Heart Disease Clinical Trials in Philadelphia, PA

153 recruiting studies within 50 miles

Phase

Trial	Phase	Sponsor	Dist.
Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children	—	University of Pennsylvania	<1 mi
PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial	N/A	Thomas Jefferson University	<1 mi
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure	Phase 4	AstraZeneca	<1 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment	—	Children's Oncology Group	<1 mi
Abatacept in Immune Checkpoint Inhibitor Myocarditis	Phase 3	Massachusetts General Hospital	<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy	Phase 3	Pierre Fabre Medicament	<1 mi
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	—	Columbia University	<1 mi
Foundational Programs to Combat Clinician Stress	N/A	Lancaster General Hospital	<1 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant	Phase 3	Eidos Therapeutics, a BridgeBio company	<1 mi
VIZ ACCESS HCM - Multi-Site Registry	—	Viz.ai, Inc.	<1 mi
Calculating Wall Shear Stress in Infant Pulmonary Veins	Phase 1	Children's Hospital of Philadelphia	<1 mi
Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression	—	University of Pennsylvania	<1 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure	N/A	Abbott Medical Devices	<1 mi
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease	Phase 2	Rocket Pharmaceuticals Inc.	<1 mi
Quantifying New Heart Muscle Cells	N/A	Weill Medical College of Cornell University	<1 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2	Phase 3	Mezzion Pharma Co. Ltd	<1 mi
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation	N/A	University of Pennsylvania	<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction	Phase 3	Cytokinetics	<1 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)	Phase 3	Boehringer Ingelheim	<1 mi
The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.	—	Heart Rhythm Clinical and Research Solutions, LLC	<1 mi
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures	—	Boston Children's Hospital	<1 mi
A Study of SGT-212 Gene Therapy in Friedreich's Ataxia	Phase 1	Solid Biosciences Inc.	<1 mi
Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation	Early 1	University of Pennsylvania	<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)	N/A	Biosense Webster, Inc.	<1 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events	Phase 3	Amgen	<1 mi
Abbott Structural Heart Device Registry	—	Abbott Medical Devices	<1 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative	—	Children's Hospital of Philadelphia	<1 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections	Phase 3	X4 Pharmaceuticals	<1 mi
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)	Phase 1	Solid Biosciences Inc.	<1 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation	Phase 3	Johns Hopkins University	<1 mi
Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants	—	University of Pennsylvania	<1 mi
Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure	N/A	McMaster University	<1 mi
A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment	Phase 2	BioMarin Pharmaceutical	<1 mi
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction	Phase 3	Bayer	<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy	Phase 4	Dennis M. McNamara, MD, MS	<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products	—	Medtronic	<1 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS	Phase 3	DalCor Pharmaceuticals	<1 mi
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy	Phase 2	Imbria Pharmaceuticals, Inc.	<1 mi
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients	Phase 3	Colorado Prevention Center	<1 mi
Product Surveillance Registry	—	Medtronic	<1 mi
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™	N/A	JenaValve Technology, Inc.	<1 mi
Intra-aortic Balloon Counterpulsation (IABC) Compliance	—	Thomas Jefferson University	<1 mi
Beta-blocker Administration for Cardiomyocyte Division	Phase 1	Weill Medical College of Cornell University	<1 mi
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy	Phase 3	Alnylam Pharmaceuticals	<1 mi
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction	—	Northwestern University	<1 mi
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease	Phase 1	Verve Therapeutics, Inc.	<1 mi
The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)	N/A	Temple University	<1 mi
PARTNER 3 Trial - Aortic Valve-in-Valve	N/A	Edwards Lifesciences	<1 mi
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting	—	Corcym S.r.l	<1 mi
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function	Phase 3	AstraZeneca	<1 mi
Penn Medicine Healthy Heart	N/A	University of Pennsylvania	<1 mi
Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)	N/A	Varian, a Siemens Healthineers Company	<1 mi
Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients	Phase 2	University of Pennsylvania	<1 mi
Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT	N/A	Thermedical, Inc.	<1 mi
ViewFlex X ICE First-in-Human Study	—	Abbott Medical Devices	<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery	Phase 3	Yale University	<1 mi
Prevail Global Study	N/A	Medtronic Vascular	<1 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women	N/A	Weill Medical College of Cornell University	<1 mi
MASA Valve Early Feasibility Study	N/A	PECA Labs	<1 mi
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure	N/A	Procyrion	<1 mi
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets	—	Northwestern University	<1 mi
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)	Phase 1	Rocket Pharmaceuticals Inc.	<1 mi
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis	Phase 2	Novartis Pharmaceuticals	<1 mi
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma	—	Children's Oncology Group	<1 mi
Clinical Study of the inQB8 TTVR System (The MonarQ Study)	N/A	inQB8 Medical Technologies, LLC	<1 mi
Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery	N/A	Unity Health Toronto	<1 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study	Phase 2/3	Kardigan, Inc.	<1 mi
Resuscitative TEE Collaborative Registry	—	University of Pennsylvania	<1 mi
Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst	—	Boston Medical Center	<1 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG	Phase 3	Icahn School of Medicine at Mount Sinai	<1 mi
Pivotal Study for the Cardiac Performance System (CPS)	—	Sensydia Corporation	<1 mi
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)	Phase 2/3	Merck Sharp & Dohme LLC	<1 mi
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy	—	Tenaya Therapeutics	<1 mi
His-Bundle Corrective Pacing in Heart Failure	N/A	University of Rochester	<1 mi
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure	N/A	Boston Scientific Corporation	<1 mi
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM	Phase 1/2	Tenaya Therapeutics	<1 mi
Prospective 4D CTA of BAV Competence	—	University of Pennsylvania	<1 mi
TVMR With the INNOVALVE System Trial - Early Feasibility Study	N/A	Edwards Lifesciences	<1 mi
Cord Clamping Among Neonates With Congenital Heart Disease	N/A	Carl Backes, MD	<1 mi
Virtue® SAB in the Treatment of Coronary ISR Trial	N/A	Orchestra BioMed, Inc	<1 mi
The Fourth Left Atrial Appendage Occlusion Study	N/A	Hamilton Health Sciences Corporation	<1 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)	N/A	University of Michigan	<1 mi
Left vs Left Randomized Clinical Trial	N/A	Baylor College of Medicine	<1 mi
Valved Graft PMCF Study	—	Abbott Medical Devices	<1 mi
Long-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US)	—	Mirum Pharmaceuticals, Inc.	<1 mi
Fontan Fitness Trial	N/A	Children's Hospital of Philadelphia	<1 mi
Randomized Assessment of TcMS for VT Storm	N/A	University of Pennsylvania	<1 mi
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants	N/A	Nationwide Children's Hospital	<1 mi
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction	N/A	Edwards Lifesciences	<1 mi
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study	N/A	Vektor Medical	<1 mi
Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)	N/A	Innoventric LTD	<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease	—	Children's Hospital Medical Center, Cincinnati	<1 mi
Assessment of CCM in HF With Higher Ejection Fraction	N/A	Impulse Dynamics	<1 mi
Optimal Ventilation for Cardiac Arrest	N/A	Children's Hospital of Philadelphia	<1 mi
Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)	—	McMaster University	<1 mi
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry	—	University of Colorado, Denver	<1 mi
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients	Phase 4	University of Rochester	<1 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR	N/A	Cardiac Dimensions, Inc.	<1 mi
Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias	—	Heart Rhythm Clinical and Research Solutions, LLC	<1 mi
An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System	N/A	HighLife SAS	<1 mi
CTSN Embolic Protection Trial	N/A	Icahn School of Medicine at Mount Sinai	<1 mi
Cholate Clearance in Fontan and Heart Failure	—	HepQuant, LLC	<1 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin	Phase 3	AstraZeneca	<1 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial	N/A	Edwards Lifesciences	<1 mi
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)	Phase 3	Intellia Therapeutics	<1 mi
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial	Phase 3	Amgen	<1 mi
Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure	N/A	VisCardia Inc.	<1 mi
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)	Phase 3	Novartis Pharmaceuticals	<1 mi
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study	N/A	Carelon Research	<1 mi
Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)	N/A	Supira Medical	<1 mi
A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation	N/A	Biosense Webster, Inc.	<1 mi
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction	Phase 3	Bayer	<1 mi
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity	Phase 3	Novo Nordisk A/S	<1 mi
Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) Study	N/A	AtaCor Medical, Inc.	<1 mi
Improving Heart Health in Individuals With SCI Using Home-Based Virtual Gaming	N/A	Drexel University	<1 mi
Removing Surrogates Uncertainty to Reduce Fear and Anxiety After Cardiac Events - Kids	N/A	Children's Hospital of Philadelphia	<1 mi
PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis	Phase 3	Duke University	<1 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement	N/A	University of British Columbia	3 mi
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation	Phase 2	Novartis Pharmaceuticals	3 mi
The HEARTFELT Study	N/A	Heartfelt Technologies	5 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity	Phase 3	SWOG Cancer Research Network	7 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE	—	Medtronic Cardiovascular	7 mi
Medtronic Terminate AF Study	N/A	Medtronic Cardiac Surgery	7 mi
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2	Phase 3	Tenax Therapeutics, Inc.	7 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.	N/A	Medtronic Cardiovascular	7 mi
ELEVATE-HFpEF Clinical Study	N/A	Medtronic Cardiac Rhythm and Heart Failure	7 mi
Trisol System EFS Study	N/A	Trisol Medical	7 mi
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR	N/A	Edwards Lifesciences	7 mi
The CONFORM Pivotal Trial	N/A	Conformal Medical, Inc	7 mi
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention	Phase 4	Duke University	7 mi
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy	Phase 2	Novo Nordisk A/S	12 mi
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)	Phase 3	Anthos Therapeutics, Inc.	13 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events	N/A	Cleerly, Inc.	14 mi
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity	Phase 3	Amgen	14 mi
Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure	—	Impulse Dynamics	14 mi
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System	N/A	Boston Scientific Corporation	14 mi
BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System	N/A	Biotronik, Inc.	18 mi
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)	Phase 2/3	CSL Behring	25 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)	—	Duke University	25 mi
PULSED AF Post-Approval Study	—	Medtronic Cardiac Ablation Solutions	25 mi
Tezspire Cardiac Events PASS	—	AstraZeneca	25 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart	Phase 3	Boehringer Ingelheim	26 mi
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm	N/A	Kardion Inc	31 mi
CCM OPEN HF Registry	—	Impulse Dynamics	31 mi
Left Ventricular Structural Predictors of Sudden Cardiac Death	—	Johns Hopkins University	36 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions	N/A	Concept Medical Inc.	45 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels	N/A	Concept Medical Inc.	45 mi
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure	Phase 3	Boehringer Ingelheim	46 mi
Behavioral Exposure for Introceptive Tolerance RCT	N/A	Rutgers, The State University of New Jersey	46 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)	—	Bristol-Myers Squibb	48 mi
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study	N/A	W.L.Gore & Associates	48 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.