Heart Disease Clinical Trials in Tennessee

113 recruiting studies across 2 cities

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All Trials in Tennessee

Phase

Trial	Phase	Sponsor	Dist.
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity	Phase 3	SWOG Cancer Research Network	<1 mi
Product Surveillance Registry	—	Medtronic	<1 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement	N/A	University of British Columbia	<1 mi
STOP AF First Post-Approval Study	—	Medtronic Cardiac Ablation Solutions	<1 mi
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)	Phase 3	Anthos Therapeutics, Inc.	<1 mi
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)	Phase 3	Eli Lilly and Company	<1 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS	Phase 3	DalCor Pharmaceuticals	<1 mi
The NODE-202 Study (Study of Etripamil Nasal Spray in Pediatric Patients)	Phase 2	Milestone Pharmaceuticals Inc.	<1 mi
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women	Phase 3	Weill Medical College of Cornell University	<1 mi
PARTNER 3 Trial - Aortic Valve-in-Valve	N/A	Edwards Lifesciences	<1 mi
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes	Phase 4	VA Office of Research and Development	<1 mi
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis	Phase 2/3	CSL Behring	<1 mi
PREEMIE: Study for Treatment of PDA in Premature Infants	N/A	Merit Medical Systems, Inc.	<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery	Phase 3	Yale University	<1 mi
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities	Phase 3	Weill Medical College of Cornell University	<1 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)	Phase 3	Boehringer Ingelheim	<1 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)	N/A	University of Michigan	<1 mi
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function	Phase 3	AstraZeneca	<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease	—	Children's Hospital Medical Center, Cincinnati	<1 mi
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants	N/A	Nationwide Children's Hospital	<1 mi
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)	Phase 2/3	Merck Sharp & Dohme LLC	<1 mi
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction	N/A	Edwards Lifesciences	<1 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure	N/A	Abbott Medical Devices	<1 mi
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients	Phase 3	Colorado Prevention Center	<1 mi
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure	N/A	BrioHealth Solutions, Inc.	<1 mi
Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET	Phase 2	St. Jude Children's Research Hospital	<1 mi
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence	N/A	University of Tennessee	<1 mi
Familial Investigations of Childhood Cancer Predisposition	—	St. Jude Children's Research Hospital	<1 mi
A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment	—	Ipsen	<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy	Phase 3	Pierre Fabre Medicament	<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy	Phase 4	Dennis M. McNamara, MD, MS	<1 mi
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR	N/A	Edwards Lifesciences	<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products	—	Medtronic	<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction	Phase 3	Cytokinetics	<1 mi
ELUCIDATE FFRct Study	—	Elucid Bioimaging Inc.	<1 mi
Wearable Technology to Evaluate Hyperglycemia and HRV in DMD - Longitudinal Aim	—	Vanderbilt University Medical Center	<1 mi
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III	N/A	Endotronix, Inc.	<1 mi
RESPONDER-HF Trial	N/A	Corvia Medical	<1 mi
BoxX-NoAF Clinical Trial	N/A	AtriCure, Inc.	<1 mi
J-Valve Transfemoral Pivotal Study	N/A	JC Medical, Inc., an affiliate of Edwards Lifesciences LLC	<1 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events	Phase 3	Amgen	<1 mi
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk	Phase 3	Population Health Research Institute	<1 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)	—	Bristol-Myers Squibb	<1 mi
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm	N/A	Kardion Inc	<1 mi
Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair	N/A	NeoChord	<1 mi
AMEND TS Early Feasibility Study	N/A	Valcare Medical Ltd.	<1 mi
Addressing Under-treatment and Health Equity in AS and MR Using an Integrated EHR Platform	N/A	Tempus AI	<1 mi
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)	Phase 3	NYU Langone Health	<1 mi
Respiratory Strength Training in Heart Transplant Recipients	N/A	Vanderbilt University Medical Center	<1 mi
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study	N/A	W.L.Gore & Associates	<1 mi
The ENCIRCLE Trial	N/A	Edwards Lifesciences	<1 mi
SELUTION 4 De Novo Small Vessel IDE Trial	N/A	M.A. Med Alliance S.A.	<1 mi
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients	Phase 4	University of Rochester	<1 mi
Cooperative Assessment of Late Effects for SCD Curative Therapies	—	Vanderbilt University Medical Center	<1 mi
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry	—	SCAD Alliance	<1 mi
Vanderbilt Memory and Aging Project	—	Vanderbilt University Medical Center	<1 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial	N/A	Edwards Lifesciences	<1 mi
Augmented Pacing for Shock in the Cardiac Intensive Care Unit	N/A	Vanderbilt University Medical Center	<1 mi
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II	N/A	Shockwave Medical, Inc.	<1 mi
REHAB Fontan Failure: A Trial of Cardiac Rehabilitation	N/A	Stanford University	<1 mi
Prevail Global Study	N/A	Medtronic Vascular	<1 mi
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves	N/A	Edwards Lifesciences	<1 mi
ELEVATE-HFpEF Clinical Study	N/A	Medtronic Cardiac Rhythm and Heart Failure	<1 mi
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2	Phase 3	Tenax Therapeutics, Inc.	<1 mi
Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions	N/A	Vanderbilt University Medical Center	<1 mi
Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)	N/A	VDyne, Inc.	<1 mi
Abbott Cephea Mitral Valve Disease Registry	—	Abbott Medical Devices	<1 mi
Randomized Trial of SGLT2i in Heart Transplant Recipients	Phase 4	VA Office of Research and Development	<1 mi
Exercise Testing After Preeclampsia	—	Vanderbilt University Medical Center	<1 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.	N/A	Medtronic Cardiovascular	<1 mi
Cephea Early Feasibility Study	N/A	Abbott Medical Devices	<1 mi
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM	—	Cordio Medical	<1 mi
Wearable Technology to Evaluate Hyperglycemia and HRV in DMD	—	Vanderbilt University Medical Center	<1 mi
Cord Clamping Among Neonates With Congenital Heart Disease	N/A	Carl Backes, MD	<1 mi
EFS of the CardioMech MVRS	N/A	CardioMech AS	<1 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study	Phase 2/3	Kardigan, Inc.	<1 mi
Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)	N/A	Varian, a Siemens Healthineers Company	<1 mi
SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery	Phase 4	Vanderbilt University Medical Center	<1 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2	Phase 3	Mezzion Pharma Co. Ltd	<1 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin	Phase 3	AstraZeneca	<1 mi
Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System	N/A	Laplace Interventional, Inc	<1 mi
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
The Vanderbilt Atrial Fibrillation Ablation Registry	—	Vanderbilt University	<1 mi
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)	N/A	XVIVO Perfusion	<1 mi
Defining the Risk of Ventricular Tachycardia in Genetic Cardiomyopathies	—	Vanderbilt University Medical Center	<1 mi
Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs	—	Inova Health Care Services	<1 mi
Defining the Risk of Ventricular Tachycardia in Genetic Forms of Early-onset Atrial Fibrillation	—	Vanderbilt University Medical Center	<1 mi
TVMR With the INNOVALVE System Trial - Early Feasibility Study	N/A	Edwards Lifesciences	<1 mi
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures	—	Boston Children's Hospital	<1 mi
OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels	—	Inova Health Care Services	<1 mi
Trisol System EFS Study	N/A	Trisol Medical	<1 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE	—	Medtronic Cardiovascular	<1 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR	N/A	Cardiac Dimensions, Inc.	<1 mi
Prospective Phenotyping for Genetic Subtypes of Early-onset Atrial Fibrillation	—	Vanderbilt University Medical Center	<1 mi
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study	N/A	Ancora Heart, Inc.	<1 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events	N/A	Cleerly, Inc.	<1 mi
Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT	N/A	Thermedical, Inc.	<1 mi
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy	Phase 2	Novo Nordisk A/S	<1 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions	N/A	Concept Medical Inc.	<1 mi
A Basket Study of Vosoritide in Children With Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment	Phase 2	BioMarin Pharmaceutical	<1 mi
ATrial Tachycardia PAcing Therapy in Congenital Heart	—	Ian Law	<1 mi
Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)	N/A	Innoventric LTD	<1 mi
The CONFORM Pivotal Trial	N/A	Conformal Medical, Inc	<1 mi
Home-Based Cardiac Rehabilitation for Patients With Heart Failure	N/A	Vanderbilt University Medical Center	<1 mi
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention	Phase 4	Duke University	<1 mi
FORWARD CAD IDE Study	N/A	Shockwave Medical, Inc.	<1 mi
Tracking Results of Ablations to Combat AF Registry Generation 2	—	AtriCure, Inc.	<1 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)	—	Duke University	<1 mi
Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome	Phase 3	Albireo, an Ipsen Company	<1 mi
The Fourth Left Atrial Appendage Occlusion Study	N/A	Hamilton Health Sciences Corporation	9 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy	Phase 3	Lexicon Pharmaceuticals	14 mi
Assessment of CCM in HF With Higher Ejection Fraction	N/A	Impulse Dynamics	14 mi
Pivotal Study for the Cardiac Performance System (CPS)	—	Sensydia Corporation	14 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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