|

Heart Disease Clinical Trials in Philadelphia, PA

152 recruiting studies within 50 miles

Phase
Trial Phase Dist.
Assessment of CCM in HF With Higher Ejection FractionN/A<1 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACSPhase 3<1 mi
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and ObesityPhase 3<1 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled StudyPhase 2/3<1 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative<1 mi
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic DysfunctionPhase 3<1 mi
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and RecoveryPhase 3<1 mi
A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone TreatmentPhase 2<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease<1 mi
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy<1 mi
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic DysfunctionPhase 3<1 mi
Optimal Ventilation for Cardiac ArrestN/A<1 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2Phase 3<1 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular EventsPhase 3<1 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)Phase 3<1 mi
Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias<1 mi
Product Surveillance Registry<1 mi
Left vs Left Randomized Clinical TrialN/A<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products<1 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical TrialN/A<1 mi
Transfusion Requirements in Younger Patients Undergoing Cardiac SurgeryN/A<1 mi
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure PatientsPhase 3<1 mi
Prevail Global StudyN/A<1 mi
Randomized Assessment of TcMS for VT StormN/A<1 mi
Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VTN/A<1 mi
ViewFlex X ICE First-in-Human Study<1 mi
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting<1 mi
Valved Graft PMCF Study<1 mi
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionN/A<1 mi
A Study of SGT-212 Gene Therapy in Friedreich's AtaxiaPhase 1<1 mi
A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava IsolationN/A<1 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR VariantPhase 3<1 mi
Resuscitative TEE Collaborative Registry<1 mi
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight InfantsN/A<1 mi
His-Bundle Corrective Pacing in Heart FailureN/A<1 mi
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™N/A<1 mi
Prospective 4D CTA of BAV Competence<1 mi
CTSN Embolic Protection TrialN/A<1 mi
An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement SystemN/A<1 mi
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)Phase 1<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection FractionPhase 3<1 mi
Clinical Study of the inQB8 TTVR System (The MonarQ Study)N/A<1 mi
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)Phase 3<1 mi
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography TrialPhase 3<1 mi
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device ImplantationN/A<1 mi
Cord Clamping Among Neonates With Congenital Heart DiseaseN/A<1 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious InfectionsPhase 3<1 mi
Abatacept in Immune Checkpoint Inhibitor MyocarditisPhase 3<1 mi
Intra-aortic Balloon Counterpulsation (IABC) Compliance<1 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With DapagliflozinPhase 3<1 mi
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)Phase 3<1 mi
Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)N/A<1 mi
Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)N/A<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)N/A<1 mi
The Fourth Left Atrial Appendage Occlusion StudyN/A<1 mi
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF StudyN/A<1 mi
PARTNER 3 Trial - Aortic Valve-in-ValveN/A<1 mi
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney FunctionPhase 3<1 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMRN/A<1 mi
Pivotal Study for the Cardiac Performance System (CPS)<1 mi
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCMPhase 1/2<1 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment<1 mi
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry<1 mi
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets<1 mi
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic CardiomyopathyPhase 2<1 mi
A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial FibrillationN/A<1 mi
A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD StudyN/A<1 mi
Calculating Wall Shear Stress in Infant Pulmonary VeinsPhase 1<1 mi
Abbott Structural Heart Device Registry<1 mi
MASA Valve Early Feasibility StudyN/A<1 mi
Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants<1 mi
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)<1 mi
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve StenosisPhase 2<1 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial FibrillationPhase 3<1 mi
A Gene Therapy Study of RP-A501 in Male Patients With Danon DiseasePhase 2<1 mi
TVMR With the INNOVALVE System Trial - Early Feasibility StudyN/A<1 mi
Fontan Fitness TrialN/A<1 mi
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart FailureN/A<1 mi
Penn Medicine Healthy HeartN/A<1 mi
Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)<1 mi
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction<1 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)N/A<1 mi
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With CardiomyopathyPhase 3<1 mi
Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant RecipientsPhase 2<1 mi
Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression<1 mi
Beta-blocker Administration for Cardiomyocyte DivisionPhase 1<1 mi
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)N/A<1 mi
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart FailurePhase 4<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum CardiomyopathyPhase 4<1 mi
Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst<1 mi
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)Phase 2/3<1 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic CardiomyopathyPhase 3<1 mi
Quantifying New Heart Muscle CellsN/A<1 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABGPhase 3<1 mi
Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) StudyN/A<1 mi
Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive ProcedureN/A<1 mi
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)Phase 1<1 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart FailureN/A<1 mi
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and InflammationPhase 3<1 mi
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) PatientsPhase 4<1 mi
Characterization of Cardiac Electrophysiological Effects of Autonomic NeuromodulationEarly 1<1 mi
The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.<1 mi
Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children<1 mi
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)N/A<1 mi
Synchronized Diaphragmatic Stimulation in Symptomatic Heart FailureN/A<1 mi
Improving Heart Health in Individuals With SCI Using Home-Based Virtual GamingN/A<1 mi
VIZ ACCESS HCM - Multi-Site Registry<1 mi
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart FailureN/A<1 mi
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures<1 mi
Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)N/A<1 mi
The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)N/A<1 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in WomenN/A<1 mi
Foundational Programs to Combat Clinician StressN/A<1 mi
PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID TrialN/A<1 mi
Long-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US)<1 mi
Cholate Clearance in Fontan and Heart Failure<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and ChemotherapyPhase 3<1 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve ReplacementN/A3 mi
The HEARTFELT StudyN/A5 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac ToxicityPhase 37 mi
The CONFORM Pivotal TrialN/A7 mi
Medtronic Terminate AF StudyN/A7 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE7 mi
ELEVATE-HFpEF Clinical StudyN/A7 mi
Trisol System EFS StudyN/A7 mi
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2Phase 37 mi
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVRN/A7 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.N/A7 mi
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular InterventionPhase 47 mi
Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)Phase 212 mi
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular HypertrophyPhase 212 mi
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)Phase 313 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular EventsN/A14 mi
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation SystemN/A14 mi
Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure14 mi
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and ObesityPhase 314 mi
BIOTRONIK Investigation of the LivIQ Leadless Pacemaker SystemN/A18 mi
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)Phase 2/325 mi
Tezspire Cardiac Events PASS25 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)25 mi
PULSED AF Post-Approval Study25 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the HeartPhase 326 mi
CCM OPEN HF Registry31 mi
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEmN/A31 mi
Left Ventricular Structural Predictors of Sudden Cardiac Death36 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small VesselsN/A45 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery LesionsN/A45 mi
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart FailurePhase 346 mi
Behavioral Exposure for Introceptive Tolerance RCTN/A46 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)48 mi
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval StudyN/A48 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.