Heart Disease Clinical Trials in Cleveland, OH

135 recruiting studies within 50 miles

Phase

Trial	Phase	Sponsor	Dist.
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity	Phase 3	SWOG Cancer Research Network	<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products	—	Medtronic	<1 mi
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	—	Columbia University	<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery	Phase 3	Yale University	<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease	—	Children's Hospital Medical Center, Cincinnati	<1 mi
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy	—	Tenaya Therapeutics	<1 mi
CV Imaging of Metabolic Interventions	—	The Cleveland Clinic	<1 mi
The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial	Phase 4	VA Office of Research and Development	<1 mi
Product Surveillance Registry	—	Medtronic	<1 mi
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC	Phase 1	Tenaya Therapeutics	<1 mi
Wearable Technology in Heart Failure Patients	—	The Cleveland Clinic	<1 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)	Phase 3	Boehringer Ingelheim	<1 mi
Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study	—	Centre hospitalier de l'Université de Montréal (CHUM)	<1 mi
Assessment of CCM in HF With Higher Ejection Fraction	N/A	Impulse Dynamics	<1 mi
Left vs Left Randomized Clinical Trial	N/A	Baylor College of Medicine	<1 mi
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)	—	Tenaya Therapeutics	<1 mi
Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease	N/A	Population Health Research Institute	<1 mi
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting	—	Corcym S.r.l	<1 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE	—	Medtronic Cardiovascular	<1 mi
Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic	—	The Cleveland Clinic	<1 mi
Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers	—	University of Texas Southwestern Medical Center	<1 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels	N/A	Concept Medical Inc.	<1 mi
Intracardiac Echocardiography Guided Watchman Device Implant	N/A	The Cleveland Clinic	<1 mi
BoxX-NoAF Clinical Trial	N/A	AtriCure, Inc.	<1 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant	Phase 3	Eidos Therapeutics, a BridgeBio company	<1 mi
CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)	Phase 3	Cardiol Therapeutics Inc.	<1 mi
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II	N/A	Shockwave Medical, Inc.	<1 mi
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™	N/A	JenaValve Technology, Inc.	<1 mi
Medtronic Cardiac Surgery PMCF Registry	—	Medtronic Cardiac Surgery	<1 mi
Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease	—	The Cleveland Clinic	<1 mi
CTSN Embolic Protection Trial	N/A	Icahn School of Medicine at Mount Sinai	<1 mi
Pulsed Field Ablation for Post-Infarction Ventricular Tachycardia	N/A	Pasquale Santangeli	<1 mi
Phase 2/3 Study of KPL-387 in Recurrent Pericarditis	Phase 2/3	Kiniksa Pharmaceuticals International, plc	<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction	Phase 3	Cytokinetics	<1 mi
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)	Phase 3	NYU Langone Health	<1 mi
A Cardiac Disease Quality of Life Study	—	The Cleveland Clinic	<1 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study	Phase 2/3	Kardigan, Inc.	<1 mi
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)	Phase 3	Novartis Pharmaceuticals	<1 mi
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease	Phase 3	Alessandro Doria	<1 mi
Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)	N/A	VahatiCor, Inc.	<1 mi
The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study	N/A	Half Moon Medical	<1 mi
Trisol System EFS Study	N/A	Trisol Medical	<1 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS	Phase 3	DalCor Pharmaceuticals	<1 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions	N/A	Concept Medical Inc.	<1 mi
Project 3: ACHIEVE- CHD	N/A	University Hospitals Cleveland Medical Center	<1 mi
Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment	—	Montefiore Medical Center	<1 mi
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation	N/A	University of Pennsylvania	<1 mi
Cephea Early Feasibility Study	N/A	Abbott Medical Devices	<1 mi
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve	N/A	Edwards Lifesciences	<1 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections	Phase 3	X4 Pharmaceuticals	<1 mi
Abatacept in Immune Checkpoint Inhibitor Myocarditis	Phase 3	Massachusetts General Hospital	<1 mi
The Effect of Womb Recordings on Maturation of Respiratory Control in Preterm Infants	N/A	Case Western Reserve University	<1 mi
Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables	—	The Cleveland Clinic	<1 mi
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)	Phase 3	Intellia Therapeutics	<1 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart	Phase 3	Boehringer Ingelheim	<1 mi
Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF	—	The Cleveland Clinic	<1 mi
AltaValve Pivotal Trial	N/A	4C Medical Technologies, Inc.	<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)	N/A	Biosense Webster, Inc.	<1 mi
The Fourth Left Atrial Appendage Occlusion Study	N/A	Hamilton Health Sciences Corporation	<1 mi
Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation	N/A	Arga Medtech SA	<1 mi
PARTNER 3 Trial - Aortic Valve-in-Valve	N/A	Edwards Lifesciences	<1 mi
Low Voltage-Directed Catheter Ablation for Atrial Fibrillation	N/A	Ohad Ziv	<1 mi
Randomization of Single vs Multiple Arterial Grafts	N/A	Weill Medical College of Cornell University	<1 mi
PRIMARY Ancillary Substudy	N/A	Annetine Gelijns	<1 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR	N/A	Cardiac Dimensions, Inc.	<1 mi
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM	Phase 1/2	Tenaya Therapeutics	<1 mi
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction	Phase 3	Bayer	<1 mi
Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"	N/A	NHS Greater Glasgow and Clyde	<1 mi
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass	Phase 3	Octapharma	<1 mi
A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation	N/A	Boston Scientific Corporation	<1 mi
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III	N/A	Endotronix, Inc.	<1 mi
The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study	N/A	Brigham and Women's Hospital	<1 mi
Patient-Centered Approach for Treatment Decisions in Mitral Valve Prolapse	—	Northwell Health	<1 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)	—	Bristol-Myers Squibb	<1 mi
Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR	N/A	EnCompass Technologies, Inc.	<1 mi
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure	N/A	BrioHealth Solutions, Inc.	<1 mi
Development of CIRC Technologies	—	The Cleveland Clinic	<1 mi
TVMR With the INNOVALVE System Trial - Early Feasibility Study	N/A	Edwards Lifesciences	<1 mi
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes	Phase 4	VA Office of Research and Development	<1 mi
TTVR Early Feasibility Study	N/A	Medtronic Cardiovascular	<1 mi
LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions	Phase 4	Yale University	<1 mi
HCMR Re-Imaging Study	—	Christopher Kramer	<1 mi
Fluid Guided Heart Failure Treatment at the Cleveland Clinic	N/A	Bodyport Inc.	<1 mi
Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution	—	The Cleveland Clinic	<1 mi
MRI in Transcatheter Aortic Valve Replacement Patients	N/A	University Hospitals Cleveland Medical Center	<1 mi
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions	N/A	Boston Scientific Corporation	<1 mi
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity	Phase 3	Novo Nordisk A/S	<1 mi
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)	N/A	P+F Products + Features USA Inc.	<1 mi
Tracking Results of Ablations to Combat AF Registry Generation 2	—	AtriCure, Inc.	<1 mi
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation	Phase 2	The Cleveland Clinic	<1 mi
ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)	—	Emory University	<1 mi
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy	Phase 3	Alnylam Pharmaceuticals	<1 mi
EFS of the CardioMech MVRS	N/A	CardioMech AS	<1 mi
The ENCIRCLE Trial	N/A	Edwards Lifesciences	<1 mi
Dietary Tracking in Heart Failure	—	The Cleveland Clinic	<1 mi
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance	—	Minneapolis Heart Institute Foundation	<1 mi
Prevail Global Study	N/A	Medtronic Vascular	<1 mi
Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):	N/A	The Cleveland Clinic	<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy	Phase 4	Dennis M. McNamara, MD, MS	<1 mi
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)	Phase 2/3	Merck Sharp & Dohme LLC	<1 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy	Phase 3	Lexicon Pharmaceuticals	<1 mi
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis	—	Columbia University	<1 mi
Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) Study	Phase 4	The Cleveland Clinic	<1 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG	Phase 3	Icahn School of Medicine at Mount Sinai	<1 mi
Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) Study	N/A	AtaCor Medical, Inc.	<1 mi
Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF	—	The Cleveland Clinic	<1 mi
ATrial Tachycardia PAcing Therapy in Congenital Heart	—	Ian Law	<1 mi
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)	Phase 1	Solid Biosciences Inc.	<1 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure	N/A	Abbott Medical Devices	<1 mi
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients	Phase 4	University of Rochester	<1 mi
An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis	Phase 2	Zomagen Biosciences Ltd.	<1 mi
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves	N/A	Edwards Lifesciences	<1 mi
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction	Phase 3	Bayer	<1 mi
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM	—	Cordio Medical	<1 mi
Comparative Imaging Assessment of Valvular Heart Disease	—	The Cleveland Clinic	<1 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.	N/A	Medtronic Cardiovascular	<1 mi
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)	N/A	Sunnybrook Health Sciences Centre	<1 mi
A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure	N/A	Tufts Medical Center	<1 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women	N/A	Weill Medical College of Cornell University	<1 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2	Phase 3	Mezzion Pharma Co. Ltd	<1 mi
Sternal Plating High Risk	N/A	University Hospitals Cleveland Medical Center	<1 mi
Abbott Cephea Mitral Valve Disease Registry	—	Abbott Medical Devices	<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy	Phase 3	Pierre Fabre Medicament	<1 mi
A Nurse-Led Weight Monitoring Intervention For Heart Failure Quality of LIfe and Self-Care	N/A	Lee Anne Siegmund	18 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events	N/A	Cleerly, Inc.	30 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative	—	Children's Hospital of Philadelphia	30 mi
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists	Phase 3	Colorado Prevention Center	30 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment	—	Children's Oncology Group	30 mi
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients	Phase 3	Colorado Prevention Center	30 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)	N/A	University of Michigan	30 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement	N/A	University of British Columbia	30 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation	Phase 3	Johns Hopkins University	50 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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