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Dexamethasone Vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

NOT_RECRUITINGPhase 4Sponsored by Poznan University of Medical Sciences
No longer actively recruiting
PhasePhase 4
SponsorPoznan University of Medical Sciences
Started2024-08-13
Est. completion2025-07-30
Eligibility
Age18 Years – 100 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06470100

Summary

Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for knee arthroplasty

Eligibility

Age: 18 Years – 100 YearsHealthy volunteers accepted
Inclusion Criteria:

* patients undergoing primary hip arthroplasty
* aged \>18 years and \<100 years
* ASA physical status 1, 2 or 3.

Exclusion Criteria:

* if they refused to participate,
* had a history of opioid abuse,
* had an infection of the site of needle puncture,
* were less than 18 years of age,
* were postponed as having ASA 4 or 5,
* had an allergy to any of the drugs used in the study,
* renal failure (estimated glomerular filtration rate \<15ml/min/1.73m2),
* liver failure,
* known or suspected coagulopathy,
* pre-existing anatomical or neurological disorders in the lower extremities,
* intellectual disability with problems in pain evaluation,
* severe psychiatric illness.

Conditions5

ArthritisKnee ArthritisKnee DiseaseKnee OsteoarthritisKnee Pain Chronic

Interventions3

0.9% Sodium Chloride InjectionDexamethasoneDexmedetomidine

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