Heart Disease Clinical Trials in Raleigh, NC

105 recruiting studies within 50 miles

Phase

Trial	Phase	Sponsor	Dist.
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)	Phase 3	Eli Lilly and Company	<1 mi
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk	Phase 3	Population Health Research Institute	<1 mi
PARTNER 3 Trial - Aortic Valve-in-Valve	N/A	Edwards Lifesciences	<1 mi
SELUTION 4 De Novo Small Vessel IDE Trial	N/A	M.A. Med Alliance S.A.	<1 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG	Phase 3	Icahn School of Medicine at Mount Sinai	<1 mi
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis	Phase 2/3	CSL Behring	<1 mi
Product Surveillance Registry	—	Medtronic	<1 mi
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation	Phase 3	Novo Nordisk A/S	<1 mi
HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry	—	University of Kansas Medical Center	<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)	N/A	Biosense Webster, Inc.	<1 mi
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure	Phase 3	Boehringer Ingelheim	<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products	—	Medtronic	<1 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart	Phase 3	Boehringer Ingelheim	<1 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin	Phase 3	AstraZeneca	<1 mi
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study	N/A	Ancora Heart, Inc.	<1 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels	N/A	Concept Medical Inc.	<1 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions	N/A	Concept Medical Inc.	<1 mi
FORWARD CAD IDE Study	N/A	Shockwave Medical, Inc.	<1 mi
Study of JK07 in Patients With Chronic Heart Failure	Phase 2	Salubris Biotherapeutics Inc	8 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction	Phase 3	Cytokinetics	8 mi
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)	Phase 3	Anthos Therapeutics, Inc.	8 mi
A Phase 2 Study of CRD-4730 in CPVT	Phase 2	Cardurion Pharmaceuticals, Inc.	11 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy	Phase 3	Lexicon Pharmaceuticals	11 mi
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention	Phase 4	Duke University	11 mi
Personalized Environment and Genes Study	—	National Institute of Environmental Health Sciences (NIEHS)	15 mi
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery	Phase 3	Yale University	21 mi
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function	Phase 3	AstraZeneca	21 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events	N/A	Cleerly, Inc.	21 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)	—	Duke University	21 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy	Phase 3	Pierre Fabre Medicament	21 mi
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III	N/A	Endotronix, Inc.	21 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant	Phase 3	Eidos Therapeutics, a BridgeBio company	21 mi
Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)	N/A	Gradient Denervation Technologies	21 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)	—	Bristol-Myers Squibb	21 mi
Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)	Phase 2	Merck Sharp & Dohme LLC	21 mi
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women	Phase 3	Weill Medical College of Cornell University	21 mi
Ventripoint Single Ventricle Study	N/A	Duke University	21 mi
LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF	Phase 3	Tenax Therapeutics, Inc.	21 mi
Medtronic Cardiac Surgery PMCF Registry	—	Medtronic Cardiac Surgery	21 mi
Autus Valve Pivotal Study	N/A	Autus Valve Technologies, Inc.	21 mi
Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)	—	Duke University	21 mi
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment	N/A	XSpline S.p.A.	21 mi
Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients	Phase 2	Baylor Research Institute	21 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections	Phase 3	X4 Pharmaceuticals	21 mi
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)	N/A	P+F Products + Features USA Inc.	21 mi
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes	Phase 4	VA Office of Research and Development	21 mi
Rare Glycogen Storage Diseases Natural History Study	—	Duke University	21 mi
Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction	N/A	Duke University	21 mi
A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old.	Phase 4	Pfizer	21 mi
Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers	N/A	Duke University	21 mi
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)	Phase 1	Rocket Pharmaceuticals Inc.	21 mi
Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study	—	Abbott Medical Devices	21 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women	N/A	Weill Medical College of Cornell University	21 mi
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities	Phase 3	Weill Medical College of Cornell University	21 mi
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)	Phase 2	Tectonic Therapeutic	21 mi
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass	Phase 3	Octapharma	21 mi
PK/PD of Digoxin in Infants With SVHD	Phase 1/2	Duke University	21 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.	N/A	Medtronic Cardiovascular	21 mi
Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis	—	Duke University	21 mi
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction	Phase 1	Sardocor Corp.	21 mi
Cord Clamping Among Neonates With Congenital Heart Disease	N/A	Carl Backes, MD	21 mi
Early Feasibility Study of the NORM™ System in Heart Failure Patients (FUTURE-HFII)	N/A	Foundry Innovation & Research 1, Limited (FIRE1)	21 mi
Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)	Phase 2	Bristol-Myers Squibb	21 mi
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)	N/A	Annetine Gelijns	21 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study	Phase 2/3	Kardigan, Inc.	21 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease	—	Children's Hospital Medical Center, Cincinnati	21 mi
The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial	Phase 4	VA Office of Research and Development	21 mi
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction	N/A	Edwards Lifesciences	21 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2	Phase 3	Mezzion Pharma Co. Ltd	21 mi
CTSN Embolic Protection Trial	N/A	Icahn School of Medicine at Mount Sinai	21 mi
Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery	Phase 1	Pacira Pharmaceuticals, Inc	21 mi
A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE)	Phase 2	Genentech, Inc.	21 mi
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting	—	Corcym S.r.l	21 mi
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)	N/A	XVIVO Perfusion	21 mi
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure	N/A	Procyrion	21 mi
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System	Phase 2	Stanford University	21 mi
Sex Differences in Barriers and Participation in Physical Activity During and Following Cardiac Rehabilitation	—	Duke University	21 mi
LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions	Phase 4	Yale University	21 mi
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity	Phase 3	Amgen	21 mi
PKP2-ACM Natural History Study	—	Rocket Pharmaceuticals Inc.	21 mi
BiVACOR® Total Artificial Heart Early Feasibility Study	N/A	BiVACOR Inc.	21 mi
PULSED AF Post-Approval Study	—	Medtronic Cardiac Ablation Solutions	21 mi
PRIMARY Ancillary Substudy	N/A	Annetine Gelijns	21 mi
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy	Phase 2	Novo Nordisk A/S	21 mi
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure	N/A	BrioHealth Solutions, Inc.	21 mi
Supporting Health in Veterans With Heart Failure	N/A	Florida State University	21 mi
Cardiac Outcomes With Near-Complete Estrogen Deprivation	N/A	Duke University	21 mi
Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome	Phase 3	Albireo, an Ipsen Company	21 mi
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	—	University of North Carolina, Chapel Hill	25 mi
Left vs Left Randomized Clinical Trial	N/A	Baylor College of Medicine	25 mi
Physical Activity and Community EmPOWERment Project	N/A	University of North Carolina, Chapel Hill	25 mi
Abatacept in Immune Checkpoint Inhibitor Myocarditis	Phase 3	Massachusetts General Hospital	25 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial	N/A	Edwards Lifesciences	25 mi
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation	Phase 3	Novo Nordisk A/S	25 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation	Phase 3	Johns Hopkins University	25 mi
The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study	Phase 2	University of North Carolina, Chapel Hill	25 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)	N/A	University of Michigan	25 mi
Optimal Ventilation for Cardiac Arrest	N/A	Children's Hospital of Philadelphia	25 mi
Healthy Living Anson Study	N/A	University of North Carolina, Chapel Hill	25 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure	N/A	Abbott Medical Devices	25 mi
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry	—	University of Colorado, Denver	25 mi
Depression, Aging, Stress and Heart Health Study	N/A	University of North Carolina, Chapel Hill	25 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative	—	Children's Hospital of Philadelphia	25 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS	Phase 3	DalCor Pharmaceuticals	37 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity	Phase 3	SWOG Cancer Research Network	45 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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