| A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic MutationNCT05552157 · Birmingham, Alabama | Phase 2/3 | 13 |
| A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic MutationNCT06647498 · Birmingham, Alabama | Phase 2/3 | 13 |
| Multi-Institutional Registry for Malignant Peripheral Nerve Sheath TumorsNCT03141021 · Tampa, Florida | — | 9 |
| Dominantly Inherited Alzheimer Network (DIAN)NCT00869817 · Jacksonville, Florida | — | 8 |
| CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for AsthmaNCT07241117 · St Louis, Missouri | Phase 4 | 7 |
| Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal CancerNCT03516708 · Orange, California | Phase 1/2 | 4 |
| Zanzalintinib in Combination With Paclitaxel in Recurrent High Grade Uterine CancerNCT06795009 · San Francisco, California | Phase 1 | 4 |
| Uterine Preservation Via Lifestyle TransformationNCT05903131 · St Louis, Missouri | Phase 2 | 3 |
| Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone MetastasisNCT06374459 · Westwood, Kansas | Phase 1/2 | 3 |
| Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual DiseaseNCT06529822 · Orlando, Florida | Phase 1 | 3 |
| The Minimalist Trial-2NCT06702033 · St Louis, Missouri | Phase 2 | 3 |
| CARE Tool Study Aim 3NCT07296887 · Alton, Illinois | Not applicable | 3 |
| Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)NCT05277558 · St Louis, Missouri | — | 2 |
| Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal AdenocarcinomaNCT06141031 · Aurora, Colorado | Phase 1 | 2 |
| Feasibility and Acceptability of HCV Treatment in PregnancyNCT06367465 · St Louis, Missouri | — | 2 |
| Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)NCT06926634 · Rochester, Minnesota | Phase 2 | 2 |
| Precision Treatment to Promote Smoking Cessation and Survival in Oncology PatientsNCT07166120 · St Louis, Missouri | Not applicable | 2 |
| Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer CellsNCT00353483 · St Louis, Missouri | — | 1 |
| Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence ScoreNCT02476786 · St Louis, Missouri | Phase 2 | 1 |
| Computer-based Neurocognitive Assessment in Children With Central Nervous System Tumors Receiving Proton Beam Radiation TherapyNCT02559752 · St Louis, Missouri | — | 1 |
| Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical StudyNCT02841553 · St Louis, Missouri | — | 1 |
| Cognitive Biomarkers in Pediatric Brain Tumor PatientsNCT02914067 · St Louis, Missouri | Not applicable | 1 |
| NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain CircuitsNCT02994433 · St Louis, Missouri | Phase 1 | 1 |
| Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate BrachytherapyNCT03424850 · St Louis, Missouri | Phase 1/2 | 1 |
| Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System TumorsNCT03988283 · St Louis, Missouri | Phase 1 | 1 |
| Continuous Versus Intermittent cARdiac Electrical moNitorinGNCT04336644 · St Louis, Missouri | Not applicable | 1 |
| Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal CancerNCT04339374 · St Louis, Missouri | Not applicable | 1 |
| Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid TumorsNCT04354064 · St Louis, Missouri | — | 1 |
| Diffusion Basis Spectrum Imaging of the ProstateNCT04420702 · St Louis, Missouri | Not applicable | 1 |
| Fresh RX: NHS 2020NCT04845230 · St Louis, Missouri | Not applicable | 1 |
| Three Schedules of CUE-101 Administered Before Surgery or Definitive Chemoradiation Therapy in HLA-A*0201 Positive Patients With Locally Advanced, HPV16-Positive Oropharyngeal Squamous-Cell CarcinomaNCT04852328 · St Louis, Missouri | Phase 2 | 1 |
| Treatment Monitoring of Patients Receiving CDK 4/6 Inhibitors for Hormone Receptor (HR) Positive, HER2 Negative Metastatic Breast Cancer (MBC) With or Without the Addition of DiviTum® Serum Thymidine Kinase 1 (TK1) Activity TestingNCT04968964 · St Louis, Missouri | Not applicable | 1 |
| Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDSNCT04986657 · St Louis, Missouri | Not applicable | 1 |
| Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic MalignanciesNCT05011422 · St Louis, Missouri | Phase 1 | 1 |
| Utility of 18FDOPA PET/MRI for Focal HyperinsulinismNCT05088798 · St Louis, Missouri | Phase 2 | 1 |
| CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal CancerNCT05187182 · St Louis, Missouri | Phase 1 | 1 |
| Sonobiopsy for Noninvasive and Sensitive Detection of GlioblastomaNCT05281731 · St Louis, Missouri | Not applicable | 1 |
| Depression and DrivingNCT05446805 · St Louis, Missouri | — | 1 |
| Cryoablation vs Lumpectomy in T1 Breast CancersNCT05505643 · St Louis, Missouri | Not applicable | 1 |
| Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)NCT05521984 · St Louis, Missouri | Phase 1 | 1 |
| The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF)NCT05562167 · St Louis, Missouri | Phase 2 | 1 |
| Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer SurvivorsNCT05582551 · St Louis, Missouri | Not applicable | 1 |
| Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint InhibitorsNCT05629546 · St Louis, Missouri | Phase 1 | 1 |
| NeoTAILOR: ABiomarker-directed Approach to Guide Neoadjuvant Therapy for Patients With Stage II/III ER-positive, HER2-negative Breast CancerNCT05837455 · St Louis, Missouri | Phase 2 | 1 |
| Neurosurgical Neuronavigation Using Resting State MRI and Machine LearningNCT05864976 · St Louis, Missouri | — | 1 |
| Disruptions of Brain Networks and Sleep by Electroconvulsive TherapyNCT05905705 · St Louis, Missouri | — | 1 |
| Small Extracellular Vesicles and Insulin ActionNCT05933707 · St Louis, Missouri | Not applicable | 1 |
| COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical PatientsNCT05972343 · St Louis, Missouri | — | 1 |
| MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRialNCT05975593 · St Louis, Missouri | Not applicable | 1 |
| BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast CancerNCT05977036 · St Louis, Missouri | Not applicable | 1 |
| Parathyroid Tumor Clonal StatusNCT05997810 · St Louis, Missouri | — | 1 |
| Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1NCT06129838 · St Louis, Missouri | — | 1 |
| Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AMLNCT06158828 · St Louis, Missouri | Phase 1/2 | 1 |
| Radiation Induced Alterations in Resting State Brain Networks in Pediatric Brain Tumor PatientsNCT06185686 · St Louis, Missouri | — | 1 |
| Safety and Efficacy of CS1 CAR-T (WS-CART-CS1) in Subjects With Multiple MyelomaNCT06185751 · St Louis, Missouri | Phase 1 | 1 |
| Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)NCT06340646 · St Louis, Missouri | Not applicable | 1 |
| Beta Amyloid PET Imaging for Alzheimer Disease With [18F]-FluselenamylNCT06439992 · St Louis, Missouri | — | 1 |
| Propranolol for the Treatment of Kaposi Sarcoma in AdultsNCT06445166 · St Louis, Missouri | Phase 2 | 1 |
| Measurable Residual Disease-Guided Post-Transplant Elranatamab MaintenanceNCT06483100 · St Louis, Missouri | Phase 2 | 1 |
| Efficacy and Safety of a Ketogenic Diet in Type 1 DiabetesNCT06503809 · St Louis, Missouri | Not applicable | 1 |
| Impact of Recombinant Human Interleukin-7 (CYT107) on Tumor Clearance and Immune Reconstitution in Multiple Myeloma Patients After Autologous Hematopoietic Cell TransplantNCT06523699 · St Louis, Missouri | Phase 1 | 1 |
| Accelerated Brachytherapy Forward Chemo Radiation Therapy (ABC-RT) for Locally-advanced Cervical CancerNCT06529809 · St Louis, Missouri | Phase 1/2 | 1 |
| Study to Understand Novel Biomarkers in Researching DementiaNCT06547099 · St Louis, Missouri | — | 1 |
| Ultra-Hypofractionated vs. Hypofractionated Radiation for Node-Positive Breast CancerNCT06559540 · St Louis, Missouri | Phase 2 | 1 |
| Smoldering Inflammation in MSNCT06591429 · St Louis, Missouri | — | 1 |
| Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal FunctionNCT06623630 · St Louis, Missouri | Phase 1 | 1 |
| Window of Opportunity Study of DSP-0390 in GliomasNCT06636162 · St Louis, Missouri | Early phase 1 | 1 |
| 64Cu-LLP2A for Imaging Hematologic MalignanciesNCT06636175 · St Louis, Missouri | Early phase 1 | 1 |
| MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal AdenocarcinomaNCT06648434 · St Louis, Missouri | Phase 1 | 1 |
| CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based Autologous Stem Cell TransplantNCT06687772 · St Louis, Missouri | Phase 2 | 1 |
| Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular TherapyNCT06689800 · St Louis, Missouri | Not applicable | 1 |
| Precision Imaging to Evaluate Kaposi Sarcoma (PRIME-KS): A Device Feasibility TrialNCT06751355 · St Louis, Missouri | — | 1 |
| Role of KATP Channel Loss in Type 2 DiabetesNCT06830096 · St Louis, Missouri | Not applicable | 1 |
| Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed GlioblastomaNCT06831526 · St Louis, Missouri | Early phase 1 | 1 |
| WashU DIEP Flap Video and Patient Understanding ImprovementNCT06864754 · St Louis, Missouri | Not applicable | 1 |
| Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) Stage IINCT06867549 · St Louis, Missouri | Phase 2 | 1 |
| Implementation and Effectiveness of the BJC-Pink and Pearl Project on Lung Cancer ScreeningNCT06898333 · Creve Coeur, Missouri | — | 1 |
| ONT01 and Gemcitabine/Nab-paclitaxel as Second Line Therapy for Metastatic Pancreatic Ductal AdenocarcinomaNCT06904378 · St Louis, Missouri | Phase 1/2 | 1 |
| Implementing a Randomized Control Trial to Test the Expanded Web-based Decision AidNCT06910670 · St Louis, Missouri | Not applicable | 1 |
| Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and LeiomyosarcomaNCT06957431 · St Louis, Missouri | Phase 1 | 1 |
| Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue SarcomaNCT06968988 · St Louis, Missouri | Phase 1 | 1 |
| Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac SurgeryNCT06969287 · St Louis, Missouri | Phase 3 | 1 |
| Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic PainNCT06978166 · St Louis, Missouri | Not applicable | 1 |
| ChatGPT & Surgeon Synergy: Redefining Breast Reconstruction Consultations for Enhanced Patient Engagement and SatisfactionNCT06981208 · St Louis, Missouri | Not applicable | 1 |
| Neuroimaging of Parkinson'sNCT07024875 · St Louis, Missouri | — | 1 |
| Mindfulness to Enhance Cognitive Health in Latino Older AdultsNCT07040904 · St Louis, Missouri | Not applicable | 1 |
| NT-I7 (Efineptakin Alfa), a Long-acting Human IL-7, Post-Axicabtagene Ciloleucel or Post-Lisocabtagene Maraleucel in Subjects With Relapsed/Refractory Large B-cell LymphomaNCT07052305 · St Louis, Missouri | Phase 1 | 1 |
| Lenvatinib 24 mg/Day Versus 10 mg/Day to Treat Symptomatic or Progressive Radioactive Iodine Resistant (RAIR) Differentiated Thyroid Cancer (DTC)NCT07092514 · St Louis, Missouri | Phase 2 | 1 |
| Adolescent ChatbotNCT07094503 · St Louis, Missouri | Phase 2 | 1 |
| Effect of Ketone Esters on Liver Fat Content and Metabolic FunctionNCT07097506 · St Louis, Missouri | Phase 2 | 1 |
| Emavusertib (CA-4948) in Combination With Cisplatin, Gemcitabine, and Durvalumab in Patients With Untreated Advanced or Metastatic Biliary Tract CancerNCT07107750 · St Louis, Missouri | Phase 1 | 1 |
| Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health SystemNCT07109427 · St Louis, Missouri | Not applicable | 1 |
| This Study Involves a Positron Emission Tomography (PET) Scan Using a New Investigational Radioactive Tracer, [18F]-FZTA, to Detect Inflammation in the Brain. The Tracer Will be Tested in Healthy Younger Adults and Individuals With Multiple Sclerosis.NCT07115017 · St Louis, Missouri | — | 1 |
| Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic AdenocarcinomaNCT07126158 · St Louis, Missouri | Phase 2 | 1 |
| Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung Cancer Screening at Christian HospitalNCT07146568 · St Louis, Missouri | Not applicable | 1 |
| Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)NCT07155200 · St Louis, Missouri | Phase 1/2 | 1 |
| Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel)NCT07200089 · St Louis, Missouri | Phase 1 | 1 |
| Selinexor Maintenance Post CAR-T Cell Therapy for Multiple MyelomaNCT07200102 · St Louis, Missouri | Phase 1 | 1 |
| Pain in Juvenile ArthritisNCT07217782 · St Louis, Missouri | Not applicable | 1 |
| Low-Count Quantitative SPECT for Men Treated With Radium-223NCT07221825 · St Louis, Missouri | Not applicable | 1 |
| An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic CancersNCT07226934 · St Louis, Missouri | Not applicable | 1 |
| Cancer Care CompanionNCT07278778 · St Louis, Missouri | Not applicable | 1 |
| INCLUDE Program: A Perioperative Wellness Program Tailored for Black Surgical PatientsNCT07283783 · St Louis, Missouri | Not applicable | 1 |
| Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) PatientsNCT07313592 · St Louis, Missouri | — | 1 |
| First-Line Ipilimumab Plus Nivolumab and Nogapendekin Alfa Inbakicept (N-803) in Patients With Stage IV or Recurrent Non-Small Cell Lung CancerNCT07355205 · St Louis, Missouri | Phase 1/2 | 1 |
| Patient Position Monitoring System for Beam Gated Radiation Therapy of Malignancies of the Chest and Upper AbdomenNCT07373496 · St Louis, Missouri | — | 1 |
| Therapeutic RSK1 Targeting in MyelofibrosisNCT07379125 · St Louis, Missouri | Phase 1 | 1 |
| Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent GlioblastomaNCT07392957 · St Louis, Missouri | Phase 1/2 | 1 |
| Motixafortide for MRD Sensitization in AMLNCT07392970 · St Louis, Missouri | Phase 2 | 1 |
| 5-Fluorouracil Response and Optimization STudy (The FROST Trial)NCT07419464 · St Louis, Missouri | Phase 2 | 1 |
| Feasibility of HPV Self-Collection Kits for Cervical Cancer ScreeningNCT07453459 · St Louis, Missouri | Not applicable | 1 |
| Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1NCT07462507 · St Louis, Missouri | Phase 2 | 1 |
| Leveraging mHealth to Promote Opioid Use Recovery and Mental Health Among Residents of a Medium-Sized Midwestern CityNCT07673380 · St Louis, Missouri | Phase 2 | 1 |