—	Columbia University	<1 mi
The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.	—	Heart Rhythm Clinical and Research Solutions, LLC	<1 mi
Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children	—	University of Pennsylvania	<1 mi
PARTNER 3 Trial - Aortic Valve-in-Valve	N/A	Edwards Lifesciences	<1 mi
Autus Valve Pivotal Study	N/A	Autus Valve Technologies, Inc.	<1 mi
An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System	N/A	HighLife SAS	<1 mi
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis	Phase 2	Novartis Pharmaceuticals	<1 mi
Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL Amyloidosis	Phase 3	Life Molecular Imaging GmbH	<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy	Phase 4	Dennis M. McNamara, MD, MS	<1 mi
Prospective 4D CTA of BAV Competence	—	University of Pennsylvania	<1 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections	Phase 3	X4 Pharmaceuticals	<1 mi
Abatacept in Immune Checkpoint Inhibitor Myocarditis	Phase 3	Massachusetts General Hospital	<1 mi
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients	Phase 4	University of Rochester	<1 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG	Phase 3	Icahn School of Medicine at Mount Sinai	<1 mi
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry	—	SCAD Alliance	<1 mi
Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants	—	University of Pennsylvania	<1 mi
Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)	—	McMaster University	<1 mi
Penn Medicine Healthy Heart	N/A	University of Pennsylvania	<1 mi
A Study of SGT-212 Gene Therapy in Friedreich's Ataxia	Phase 1	Solid Biosciences Inc.	<1 mi
MASA Valve Early Feasibility Study	N/A	PECA Labs	<1 mi
TEE 3D RV Assessment for SAVR, Mini AVR, and TAVR	—	Thomas Jefferson University	<1 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy	Phase 3	Lexicon Pharmaceuticals	<1 mi
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)	Phase 1	Rocket Pharmaceuticals Inc.	<1 mi
AI Powered Mapping Technology for Identifying Arrhythmias	—	Heart Rhythm Clinical and Research Solutions, LLC	<1 mi
Valved Graft PMCF Study	—	Abbott Medical Devices	<1 mi
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease	Phase 2	Rocket Pharmaceuticals Inc.	<1 mi
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM	Phase 1/2	Tenaya Therapeutics	<1 mi
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy	Phase 3	Alnylam Pharmaceuticals	<1 mi
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction	—	Northwestern University	<1 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women	N/A	Weill Medical College of Cornell University	<1 mi
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation	Phase 3	Novo Nordisk A/S	<1 mi
EluPro Antibiotic-Eluting BioEnvelope Registry	—	Elutia Inc.	<1 mi
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)	Phase 2	Tectonic Therapeutic	<1 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation	Phase 3	Johns Hopkins University	<1 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment	—	Children's Oncology Group	<1 mi
Clinical Study of the inQB8 TTVR System	N/A	inQB8 Medical Technologies, LLC	<1 mi
Calculating Wall Shear Stress in Infant Pulmonary Veins	Phase 1	Children's Hospital of Philadelphia	<1 mi
Randomized Assessment of TcMS for VT Storm	N/A	University of Pennsylvania	<1 mi
Beta-blocker Administration for Cardiomyocyte Division	Phase 1	Weill Medical College of Cornell University	<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)	N/A	Biosense Webster, Inc.	<1 mi
The Fourth Left Atrial Appendage Occlusion Study	N/A	Hamilton Health Sciences Corporation	<1 mi
Intra-aortic Balloon Counterpulsation (IABC) Compliance	—	Thomas Jefferson University	<1 mi
Cord Clamping Among Neonates With Congenital Heart Disease	N/A	Carl Backes, MD	<1 mi
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets	—	Northwestern University	<1 mi
Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure	Phase 4	Electrophysiology Research Foundation	<1 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)	N/A	University of Michigan	<1 mi
The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)	N/A	Temple University	<1 mi
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function	Phase 3	AstraZeneca	<1 mi
Low Dose Vasopressin vs Phenylephrine in Cardiac Surgery	Phase 4	Thomas Jefferson University	<1 mi
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study	N/A	Vektor Medical	<1 mi
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)	N/A	Annetine Gelijns	<1 mi
Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)	N/A	Varian, a Siemens Healthineers Company	<1 mi
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants	N/A	Nationwide Children's Hospital	<1 mi
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)	Phase 2/3	Merck Sharp & Dohme LLC	<1 mi
Resuscitative TEE Collaborative Registry	—	University of Pennsylvania	<1 mi
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™	N/A	JenaValve Technology, Inc.	<1 mi
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction	N/A	Edwards Lifesciences	<1 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin	Phase 3	AstraZeneca	<1 mi
CTSN Embolic Protection Trial	N/A	Icahn School of Medicine at Mount Sinai	<1 mi
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation	N/A	University of Pennsylvania	<1 mi
Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression	—	University of Pennsylvania	<1 mi
A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE)	Phase 2	Genentech, Inc.	<1 mi
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting	—	Corcym S.r.l	<1 mi
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure	N/A	Procyrion	<1 mi
Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients	Phase 2	University of Pennsylvania	<1 mi
Fibrosis and the Fontan	Phase 1/2	Children's Hospital of Philadelphia	<1 mi
ASCEND CSP IDE Study	N/A	Abbott Medical Devices	<1 mi
His-Bundle Corrective Pacing in Heart Failure	N/A	University of Rochester	<1 mi
TVMR With the INNOVALVE System Trial - Early Feasibility Study	N/A	Edwards Lifesciences	<1 mi
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures	—	Boston Children's Hospital	<1 mi
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry	—	University of Colorado, Denver	<1 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR	N/A	Cardiac Dimensions, Inc.	<1 mi
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study	N/A	Ancora Heart, Inc.	<1 mi
Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT	N/A	Thermedical, Inc.	<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction	Phase 3	Cytokinetics	<1 mi
Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure	N/A	McMaster University	<1 mi
Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)	N/A	Innoventric LTD	<1 mi
Pivotal Study for the Cardiac Performance System (CPS)	—	Sensydia Corporation	<1 mi
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)	Phase 1	Solid Biosciences Inc.	<1 mi
Foundational Programs to Combat Clinician Stress	N/A	Lancaster General Hospital	<1 mi
PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial	N/A	Thomas Jefferson University	<1 mi
Cholate Clearance in Fontan and Heart Failure	—	HepQuant, LLC	<1 mi
Long-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US)	—	Mirum Pharmaceuticals, Inc.	<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy	Phase 3	Pierre Fabre Medicament	<1 mi
Product Surveillance Registry	—	Medtronic	3 mi
Prevail Global Study	N/A	Medtronic Vascular	3 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement	N/A	University of British Columbia	3 mi
Lymphatic System Stimulation in Heart Failure	N/A	Rutgers, The State University of New Jersey	3 mi
The HEARTFELT Study	N/A	Heartfelt Technologies	5 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity	Phase 3	SWOG Cancer Research Network	7 mi
The CONFORM Pivotal Trial	N/A	Conformal Medical, Inc	7 mi
Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)	Phase 2	Merck Sharp & Dohme LLC	7 mi
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR	N/A	Edwards Lifesciences	7 mi
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2	Phase 3	Tenax Therapeutics, Inc.	7 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.	N/A	Medtronic Cardiovascular	7 mi
Medtronic Terminate AF Study	N/A	Medtronic Cardiac Surgery	7 mi
ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System	N/A	Edwards Lifesciences	7 mi
Trisol System EFS Study	N/A	Trisol Medical	7 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE	—	Medtronic Cardiovascular	7 mi
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention	Phase 4	Duke University	7 mi
Ultrafiltration Versus IV Diuretics in Worsening Heart Failure	N/A	Nuwellis, Inc.	12 mi
Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)	Phase 2	Bristol-Myers Squibb	12 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure	N/A	Abbott Medical Devices	12 mi
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy	Phase 2	Novo Nordisk A/S	12 mi
Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure	—	Impulse Dynamics	14 mi
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System	N/A	Boston Scientific Corporation	14 mi
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity	Phase 3	Amgen	14 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events	N/A	Cleerly, Inc.	14 mi
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)	Phase 3	Anthos Therapeutics, Inc.	16 mi
BIOTRONIK Conduction System Pacing With the Solia Lead - Solia CSP S	N/A	Biotronik, Inc.	18 mi
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis	Phase 2/3	CSL Behring	25 mi
A Basket Study of Vosoritide in Children With Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment	Phase 2	BioMarin Pharmaceutical	25 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)	—	Duke University	25 mi
Tezspire Cardiac Events PASS	—	AstraZeneca	25 mi
SPHERE Per-AF Post-Approval Study	—	Medtronic Cardiac Ablation Solutions	25 mi
PULSED AF Post-Approval Study	—	Medtronic Cardiac Ablation Solutions	25 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart	Phase 3	Boehringer Ingelheim	26 mi
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm	N/A	Kardion Inc	31 mi
Left Ventricular Structural Predictors of Sudden Cardiac Death	—	Johns Hopkins University	36 mi
A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD	N/A	Cleerly, Inc.	42 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels	N/A	Concept Medical Inc.	45 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions	N/A	Concept Medical Inc.	45 mi
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure	Phase 3	Boehringer Ingelheim	46 mi
Heart Attack Research Program- Imaging Study	—	NYU Langone Health	48 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)	—	Bristol-Myers Squibb	48 mi
Women's Heart Attack Research Program: Stress Ancillary Study	N/A	NYU Langone Health	48 mi
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study	N/A	W.L.Gore & Associates	48 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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