Heart Disease Clinical Trials in San Jose, CA

153 recruiting studies within 50 miles

Phase

Trial	Phase	Sponsor	Dist.
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis	Phase 2/3	CSL Behring	<1 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity	Phase 3	SWOG Cancer Research Network	<1 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)	N/A	University of Michigan	4 mi
TriClip CED RWE Study	—	Abbott Medical Devices	4 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction	Phase 3	Cytokinetics	4 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.	N/A	Medtronic Cardiovascular	11 mi
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation	Phase 2	Regeneron Pharmaceuticals	16 mi
Mechanisms of Semaglutide Therapy in Heart Failure Patients	Phase 1/2	University Medical Centre Ljubljana	16 mi
Large Language Models To Improve the Quality of Care of Cardiology Patients	N/A	Stanford University	16 mi
Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries	Phase 2/3	Stanford University	16 mi
J-Valve Transfemoral Pivotal Study	N/A	JC Medical, Inc., an affiliate of Edwards Lifesciences LLC	16 mi
Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease	N/A	Duk-Woo Park, MD	16 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)	—	Bristol-Myers Squibb	16 mi
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)	Phase 3	NYU Langone Health	16 mi
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis	Phase 2	Novartis Pharmaceuticals	16 mi
Physio-Anatomy Clinical Data Collection Study	—	Gentuity, LLC	16 mi
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes	Phase 4	VA Office of Research and Development	16 mi
A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old.	Phase 4	Pfizer	16 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment	—	Children's Oncology Group	16 mi
Randomized Trial of SGLT2i in Heart Transplant Recipients	Phase 4	VA Office of Research and Development	16 mi
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation	Phase 3	Novo Nordisk A/S	16 mi
Re-Energize Fontan	N/A	Stanford University	16 mi
Medtronic Terminate AF Study	N/A	Medtronic Cardiac Surgery	16 mi
Cord Clamping Among Neonates With Congenital Heart Disease	N/A	Carl Backes, MD	16 mi
Evaluating Pulse Oximetry Bias in Children With Darker Skin Pigmentation	—	Stanford University	16 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement	N/A	University of British Columbia	16 mi
Optimal Ventilation for Cardiac Arrest	N/A	Children's Hospital of Philadelphia	16 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease	—	Children's Hospital Medical Center, Cincinnati	16 mi
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants	N/A	Nationwide Children's Hospital	16 mi
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System	Phase 2	Stanford University	16 mi
OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels	—	Inova Health Care Services	16 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events	N/A	Cleerly, Inc.	16 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative	—	Children's Hospital of Philadelphia	16 mi
Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery	—	Stanford University	16 mi
A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation	N/A	Boston Scientific Corporation	16 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)	—	Duke University	16 mi
Product Surveillance Registry	—	Medtronic	17 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products	—	Medtronic	17 mi
Mobile Application for Patient Engagement and Physician-Directed Remote Management of Heart Failure	N/A	University of Michigan	17 mi
Machine Learning in Atrial Fibrillation	—	Stanford University	17 mi
Heart Attack Research Program- Imaging Study	—	NYU Langone Health	17 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant	Phase 3	Eidos Therapeutics, a BridgeBio company	17 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS	Phase 3	DalCor Pharmaceuticals	17 mi
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	—	Columbia University	17 mi
Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)	Phase 2	Merck Sharp & Dohme LLC	17 mi
Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair	N/A	NeoChord	17 mi
PARTNER 3 Trial - Aortic Valve-in-Valve	N/A	Edwards Lifesciences	17 mi
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease	Phase 3	Alessandro Doria	17 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy	Phase 4	Dennis M. McNamara, MD, MS	17 mi
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR	N/A	Edwards Lifesciences	17 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG	Phase 3	Icahn School of Medicine at Mount Sinai	17 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial	N/A	Edwards Lifesciences	17 mi
REHAB Fontan Failure: A Trial of Cardiac Rehabilitation	N/A	Stanford University	17 mi
Prevail Global Study	N/A	Medtronic Vascular	17 mi
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves	N/A	Edwards Lifesciences	17 mi
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery	Phase 3	Yale University	17 mi
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass	Phase 3	Octapharma	17 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation	Phase 3	Johns Hopkins University	17 mi
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions	N/A	Boston Scientific Corporation	17 mi
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System	N/A	Boston Scientific Corporation	17 mi
COMparison of Physiological Algorithms for Real-time Evaluation of Atrial Fibrillation	—	Stanford University	17 mi
The Dynamics of Human Atrial Fibrillation	—	Stanford University	17 mi
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)	N/A	Annetine Gelijns	17 mi
Study of JK07 in Patients With Chronic Heart Failure	Phase 2	Salubris Biotherapeutics Inc	17 mi
A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE)	Phase 2	Genentech, Inc.	17 mi
Evaluation of Patients With Non-obstructive Coronary Arteries	—	Stanford University	17 mi
Transpacific TAVR Registry	—	Duk-Woo Park, MD	17 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE	—	Medtronic Cardiovascular	17 mi
PRIMARY Ancillary Substudy	N/A	Annetine Gelijns	17 mi
Identifying Markers of Exercise Training in Heart Failure	N/A	Stanford University	17 mi
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study	N/A	Starlight Cardiovascular Inc	17 mi
Stress Management Program	N/A	Stanford University	17 mi
Assessment of CCM in HF With Higher Ejection Fraction	N/A	Impulse Dynamics	22 mi
A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM	—	Lexeo Therapeutics	22 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR	N/A	Cardiac Dimensions, Inc.	22 mi
CardioMEMS HF System Coverage with Evidence Development Study	—	Abbott Medical Devices	22 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin	Phase 3	AstraZeneca	25 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)	N/A	Biosense Webster, Inc.	31 mi
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™	N/A	JenaValve Technology, Inc.	31 mi
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure	N/A	Boston Scientific Corporation	39 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events	Phase 3	Amgen	41 mi
Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure	N/A	University of Colorado, Denver	41 mi
Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation	—	Heart Rhythm Clinical and Research Solutions, LLC	41 mi
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III	N/A	Endotronix, Inc.	42 mi
Ultrafiltration Versus IV Diuretics in Worsening Heart Failure	N/A	Nuwellis, Inc.	42 mi
Virtual Care Strategies to Improve Participation in Cardiac Rehabilitation Among Veterans	Phase 2	VA Office of Research and Development	42 mi
Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst	—	Boston Medical Center	42 mi
PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest	Phase 2	University of California, San Francisco	42 mi
LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF	Phase 3	Tenax Therapeutics, Inc.	42 mi
The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery	Phase 4	University of California, San Francisco	42 mi
Effect of Fetal Aortic Valvuloplasty on Outcomes	—	Queen Silvia Children's Hospital, Gothenburg, Sweden	42 mi
Gauging Outcomes of Total Milk Ingestion on Lipid and gControl	N/A	University of California, San Francisco	42 mi
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF	Phase 2	Cytokinetics	42 mi
Supportive Training After Cardiac Rehabilitation Including Virtual Engagement	N/A	University of California, San Francisco	42 mi
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study	N/A	W.L.Gore & Associates	42 mi
The ENCIRCLE Trial	N/A	Edwards Lifesciences	42 mi
Full-Avoidance vs. Permissive/Regulated Drinking & Outcomes On Fibrillation	N/A	University of California, San Francisco	42 mi
Digitally Rendered Interventions And Knowledge To Limit Ethanol-Associated Atrial Fibrillation Severity	N/A	University of California, San Francisco	42 mi
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)	N/A	P+F Products + Features USA Inc.	42 mi
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients	Phase 4	University of Rochester	42 mi
The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).	N/A	Mayra Guerrero	42 mi
A Phase 2 Study of CRD-4730 in CPVT	Phase 2	Cardurion Pharmaceuticals, Inc.	42 mi
Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR	N/A	Institut universitaire de cardiologie et de pneumologie de Québec, University Laval	42 mi
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry	—	SCAD Alliance	42 mi
Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease	N/A	Population Health Research Institute	42 mi
Improving Congenital Heart Disease Care	N/A	University of California, San Francisco	42 mi
Exercise Intolerance in Non-obstructive Hypertrophic Cardiomyopathy	N/A	University of California, San Francisco	42 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy	Phase 3	Lexicon Pharmaceuticals	42 mi
Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation	N/A	University of California, San Francisco	42 mi
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II	N/A	Shockwave Medical, Inc.	42 mi
Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future	—	International Consortium of Circulatory Assist Clinicians	42 mi
Evaluation of A Clinical Diagnostic Test for CRDS	N/A	Population Health Research Institute	42 mi
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia	Phase 3	Novartis Pharmaceuticals	42 mi
Voice Analysis to Detect Pulmonary Arterial Pressure Changes in Heart Failure	—	Noah Labs	42 mi
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM	Phase 1/2	Tenaya Therapeutics	42 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women	N/A	Weill Medical College of Cornell University	42 mi
buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest	Phase 2	University of California, San Francisco	42 mi
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation	N/A	University of California, San Francisco	42 mi
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)	Phase 2	Tectonic Therapeutic	42 mi
Phase 2/3 Study of KPL-387 in Recurrent Pericarditis	Phase 2/3	Kiniksa Pharmaceuticals International, plc	42 mi
Developing a Digital Aid to Improve ICD Decisions	N/A	Stanford University	42 mi
AltaValve Pivotal Trial	N/A	4C Medical Technologies, Inc.	42 mi
Metformin for Pulmonary Hypertension HFpEF	Phase 2	University of California, San Francisco	42 mi
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM	—	Cordio Medical	42 mi
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function	Phase 3	AstraZeneca	42 mi
CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVID-19	N/A	University of California, San Francisco	42 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study	Phase 2/3	Kardigan, Inc.	42 mi
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction	N/A	Edwards Lifesciences	42 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2	Phase 3	Mezzion Pharma Co. Ltd	42 mi
Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior	Phase 2/3	University of Utah	42 mi
Volunteers to Investigate Best Results for Ablation and Novel Therapies for Atrial Fibrillation	—	University of California, San Francisco	42 mi
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC	Phase 1	Tenaya Therapeutics	42 mi
Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System	N/A	Laplace Interventional, Inc	42 mi
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy	Phase 2	Imbria Pharmaceuticals, Inc.	42 mi
ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System	N/A	Edwards Lifesciences	42 mi
TECTONIC CAD IVL IDE Study	N/A	Abbott Medical Devices	42 mi
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure	N/A	Procyrion	42 mi
NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial	Phase 2	Kaiser Permanente	42 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure	N/A	Abbott Medical Devices	42 mi
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)	—	Tenaya Therapeutics	42 mi
The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study	N/A	Brigham and Women's Hospital	42 mi
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study	N/A	Ancora Heart, Inc.	42 mi
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy	Phase 2	Novo Nordisk A/S	42 mi
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction	Phase 1/2	Sardocor Corp.	42 mi
ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients	N/A	Vivek Reddy	42 mi
Evaluation of Efficacy and Safety of THRV-1268 in Long QT Syndrome Type 2 (LQTS 2)	Phase 2/3	Thryv Therapeutics, Inc.	42 mi
FORWARD CAD IDE Study	N/A	Shockwave Medical, Inc.	42 mi
Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block	—	The Hospital for Sick Children	42 mi
TTVR Early Feasibility Study	N/A	Medtronic Cardiovascular	42 mi
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia	Phase 3	Novartis Pharmaceuticals	42 mi
A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment	—	Ipsen	42 mi
Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome	Phase 3	Albireo, an Ipsen Company	42 mi
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions	N/A	Teleflex	45 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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