Heart Disease Clinical Trials in Cleveland, OH

126 recruiting studies within 50 miles

Phase

Trial	Phase	Sponsor	Dist.
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity	Phase 3	SWOG Cancer Research Network	<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery	Phase 3	Yale University	<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease	—	Children's Hospital Medical Center, Cincinnati	<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products	—	Medtronic	<1 mi
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	—	Columbia University	<1 mi
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy	—	Tenaya Therapeutics	<1 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions	N/A	Concept Medical Inc.	<1 mi
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure	N/A	BrioHealth Solutions, Inc.	<1 mi
Prevail Global Study	N/A	Medtronic Vascular	<1 mi
LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions	Phase 4	Yale University	<1 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2	Phase 3	Mezzion Pharma Co. Ltd	<1 mi
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)	N/A	Annetine Gelijns	<1 mi
PRIMARY Ancillary Substudy	N/A	Annetine Gelijns	<1 mi
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation	Phase 2	The Cleveland Clinic	<1 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS	Phase 3	DalCor Pharmaceuticals	<1 mi
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease	Phase 3	Alessandro Doria	<1 mi
The ENCIRCLE Trial	N/A	Edwards Lifesciences	<1 mi
Development of CIRC Technologies	—	The Cleveland Clinic	<1 mi
Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment	—	Montefiore Medical Center	<1 mi
Phase 2/3 Study of KPL-387 in Recurrent Pericarditis	Phase 2/3	Kiniksa Pharmaceuticals International, plc	<1 mi
CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)	Phase 3	Cardiol Therapeutics Inc.	<1 mi
MRI in Transcatheter Aortic Valve Replacement Patients	N/A	University Hospitals Cleveland Medical Center	<1 mi
AltaValve Pivotal Trial	N/A	4C Medical Technologies, Inc.	<1 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure	N/A	Abbott Medical Devices	<1 mi
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves	N/A	Edwards Lifesciences	<1 mi
Left vs Left Randomized Clinical Trial	N/A	Baylor College of Medicine	<1 mi
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC	Phase 1	Tenaya Therapeutics	<1 mi
Medtronic Cardiac Surgery PMCF Registry	—	Medtronic Cardiac Surgery	<1 mi
ATrial Tachycardia PAcing Therapy in Congenital Heart	—	Ian Law	<1 mi
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM	Phase 1/2	Tenaya Therapeutics	<1 mi
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions	N/A	Boston Scientific Corporation	<1 mi
Randomization of Single vs Multiple Arterial Grafts	N/A	Weill Medical College of Cornell University	<1 mi
Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):	N/A	The Cleveland Clinic	<1 mi
A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation	N/A	Boston Scientific Corporation	<1 mi
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting	—	Corcym S.r.l	<1 mi
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections	Phase 3	X4 Pharmaceuticals	<1 mi
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)	Phase 3	Intellia Therapeutics	<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)	N/A	Biosense Webster, Inc.	<1 mi
CTSN Embolic Protection Trial	N/A	Icahn School of Medicine at Mount Sinai	<1 mi
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy	Phase 3	Alnylam Pharmaceuticals	<1 mi
Assessment of CCM in HF With Higher Ejection Fraction	N/A	Impulse Dynamics	<1 mi
Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease	—	The Cleveland Clinic	<1 mi
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction	Phase 3	Bayer	<1 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart	Phase 3	Boehringer Ingelheim	<1 mi
Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"	N/A	NHS Greater Glasgow and Clyde	<1 mi
Patient-Centered Approach for Treatment Decisions in Mitral Valve Prolapse	—	Northwell Health	<1 mi
BoxX-NoAF Clinical Trial	N/A	AtriCure, Inc.	<1 mi
Abbott Cephea Mitral Valve Disease Registry	—	Abbott Medical Devices	<1 mi
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)	Phase 3	NYU Langone Health	<1 mi
Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution	—	The Cleveland Clinic	<1 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women	N/A	Weill Medical College of Cornell University	<1 mi
TTVR Early Feasibility Study	N/A	Medtronic Cardiovascular	<1 mi
Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic	—	The Cleveland Clinic	<1 mi
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis	—	Columbia University	<1 mi
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM	—	Cordio Medical	<1 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study	Phase 2/3	Kardigan, Inc.	<1 mi
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III	N/A	Endotronix, Inc.	<1 mi
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study	N/A	Ancora Heart, Inc.	<1 mi
Project 3: ACHIEVE- CHD	N/A	University Hospitals Cleveland Medical Center	<1 mi
Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study	—	Centre hospitalier de l'Université de Montréal (CHUM)	<1 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy	Phase 3	Lexicon Pharmaceuticals	<1 mi
Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance	—	Minneapolis Heart Institute Foundation	<1 mi
Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation	N/A	Arga Medtech SA	<1 mi
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation	N/A	University of Pennsylvania	<1 mi
Pulsed Field Ablation for Post-Infarction Ventricular Tachycardia	N/A	Pasquale Santangeli	<1 mi
Abatacept in Immune Checkpoint Inhibitor Myocarditis	Phase 3	Massachusetts General Hospital	<1 mi
EFS of the CardioMech MVRS	N/A	CardioMech AS	<1 mi
An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis	Phase 2	Zomagen Biosciences Ltd.	<1 mi
Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers	—	University of Texas Southwestern Medical Center	<1 mi
Low Voltage-Directed Catheter Ablation for Atrial Fibrillation	N/A	Ohad Ziv	<1 mi
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)	—	Tenaya Therapeutics	<1 mi
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)	N/A	Sunnybrook Health Sciences Centre	<1 mi
Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF	—	The Cleveland Clinic	<1 mi
Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF	—	The Cleveland Clinic	<1 mi
The Effect of Womb Recordings on Maturation of Respiratory Control in Preterm Infants	N/A	Case Western Reserve University	<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction	Phase 3	Cytokinetics	<1 mi
Cephea Early Feasibility Study	N/A	Abbott Medical Devices	<1 mi
Comparative Imaging Assessment of Valvular Heart Disease	—	The Cleveland Clinic	<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy	Phase 4	Dennis M. McNamara, MD, MS	<1 mi
Intracardiac Echocardiography Guided Watchman Device Implant	N/A	The Cleveland Clinic	<1 mi
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II	N/A	Shockwave Medical, Inc.	<1 mi
TVMR With the INNOVALVE System Trial - Early Feasibility Study	N/A	Edwards Lifesciences	<1 mi
A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure	N/A	Tufts Medical Center	<1 mi
The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study	N/A	Half Moon Medical	<1 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels	N/A	Concept Medical Inc.	<1 mi
The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study	N/A	Brigham and Women's Hospital	<1 mi
Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease	N/A	Population Health Research Institute	<1 mi
Trisol System EFS Study	N/A	Trisol Medical	<1 mi
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)	Phase 1	Solid Biosciences Inc.	<1 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.	N/A	Medtronic Cardiovascular	<1 mi
A Cardiac Disease Quality of Life Study	—	The Cleveland Clinic	<1 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)	Phase 3	Boehringer Ingelheim	<1 mi
The Fourth Left Atrial Appendage Occlusion Study	N/A	Hamilton Health Sciences Corporation	<1 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG	Phase 3	Icahn School of Medicine at Mount Sinai	<1 mi
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)	Phase 2	Merck Sharp & Dohme LLC	<1 mi
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass	Phase 3	Octapharma	<1 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE	—	Medtronic Cardiovascular	<1 mi
Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables	—	The Cleveland Clinic	<1 mi
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes	Phase 4	VA Office of Research and Development	<1 mi
Product Surveillance Registry	—	Medtronic	<1 mi
Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) Study	Phase 4	The Cleveland Clinic	<1 mi
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients	Phase 4	University of Rochester	<1 mi
PARTNER 3 Trial - Aortic Valve-in-Valve	N/A	Edwards Lifesciences	<1 mi
Tracking Results of Ablations to Combat AF Registry Generation 2	—	AtriCure, Inc.	<1 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR	N/A	Cardiac Dimensions, Inc.	<1 mi
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)	Phase 2/3	Merck Sharp & Dohme LLC	<1 mi
Sternal Plating High Risk	N/A	University Hospitals Cleveland Medical Center	<1 mi
Fluid Guided Heart Failure Treatment at the Cleveland Clinic	N/A	Bodyport Inc.	<1 mi
HCMR Re-Imaging Study	—	Christopher Kramer	<1 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)	—	Bristol-Myers Squibb	<1 mi
The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial	Phase 4	VA Office of Research and Development	<1 mi
CV Imaging of Metabolic Interventions	—	The Cleveland Clinic	<1 mi
Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR	N/A	EnCompass Technologies, Inc.	<1 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant	Phase 3	Eidos Therapeutics, a BridgeBio company	<1 mi
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)	N/A	P+F Products + Features USA Inc.	<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy	Phase 3	Pierre Fabre Medicament	<1 mi
A Nurse-Led Weight Monitoring Intervention For Heart Failure Quality of LIfe and Self-Care	N/A	Lee Anne Siegmund	18 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement	N/A	University of British Columbia	30 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative	—	Children's Hospital of Philadelphia	30 mi
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients	Phase 3	Colorado Prevention Center	30 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events	N/A	Cleerly, Inc.	30 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment	—	Children's Oncology Group	30 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)	N/A	University of Michigan	30 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation	Phase 3	Johns Hopkins University	50 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.