| Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)NCT07100990 · Scottsdale, Arizona | Phase 3 | 33 |
| Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical CancerNCT05051722 · Phoenix, Arizona | — | 24 |
| Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase InhibitorsNCT06028022 · Albert Lea, Minnesota | Phase 2 | 23 |
| Wisconsin Ginseng for Decreasing Cancer Related FatigueNCT06395441 · Albert Lea, Minnesota | Phase 3 | 15 |
| Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal AdenocarcinomaNCT03961945 · Scottsdale, Arizona | Not applicable | 9 |
| Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome PatientsNCT05410977 · Scottsdale, Arizona | — | 9 |
| Pancreatic Cancer Detection Consortium (PCDC) Prospective CohortsNCT06271291 · Scottsdale, Arizona | — | 9 |
| SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE TrialNCT05222620 · Scottsdale, Arizona | Phase 2 | 7 |
| Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment PlanningNCT06200116 · Scottsdale, Arizona | — | 7 |
| Understanding the Mechanisms of Clonal and Non-clonal Cytopenia Following CAR-T Therapy for Multiple Myeloma or CD19+ Lymphoproliferative Disorder (LPD)NCT06630104 · Scottsdale, Arizona | Not applicable | 7 |
| Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell TherapyNCT06834373 · Scottsdale, Arizona | Phase 2 | 7 |
| SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate AdenocarcinomaNCT06205316 · Scottsdale, Arizona | Phase 3 | 6 |
| Evaluating the Association Among Changes in Gut Microbiome, Fatigue, and Chemotherapy-Induced Nausea in Early Stage Breast CancerNCT05417867 · Scottsdale, Arizona | — | 5 |
| Low Dose Aspirin for the Prevention of Postpartum Related Breast CancerNCT05557877 · Scottsdale, Arizona | Phase 2 | 5 |
| Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal SamplesNCT06071845 · Scottsdale, Arizona | Not applicable | 5 |
| Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate CancerNCT06325046 · Albert Lea, Minnesota | Not applicable | 5 |
| Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic LeukemiaNCT03418038 · Mankato, Minnesota | Phase 2 | 4 |
| Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain TumorsNCT03750227 · Scottsdale, Arizona | Phase 3 | 4 |
| Biomarkers to Predict Cancer Therapy-related CardiotoxicityNCT06353191 · Scottsdale, Arizona | — | 4 |
| Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic DisordersNCT00830557 · Phoenix, Arizona | — | 3 |
| Pre-myeloid Cancer and Bone Marrow Failure Clinic StudyNCT02958462 · Scottsdale, Arizona | Not applicable | 3 |
| Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaNCT03516617 · Scottsdale, Arizona | Phase 2 | 3 |
| Understanding of Genetics by Men at Risk for Prostate CancerNCT04550845 · Phoenix, Arizona | Not applicable | 3 |
| Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the BoneNCT05033288 · Scottsdale, Arizona | — | 3 |
| Role of Gut Microbiome in Cancer TherapyNCT05112614 · Scottsdale, Arizona | — | 3 |
| Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaNCT05388006 · Palo Alto, California | Phase 2 | 3 |
| De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNANCT05541016 · Scottsdale, Arizona | Phase 2 | 3 |
| Vaccine Therapy Plus Pembrolizumab in Treating Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cavity CancerNCT05920798 · Scottsdale, Arizona | Phase 1/2 | 3 |
| INTERogating Cancer for Etiology, Prevention and Therapy NavigationNCT06008392 · Scottsdale, Arizona | — | 3 |
| Enfortumab Vedotin for the Treatment of Patients With Metastatic or Unresectable Squamous Cell Carcinoma of the PenisNCT06104618 · Phoenix, Arizona | Phase 2 | 3 |
| A Collaborative Intervention for Improving Cancer Pain Management in Cancer SurvivorsNCT06198010 · Scottsdale, Arizona | Not applicable | 3 |
| Identification and Differentiation of Thyroid Nodules by Acoustic Imaging and Viscoelastic ParametersNCT06207188 · Scottsdale, Arizona | — | 3 |
| Immune Profile of Acute Myeloid Leukemia Patients Receiving Azacitidine Plus Venetoclax Induction ChemotherapyNCT06279572 · Scottsdale, Arizona | — | 3 |
| Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic PlatformNCT06349642 · Phoenix, Arizona | — | 3 |
| Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia With an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients With Post-Menopausal BleedingNCT06365905 · Scottsdale, Arizona | — | 3 |
| Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE TrialNCT06378866 · Phoenix, Arizona | Phase 2 | 3 |
| Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT TrialNCT06639074 · Scottsdale, Arizona | Phase 2 | 3 |
| Outcomes of Low-Risk Endometrial Cancer With Isolated Tumor Cells in the Sentinel Lymph Nodes: A Prospective, Multicenter, Single-Arm Observational StudyNCT06689956 · Rochester, Minnesota | — | 3 |
| Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis/Acute Pancreatitis Associated Diabetes MellitusNCT06729996 · Rochester, Minnesota | Phase 2 | 3 |
| Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal HypertensionNCT06797193 · Scottsdale, Arizona | Not applicable | 3 |
| Multi-Cancer Detection Observational Cohort StudyNCT06962995 · Scottsdale, Arizona | — | 3 |
| Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With GlioblastomaNCT07091864 · Phoenix, Arizona | Not applicable | 3 |
| BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic AdenocarcinomaNCT07226856 · Scottsdale, Arizona | Phase 2 | 3 |
| A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or LymphomaNCT03017820 · Scottsdale, Arizona | Phase 1 | 2 |
| Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's DiseaseNCT03821857 · Jacksonville, Florida | Phase 4 | 2 |
| A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In SituNCT04144023 · Jacksonville, Florida | Phase 1 | 2 |
| Cancer Genetic Testing in Ethnic PopulationsNCT04475640 · Scottsdale, Arizona | Not applicable | 2 |
| Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma TrialNCT05030298 · Phoenix, Arizona | Phase 1 | 2 |
| Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer PatientsNCT05045066 · Scottsdale, Arizona | Early phase 1 | 2 |
| Influence of Pulse Electromagnetic Field Therapy on Myocardial IschemiaNCT05111288 · Scottsdale, Arizona | Not applicable | 2 |
| TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast CancerNCT05507879 · Gainesville, Florida | — | 2 |
| The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia PatientsNCT05876923 · Scottsdale, Arizona | Not applicable | 2 |
| Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA TrialNCT05898646 · Scottsdale, Arizona | Phase 2 | 2 |
| At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced CancerNCT05969860 · Jacksonville, Florida | Phase 2 | 2 |
| Effect of Vagal Nerve Stimulation on Gastric Motor FunctionsNCT06038929 · Minneapolis, Minnesota | Not applicable | 2 |
| Primary Breast Oligoprogressive Sites Treated With Radiotherapy to Obviate the Need to Change Systemic TherapyNCT06055881 · Scottsdale, Arizona | Not applicable | 2 |
| Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRINCT06315595 · Scottsdale, Arizona | — | 2 |
| Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic EncephalopathyNCT06425380 · Rochester, Minnesota | Not applicable | 2 |
| Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell LymphomaNCT06508463 · Scottsdale, Arizona | Phase 1 | 2 |
| Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate CancerNCT06625034 · Scottsdale, Arizona | Phase 3 | 2 |
| Rilonacept in Subjects With Cardiac SarcoidosisNCT06660732 · Baltimore, Maryland | Phase 2 | 2 |
| Q702 for the Treatment of Patients With Hematologic MalignanciesNCT06712810 · Scottsdale, Arizona | Phase 1 | 2 |
| Pulmonary Rehabilitation for Rural Patients With COPDNCT06847061 · Scottsdale, Arizona | Not applicable | 2 |
| A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With GliomaNCT07074756 · Jacksonville, Florida | Not applicable | 2 |
| Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS TrialNCT07089927 · Scottsdale, Arizona | Not applicable | 2 |
| Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR TrialNCT07188532 · Phoenix, Arizona | Not applicable | 2 |
| Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer RiskNCT07207564 · Jacksonville, Florida | — | 2 |
| Enhancing Brain And Mental Health Through Breathing PracticeNCT07369752 · Albert Lea, Minnesota | Not applicable | 2 |
| Family Study of Lymphoproliferative DisordersNCT00626496 · Rochester, Minnesota | — | 1 |
| The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) RegistryNCT01429727 · Rochester, Minnesota | — | 1 |
| Mayo Clinic Radiotherapy Patient Outcomes Registry and Biobanking StudyNCT02457962 · Rochester, Minnesota | — | 1 |
| Mayo Clinic Upper Digestive Disease SurveyNCT02530983 · Rochester, Minnesota | — | 1 |
| Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal StudyNCT02740634 · Rochester, Minnesota | Not applicable | 1 |
| Genetic Markers of Cardiovascular Disease in EpilepsyNCT02824822 · Rochester, Minnesota | — | 1 |
| Testicular Tissue Cryopreservation in ChildrenNCT02872532 · Rochester, Minnesota | Not applicable | 1 |
| Mayo AVC Registry and BiobankNCT03049254 · Rochester, Minnesota | — | 1 |
| The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and ScarringNCT03155854 · Rochester, Minnesota | Not applicable | 1 |
| Biobank for Cholestatic Liver Diseases.NCT03445585 · Rochester, Minnesota | — | 1 |
| Gynecologic Extramammary Paget's DiseaseNCT03564483 · Rochester, Minnesota | — | 1 |
| Intravital Microscopy in Human Solid TumorsNCT03823144 · Jacksonville, Florida | Not applicable | 1 |
| Molecular Detection of Advanced Neoplasia in Pancreatic CystsNCT03855800 · Rochester, Minnesota | Not applicable | 1 |
| Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and DyspepsiaNCT03865290 · Rochester, Minnesota | Phase 2 | 1 |
| Long-term, Substantial Weight Loss and Insulin Regulation of LipolysisNCT03868592 · Rochester, Minnesota | Not applicable | 1 |
| Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver CancerNCT03942328 · Rochester, Minnesota | Phase 1/2 | 1 |
| Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System MalignanciesNCT04047264 · Rochester, Minnesota | Not applicable | 1 |
| Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation TherapyNCT04082520 · Rochester, Minnesota | Phase 2 | 1 |
| MR Evaluation of Cerebrospinal Fluid (CSF) DynamicsNCT04099823 · Rochester, Minnesota | Not applicable | 1 |
| A Prospective Observational Study of Foam Sclerotherapy .NCT04111692 · Rochester, Minnesota | — | 1 |
| Globus Pallidus Stimulation to Treat InsomniaNCT04116996 · Jacksonville, Florida | Not applicable | 1 |
| Thoracic Specimen RegistryNCT04118660 · Rochester, Minnesota | — | 1 |
| Obstructive Sleep Apnea Among Somali-AmericansNCT04124848 · Rochester, Minnesota | — | 1 |
| Investigating the Link Between Type 2 Immunity and NAFLD in Human ObesityNCT04232566 · Scottsdale, Arizona | — | 1 |
| The Olmsted NAFLD Epidemiology Study (TONES)NCT04365855 · Rochester, Minnesota | Not applicable | 1 |
| Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast CancerNCT04517838 · Jacksonville, Florida | — | 1 |
| Examination of the Impact of CalmiGo's Stress Management Device on Vascular Heath and Cardiovascular Disease Risk.NCT04521699 · Rochester, Minnesota | Not applicable | 1 |
| A Vaccine (MV-s-NAP) for the Treatment of Patients With Invasive Metastatic Breast CancerNCT04521764 · Rochester, Minnesota | Phase 1 | 1 |
| Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PACNCT04605913 · Jacksonville, Florida | Phase 1/2 | 1 |
| Cerebrospinal Fluid Biomarkers for Brain TumorsNCT04692324 · Rochester, Minnesota | — | 1 |
| Ommaya Reservoir Placement for Brain Tumor Biomarker AccessNCT04692337 · Rochester, Minnesota | Not applicable | 1 |
| 3D Ultrasound Breast ImagingNCT04692818 · Rochester, Minnesota | Not applicable | 1 |
| Development of Patient Derived Xenografts (PDX) in Patients With Breast CancerNCT04703244 · Rochester, Minnesota | — | 1 |
| Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC PatientsNCT04753996 · Rochester, Minnesota | — | 1 |
| Prospective Sinonasal Cancer Multi-institution StudyNCT04755855 · Rochester, Minnesota | — | 1 |
| MRI-Guided Cryoablation for Focal Native Prostate CancerNCT04797039 · Rochester, Minnesota | — | 1 |
| Quantitative Microvasculature Imaging for Breast Cancer Detection and MonitoringNCT04799535 · Rochester, Minnesota | — | 1 |
| Breast Cancer, Reasoning, and Activity InterventionNCT04816006 · Phoenix, Arizona | Not applicable | 1 |
| Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal MetastasisNCT04858009 · Rochester, Minnesota | Phase 2 | 1 |
| CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell MalignanciesNCT04892277 · Rochester, Minnesota | Phase 1 | 1 |
| A Study to Evaluate Breathing Muscle Training in Cardiac RehabNCT04984473 · Rochester, Minnesota | Not applicable | 1 |
| Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic CoughNCT05110144 · Rochester, Minnesota | Phase 2 | 1 |
| Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart DiseasesNCT05122962 · Rochester, Minnesota | — | 1 |
| Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid TumorsNCT05269381 · Jacksonville, Florida | Phase 1/2 | 1 |
| Dietary and Topical Magnesium Replacement or Supplementation in Patients With LymphomaNCT05294367 · Rochester, Minnesota | Early phase 1 | 1 |
| Patient Derived Preclinical ModelsNCT05324553 · Rochester, Minnesota | — | 1 |
| Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral NeuropathyNCT05411523 · Rochester, Minnesota | — | 1 |
| MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate CancerNCT05438563 · Rochester, Minnesota | Not applicable | 1 |
| Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix CommunitiesNCT05447923 · Scottsdale, Arizona | Not applicable | 1 |
| Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent GlioblastomaNCT05465954 · Rochester, Minnesota | Phase 2 | 1 |
| Adverse Outcomes and Mortality in Liver TransplantNCT05477277 · Phoenix, Arizona | Not applicable | 1 |
| Investigational Scan (68Ga-FAPI-46 PET/CT) for Imaging of Cancer-Associated Fibroblasts for Localized Pancreatic Ductal AdenocarcinomaNCT05518903 · Rochester, Minnesota | Phase 2 | 1 |
| Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue SarcomaNCT05526417 · Scottsdale, Arizona | Not applicable | 1 |
| Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor RemovalNCT05530759 · Rochester, Minnesota | — | 1 |
| Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap NeoplasmsNCT05549661 · Rochester, Minnesota | Phase 1 | 1 |
| Evaluation of 18F-TFB PET/CT Scan in Patients With Differentiated Thyroid CancerNCT05575440 · Rochester, Minnesota | — | 1 |
| Group Curriculum for Improving Survivorship Outcomes in Adolescent and Young Adult Cancer SurvivorsNCT05584449 · Scottsdale, Arizona | Not applicable | 1 |
| 3D Ultrasound for the Imaging of Lymph Nodes in Patients With Breast CancerNCT05704283 · Rochester, Minnesota | Early phase 1 | 1 |
| Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade GliomaNCT05717153 · Rochester, Minnesota | Early phase 1 | 1 |
| Extracellular Impact of Ultrasound-induced Blood-brain Barrier DisruptionNCT05733312 · Rochester, Minnesota | Not applicable | 1 |
| Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung CancerNCT05746325 · Jacksonville, Florida | Not applicable | 1 |
| Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Treatment of Gastric Cancer With Limited Peritoneal Metastasis, ROBO-CHIP StudyNCT05753306 · Rochester, Minnesota | Phase 2 | 1 |
| Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing CraniotomyNCT05789394 · Jacksonville, Florida | Phase 1 | 1 |
| A Study of Ketamine Infusions to Treat Clinically-depressed ICU PatientsNCT05803551 · Jacksonville, Florida | Phase 2 | 1 |
| Alternate Doses and Dosing Schedules of Belantamab Mafodotin for Treatment of Triple-Class Refractory Multiple MyelomaNCT05847569 · Jacksonville, Florida | Phase 2 | 1 |
| A Study of Invasive Hemodynamic for MACHD RegistryNCT05849025 · Rochester, Minnesota | — | 1 |
| Continuous Glucose Monitor for Mayo Clinic Advanced Care at Home PatientsNCT05880810 · Jacksonville, Florida | Not applicable | 1 |
| ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Treatment of Recurrent High-Grade GliomaNCT05917145 · Rochester, Minnesota | Phase 1 | 1 |
| A Study of Glycemic Control in Left Ventricular AssistNCT05933161 · Rochester, Minnesota | — | 1 |
| Pulmonary Hypertension in Left Heart DiseaseNCT05935605 · Rochester, Minnesota | — | 1 |
| Disparities Among Liver Transplant PatientsNCT05981196 · Phoenix, Arizona | — | 1 |
| NSAID Injection Versus Corticosteroid Injection for Basilar Thumb ArthritisNCT05992883 · Rochester, Minnesota | Phase 3 | 1 |
| Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer PatientsNCT06015932 · Rochester, Minnesota | Not applicable | 1 |
| MC210808 Venetoclax in Combination With Lenalidomide and Dexamethasone (Ven-Rd), Daratumumab and Dexamethasone (Ven-Dd), or Daratumumab-Lenalidomide-Dexamethasone (Ven-DRd) for the Treatment of Multiple MyelomaNCT06042725 · Rochester, Minnesota | Phase 1 | 1 |
| Social Determinants of Health in Hepatobiliary Cancer PatientsNCT06053333 · Rochester, Minnesota | — | 1 |
| A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's DiseaseNCT06057909 · Scottsdale, Arizona | — | 1 |
| Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast AbnormalitiesNCT06058650 · Rochester, Minnesota | Not applicable | 1 |
| Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic CholangiocarcinomaNCT06058663 · Jacksonville, Florida | Phase 1 | 1 |
| Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer TypesNCT06075524 · Rochester, Minnesota | — | 1 |
| Bladder Bank (a Prospective Banking Study)NCT06109857 · Rochester, Minnesota | — | 1 |
| Study of Human Brain-Gut Axis and Gut Microbiome in Patients With Brain Lesions - Repository for Neuroscience ResearchNCT06117930 · Jacksonville, Florida | — | 1 |
| A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung CancerNCT06122064 · Rochester, Minnesota | Not applicable | 1 |
| Remote Monitoring With Health-Coaching to Improve Quality of Life in Older Patients With Multiple MyelomaNCT06145581 · Rochester, Minnesota | Not applicable | 1 |
| A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)NCT06150560 · Rochester, Minnesota | Phase 3 | 1 |
| A Prospective Registry for Patients at High-Risk for Pancreatic CancerNCT06151223 · Rochester, Minnesota | — | 1 |
| Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT StudyNCT06151730 · Rochester, Minnesota | — | 1 |
| Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and ReconstructionNCT06153836 · Jacksonville, Florida | Phase 2 | 1 |
| B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic MalignanciesNCT06191887 · Jacksonville, Florida | Phase 1 | 1 |
| A Novel Molecular Approach to Blood DNA Screening for Cancer: Specificity Assessment (The NOMAD Study)NCT06192875 · Rochester, Minnesota | — | 1 |
| Contrast Echocardiography During Exercise to Assess Pulmonary Blood VolumeNCT06195059 · Rochester, Minnesota | — | 1 |
| Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate CancerNCT06200103 · Rochester, Minnesota | Phase 2 | 1 |
| Collection of Specimens and Clinical Data for Patients With Recurrent or Metastatic Breast Cancer or Male Breast CancerNCT06217874 · Rochester, Minnesota | — | 1 |
| Acceptance and Commitment Therapy and Compassion-Based Virtual Group Therapy to Improve Psychological Wellbeing in Patients With CancerNCT06246955 · Scottsdale, Arizona | Not applicable | 1 |
| Virtual Reality for Non-cardiac Chest PainNCT06262126 · Jacksonville, Florida | Not applicable | 1 |
| Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) ProgramNCT06265285 · Jacksonville, Florida | Phase 2 | 1 |
| MUSE-S Headband System for Improving Anxiety and Insomnia Among Breast Cancer SurvivorsNCT06274034 · Rochester, Minnesota | Early phase 1 | 1 |
| Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD StudyNCT06304168 · Rochester, Minnesota | — | 1 |
| Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain TumorsNCT06322602 · Rochester, Minnesota | Not applicable | 1 |
| Ravulizumab in Pregnancies Complicated by Severe Hypertensive DisordersNCT06333652 · Rochester, Minnesota | Phase 2 | 1 |
| Oropharynx (OPX) Biomarker TrialNCT06356272 · Rochester, Minnesota | — | 1 |
| Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment of Prostate CancerNCT06369610 · Scottsdale, Arizona | Phase 2 | 1 |
| Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation TherapyNCT06377696 · Rochester, Minnesota | Phase 2 | 1 |
| 3D DL Ozteo in the Detection of Osseous Changes in Patients With Inflammatory ArthritisNCT06383585 · Rochester, Minnesota | Not applicable | 1 |
| DiviTum®TKa: A Biomarker Assay for Efficacy in HR+ Breast Cancer PatientsNCT06388122 · Jacksonville, Florida | — | 1 |
| Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate CancerNCT06389786 · Jacksonville, Florida | Not applicable | 1 |
| Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor TherapyNCT06401889 · Jacksonville, Florida | — | 1 |
| Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With SarcomaNCT06409013 · Rochester, Minnesota | — | 1 |
| Insulin and Insulin Pulses During FastingNCT06424015 · Rochester, Minnesota | Not applicable | 1 |
| Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 DiabetesNCT06424106 · Rochester, Minnesota | Not applicable | 1 |
| Fasting Mimicking Diet for Reducing Immune Related Adverse Events for Cancer Patients on Immune Checkpoint Inhibitors, FMD-ICI TrialNCT06438588 · Jacksonville, Florida | Not applicable | 1 |
| Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing SurgeryNCT06450873 · Scottsdale, Arizona | Phase 2 | 1 |
| Mapping of Electrical Properties in the BrainNCT06470711 · Scottsdale, Arizona | — | 1 |
| Feasibility of Patient-Centered Home Care (PCHC) to Reduce Disparities in High-Risk Black Men (BM) With Prostate Cancer (CaP)NCT06470750 · Jacksonville, Florida | — | 1 |
| Insomnia in Patients With Metastatic Lung CancerNCT06472804 · Rochester, Minnesota | — | 1 |
| Molecular Analysis of Suspected or High-Risk Lung Cancer to Drive Individualized Care (Interception for Suspected Lung Cancer)NCT06482073 · Rochester, Minnesota | — | 1 |
| MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian CancerNCT06483048 · Scottsdale, Arizona | Phase 1 | 1 |
| Inspiratory Muscle Training in HFpEFNCT06510231 · Rochester, Minnesota | Not applicable | 1 |
| Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic Cancer Undergoing SurgeryNCT06525740 · Rochester, Minnesota | Phase 4 | 1 |
| Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast CancerNCT06525766 · Scottsdale, Arizona | Phase 2 | 1 |
| iCCaRE Consortium Pilot Project 1: Feasibility of a Point of Prostate Cancer Diagnosis Intervention for Newly Diagnosed Black MenNCT06535802 · Jacksonville, Florida | — | 1 |
| Hematopoiesis in MBL and CLL Versus Healthy Age-Matched Control SubjectsNCT06536452 · Rochester, Minnesota | — | 1 |
| Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black MenNCT06541210 · Jacksonville, Florida | Not applicable | 1 |
| Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes RiskNCT06557057 · Rochester, Minnesota | — | 1 |
| A Study of Hemodynamic Cardiopulmonary Exercise for CHDNCT06566196 · Rochester, Minnesota | Not applicable | 1 |
| Genetic Testing for the Prevention of Cancer in American Indian Communities (JUNIPER Trial)NCT06569316 · Scottsdale, Arizona | Not applicable | 1 |
| AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic DysfunctionNCT06580158 · Rochester, Minnesota | — | 1 |
| A Study to Determine Number of Patients Who Develop High Ammonia Levels After Receiving Recombinant Erwinia AsparaginaseNCT06600659 · Rochester, Minnesota | — | 1 |
| Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain FogNCT06614309 · Scottsdale, Arizona | Not applicable | 1 |
| Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast CancerNCT06635980 · Scottsdale, Arizona | Phase 2 | 1 |
| Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse EventsNCT06640010 · Jacksonville, Florida | — | 1 |
| Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung CancerNCT06660407 · Rochester, Minnesota | Phase 2 | 1 |
| An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain TumorsNCT06667726 · Rochester, Minnesota | Phase 2 | 1 |
| Intravenous Ketamine for Treatment-Resistant DepressionNCT06668571 · Rochester, Minnesota | Phase 2 | 1 |
| Biomarkers of Resiliency In Childhood Cancer SurgeryNCT06674811 · Rochester, Minnesota | — | 1 |
| Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity Using the Vigilant AppNCT06675643 · Rochester, Minnesota | — | 1 |
| Effect of Sacubitril-Valsartan on Cardiac Structure and FunctionNCT06693674 · Rochester, Minnesota | Phase 3 | 1 |
| In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE TrialNCT06704191 · Jacksonville, Florida | Phase 1/2 | 1 |
| Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed TherapyNCT06723041 · Rochester, Minnesota | Not applicable | 1 |
| Navicam for Detection of Barrett's EsophagusNCT06748911 · Jacksonville, Florida | Not applicable | 1 |
| Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)NCT06752577 · Jacksonville, Florida | — | 1 |
| CAMEO-FONTAN -Dapagliflozin in the Failing Fontan CirculationNCT06762964 · Rochester, Minnesota | Phase 2 | 1 |
| Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI TrialNCT06764095 · Rochester, Minnesota | Phase 4 | 1 |
| Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary HypertensionNCT06770023 · Jacksonville, Florida | Phase 1 | 1 |
| Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot StudyNCT06770062 · Rochester, Minnesota | — | 1 |
| Knee Injections for Obese Patients With Knee ArthritisNCT06782529 · Jacksonville, Florida | Phase 4 | 1 |
| Postoperative Outcomes and Patient Satisfaction With Mayo Clinic Florida Care Hotel After Mastectomy and Tissue Expander PlacementNCT06783179 · Jacksonville, Florida | — | 1 |
| Elotuzumab, Daratumumab, Iberdomide, and Dexamethasone for the Treatment of Relapsed Multiple MyelomaNCT06785415 · Rochester, Minnesota | Phase 1/2 | 1 |
| Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative DiseasesNCT06788886 · Rochester, Minnesota | Not applicable | 1 |
| A Randomized Controlled Trial (RCT) to Determine the Efficacy of a Multidisciplinary CBT Based Pain Management Program for the Treatment of Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) in Breast Cancer SurvivorsNCT06831838 · Jacksonville, Florida | Not applicable | 1 |
| Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal or Gynecological CancerNCT06855524 · Scottsdale, Arizona | Phase 2 | 1 |
| Weight Loss Through Mayo Clinic DietNCT06862375 · Rochester, Minnesota | Not applicable | 1 |
| A Study of Paramedic HF ManagementNCT06874556 · Rochester, Minnesota | — | 1 |
| Investigating Memory and Physical Activity After Cancer Treatment in Survivors of Adolescent and Young Adult CancersNCT06880861 · Scottsdale, Arizona | — | 1 |
| Radio- KO Radiotherapy for Knee Osteoarthritis Clinical TrialNCT06887829 · Rochester, Minnesota | Not applicable | 1 |
| Exploration of HRQOL and Urinary Outcomes Following Partial CystectomyNCT06891209 · Rochester, Minnesota | — | 1 |
| Breastmilk in Response to a Bout of ExerciseNCT06892483 · Rochester, Minnesota | — | 1 |
| Evaluation of Plasma Renin Concentrations in Cardiac SurgeryNCT06895213 · Rochester, Minnesota | — | 1 |
| Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) StudyNCT06897670 · Rochester, Minnesota | — | 1 |
| Pharmacologic Approaches to Preventing Primary Sclerosing Cholangitis Recurrence After Liver TransplantationNCT06905054 · Scottsdale, Arizona | Phase 2 | 1 |
| MTI-301 for the Treatment of Metastatic or Unresectable and Refractory Solid CancersNCT06911008 · Jacksonville, Florida | Phase 1 | 1 |
| An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid TumorsNCT06915727 · Rochester, Minnesota | Phase 3 | 1 |
| Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung CancerNCT06918132 · Rochester, Minnesota | Phase 2 | 1 |
| Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During ProstatectomyNCT06940271 · Jacksonville, Florida | Not applicable | 1 |
| Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple MyelomaNCT06940297 · Rochester, Minnesota | Phase 2 | 1 |
| Evaluating a Mobile Health Application Intervention for Caregiver Instruction in Manual Therapy for Chemotherapy-Induced Peripheral NeuropathyNCT06945380 · Jacksonville, Florida | Not applicable | 1 |
| Collecting Patient-Reported Experiences With Radiation Dermatitis in Breast Cancer Patients Undergoing RadiotherapyNCT06953245 · Rochester, Minnesota | — | 1 |
| Contrast-Enhanced Photon-Counting Detector CT (PCD-CT) for the Local Staging of Rectal CancerNCT06965166 · Rochester, Minnesota | — | 1 |
| The Role of Islet GLP-1 in the Pathogenesis of PrediabetesNCT06967558 · Rochester, Minnesota | Phase 2 | 1 |
| The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 DiabetesNCT06976619 · Rochester, Minnesota | Phase 2 | 1 |
| Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States PopulationNCT06997068 · Rochester, Minnesota | Phase 2 | 1 |
| Decitabine in Combination With Standard of Care Therapy for the Treatment of Surgically Resectable HPV-Negative Head and Neck CancerNCT06997094 · Jacksonville, Florida | Phase 1 | 1 |
| An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The UTMOST2 TrialNCT06999798 · Rochester, Minnesota | Phase 1 | 1 |
| A Study of Live Tumor Fragments of Surgical ResectionsNCT07000864 · Jacksonville, Florida | — | 1 |
| Inpatient Use of Personal Continuous Glucose Monitor (CGM) to Improve Diabetes Mellitus ControlNCT07006480 · Jacksonville, Florida | Not applicable | 1 |
| Deciphering Preserved Autonomic Function After Multiple SclerosisNCT07012135 · Rochester, Minnesota | Not applicable | 1 |
| Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual DiseaseNCT07025226 · Rochester, Minnesota | Early phase 1 | 1 |
| Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA TrialNCT07025369 · Scottsdale, Arizona | Phase 2 | 1 |
| 5-strain Probiotic Formulation in HR-positive Breast Cancer Receiving Aromatase Inhibitor to Prevent Bone LossNCT07044310 · Jacksonville, Florida | Phase 2 | 1 |
| A 3D-Printed External Breast Prosthesis for the Improvement of Patient-reported Outcomes Among Breast Cancer Patients That Underwent a Mastectomy Without ReconstructionNCT07047872 · Rochester, Minnesota | Not applicable | 1 |
| WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring)NCT07058064 · Rochester, Minnesota | Not applicable | 1 |
| Minibeam Radiation Therapy With Tungsten Slit Collimator for the Treatment of Recurrent or Metastatic Skin or Soft Tissue TumorsNCT07062003 · Rochester, Minnesota | Not applicable | 1 |
| Molecular and ctDNA Characterization of High-Risk Endometrial CancerNCT07062016 · Rochester, Minnesota | — | 1 |