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Heart Disease Clinical Trials in Pennsylvania

156 recruiting studies across 1 city

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All Trials in Pennsylvania

Phase
Trial Phase Dist.
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACSPhase 3<1 mi
Assessment of CCM in HF With Higher Ejection FractionN/A<1 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled StudyPhase 2/3<1 mi
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and InflammationPhase 3<1 mi
RESPONDER-HF TrialN/A<1 mi
A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old.Phase 4<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and RecoveryPhase 3<1 mi
Optimal Ventilation for Cardiac ArrestN/A<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease<1 mi
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy<1 mi
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma<1 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2Phase 3<1 mi
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic DysfunctionPhase 3<1 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative<1 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular EventsPhase 3<1 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)Phase 3<1 mi
Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation<1 mi
Left vs Left Randomized Clinical TrialN/A<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products<1 mi
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)Phase 3<1 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical TrialN/A<1 mi
Transfusion Requirements in Younger Patients Undergoing Cardiac SurgeryN/A<1 mi
Fontan Fitness TrialN/A<1 mi
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart FailurePhase 4<1 mi
VIZ ACCESS HCM - Multi-Site Registry<1 mi
Characterization of Cardiac Electrophysiological Effects of Autonomic NeuromodulationEarly 1<1 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR VariantPhase 3<1 mi
Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst<1 mi
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)<1 mi
The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.<1 mi
Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children<1 mi
PARTNER 3 Trial - Aortic Valve-in-ValveN/A<1 mi
Autus Valve Pivotal StudyN/A<1 mi
An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement SystemN/A<1 mi
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve StenosisPhase 2<1 mi
Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL AmyloidosisPhase 3<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum CardiomyopathyPhase 4<1 mi
Prospective 4D CTA of BAV Competence<1 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious InfectionsPhase 3<1 mi
Abatacept in Immune Checkpoint Inhibitor MyocarditisPhase 3<1 mi
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) PatientsPhase 4<1 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABGPhase 3<1 mi
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry<1 mi
Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants<1 mi
Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)<1 mi
Penn Medicine Healthy HeartN/A<1 mi
A Study of SGT-212 Gene Therapy in Friedreich's AtaxiaPhase 1<1 mi
MASA Valve Early Feasibility StudyN/A<1 mi
TEE 3D RV Assessment for SAVR, Mini AVR, and TAVR<1 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic CardiomyopathyPhase 3<1 mi
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)Phase 1<1 mi
AI Powered Mapping Technology for Identifying Arrhythmias<1 mi
Valved Graft PMCF Study<1 mi
A Gene Therapy Study of RP-A501 in Male Patients With Danon DiseasePhase 2<1 mi
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCMPhase 1/2<1 mi
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With CardiomyopathyPhase 3<1 mi
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction<1 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in WomenN/A<1 mi
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and InflammationPhase 3<1 mi
EluPro Antibiotic-Eluting BioEnvelope Registry<1 mi
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)Phase 2<1 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial FibrillationPhase 3<1 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment<1 mi
Clinical Study of the inQB8 TTVR SystemN/A<1 mi
Calculating Wall Shear Stress in Infant Pulmonary VeinsPhase 1<1 mi
Randomized Assessment of TcMS for VT StormN/A<1 mi
Beta-blocker Administration for Cardiomyocyte DivisionPhase 1<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)N/A<1 mi
The Fourth Left Atrial Appendage Occlusion StudyN/A<1 mi
Intra-aortic Balloon Counterpulsation (IABC) Compliance<1 mi
Cord Clamping Among Neonates With Congenital Heart DiseaseN/A<1 mi
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets<1 mi
Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart FailurePhase 4<1 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)N/A<1 mi
The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)N/A<1 mi
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney FunctionPhase 3<1 mi
Low Dose Vasopressin vs Phenylephrine in Cardiac SurgeryPhase 4<1 mi
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF StudyN/A<1 mi
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)N/A<1 mi
Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)N/A<1 mi
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight InfantsN/A<1 mi
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)Phase 2/3<1 mi
Resuscitative TEE Collaborative Registry<1 mi
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™N/A<1 mi
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionN/A<1 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With DapagliflozinPhase 3<1 mi
CTSN Embolic Protection TrialN/A<1 mi
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device ImplantationN/A<1 mi
Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression<1 mi
A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE)Phase 2<1 mi
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting<1 mi
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)N/A<1 mi
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart FailureN/A<1 mi
Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant RecipientsPhase 2<1 mi
Fibrosis and the FontanPhase 1/2<1 mi
ASCEND CSP IDE StudyN/A<1 mi
His-Bundle Corrective Pacing in Heart FailureN/A<1 mi
TVMR With the INNOVALVE System Trial - Early Feasibility StudyN/A<1 mi
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures<1 mi
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry<1 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMRN/A<1 mi
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF StudyN/A<1 mi
Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VTN/A<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection FractionPhase 3<1 mi
Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive ProcedureN/A<1 mi
Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)N/A<1 mi
Pivotal Study for the Cardiac Performance System (CPS)<1 mi
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)Phase 1<1 mi
Foundational Programs to Combat Clinician StressN/A<1 mi
PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID TrialN/A<1 mi
Cholate Clearance in Fontan and Heart Failure<1 mi
Long-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US)<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and ChemotherapyPhase 3<1 mi
Product Surveillance Registry3 mi
Prevail Global StudyN/A3 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve ReplacementN/A3 mi
Lymphatic System Stimulation in Heart FailureN/A3 mi
The HEARTFELT StudyN/A5 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac ToxicityPhase 37 mi
The CONFORM Pivotal TrialN/A7 mi
Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)Phase 27 mi
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVRN/A7 mi
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2Phase 37 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.N/A7 mi
Medtronic Terminate AF StudyN/A7 mi
ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt SystemN/A7 mi
Trisol System EFS StudyN/A7 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE7 mi
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular InterventionPhase 47 mi
Ultrafiltration Versus IV Diuretics in Worsening Heart FailureN/A12 mi
Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)Phase 212 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart FailureN/A12 mi
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular HypertrophyPhase 212 mi
Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure14 mi
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation SystemN/A14 mi
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and ObesityPhase 314 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular EventsN/A14 mi
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)Phase 316 mi
BIOTRONIK Conduction System Pacing With the Solia Lead - Solia CSP SN/A18 mi
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing DialysisPhase 2/325 mi
A Basket Study of Vosoritide in Children With Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone TreatmentPhase 225 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)25 mi
Tezspire Cardiac Events PASS25 mi
SPHERE Per-AF Post-Approval Study25 mi
PULSED AF Post-Approval Study25 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the HeartPhase 326 mi
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEmN/A31 mi
Left Ventricular Structural Predictors of Sudden Cardiac Death36 mi
A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CADN/A42 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small VesselsN/A45 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery LesionsN/A45 mi
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart FailurePhase 346 mi
Heart Attack Research Program- Imaging Study48 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)48 mi
Women's Heart Attack Research Program: Stress Ancillary StudyN/A48 mi
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval StudyN/A48 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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