Heart Disease Clinical Trials in Ohio

193 recruiting studies across 2 cities

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All Trials in Ohio

Phase
Trial Phase Dist.
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and RecoveryPhase 3<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease<1 mi
Product Surveillance Registry<1 mi
Assessment of CCM in HF With Higher Ejection FractionN/A<1 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE<1 mi
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina IIN/A<1 mi
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™N/A<1 mi
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)Phase 3<1 mi
Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)N/A<1 mi
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)Phase 3<1 mi
Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial FibrillationN/A<1 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMRN/A<1 mi
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic DysfunctionPhase 3<1 mi
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary BypassPhase 3<1 mi
A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial FibrillationN/A<1 mi
The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States StudyN/A<1 mi
Trial of the F2 Filter and Delivery System for Embolic Protection During TAVRN/A<1 mi
TVMR With the INNOVALVE System Trial - Early Feasibility StudyN/A<1 mi
TTVR Early Feasibility StudyN/A<1 mi
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary LesionsN/A<1 mi
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)N/A<1 mi
The ENCIRCLE TrialN/A<1 mi
Prevail Global StudyN/A<1 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABGPhase 3<1 mi
Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) StudyN/A<1 mi
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)N/A<1 mi
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic DysfunctionPhase 3<1 mi
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM<1 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.N/A<1 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in WomenN/A<1 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2Phase 3<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and ChemotherapyPhase 3<1 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative<1 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)N/A<1 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve ReplacementN/A<1 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial FibrillationPhase 3<1 mi
PULSED AF Post-Approval Study<1 mi
EFS of the DUO System for Tricuspid RegurgitationN/A<1 mi
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation SystemN/A<1 mi
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE StudyN/A<1 mi
Pathways to Prevention Food-is-Medicine TrialN/A<1 mi
Genetics of Congenital Heart Disease<1 mi
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionN/A<1 mi
Effects of CPAP Therapy on Blood Pressure and Heart Rate Variability in Obstructive Sleep Apnea<1 mi
ELEVATE-HFpEF Clinical StudyN/A<1 mi
A Study of SGT-212 Gene Therapy in Friedreich's AtaxiaPhase 1<1 mi
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - WomenPhase 3<1 mi
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight InfantsN/A<1 mi
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEmN/A<1 mi
Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation<1 mi
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular GraftsPhase 2<1 mi
Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate CancerPhase 2<1 mi
IPSC Repository of Pediatric Cardiovascular Disease<1 mi
Cord Clamping Among Neonates With Congenital Heart DiseaseN/A<1 mi
The CONFORM Pivotal TrialN/A<1 mi
Cardiac Sarcoidosis Randomized TrialPhase 3<1 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With DapagliflozinPhase 3<1 mi
Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)N/A<1 mi
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF StudyN/A<1 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical TrialN/A<1 mi
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)Phase 2/3<1 mi
Pivotal Study for the Cardiac Performance System (CPS)<1 mi
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry<1 mi
Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac FunctionN/A<1 mi
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma<1 mi
Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)<1 mi
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular RiskPhase 3<1 mi
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve StenosisPhase 2<1 mi
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart FailureN/A<1 mi
Ketogenic Diet vs Mixed Diet in Patients With Heart FailureN/A<1 mi
Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias<1 mi
Minima Stent System Post- Approval Study (PAS)<1 mi
Abbott Vascular Medical Device Registry<1 mi
Congenital Heart Disease Physical Activity Lifestyle Study V.2N/A<1 mi
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart FailurePhase 4<1 mi
The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative DeliriumPhase 3<1 mi
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVRN/A<1 mi
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - MinoritiesPhase 3<1 mi
Effect of Fetal Aortic Valvuloplasty on Outcomes<1 mi
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension SystemN/A<1 mi
Optimal Ventilation for Cardiac ArrestN/A<1 mi
LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEFPhase 3<1 mi
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart FailureN/A<1 mi
Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)N/A<1 mi
Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease<1 mi
Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials<1 mi
Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues<1 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac ToxicityPhase 3<1 mi
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)<1 mi
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy<1 mi
CV Imaging of Metabolic Interventions<1 mi
The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) TrialPhase 4<1 mi
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVCPhase 1<1 mi
Wearable Technology in Heart Failure Patients<1 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)Phase 3<1 mi
Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study<1 mi
Left vs Left Randomized Clinical TrialN/A<1 mi
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)<1 mi
Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel DiseaseN/A<1 mi
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting<1 mi
Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic<1 mi
Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers<1 mi
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small VesselsN/A<1 mi
Intracardiac Echocardiography Guided Watchman Device ImplantN/A<1 mi
BoxX-NoAF Clinical TrialN/A<1 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR VariantPhase 3<1 mi
CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)Phase 3<1 mi
Medtronic Cardiac Surgery PMCF Registry<1 mi
Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease<1 mi
CTSN Embolic Protection TrialN/A<1 mi
Pulsed Field Ablation for Post-Infarction Ventricular TachycardiaN/A<1 mi
Phase 2/3 Study of KPL-387 in Recurrent PericarditisPhase 2/3<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection FractionPhase 3<1 mi
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)Phase 3<1 mi
A Cardiac Disease Quality of Life Study<1 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled StudyPhase 2/3<1 mi
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney DiseasePhase 3<1 mi
Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)N/A<1 mi
The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot StudyN/A<1 mi
Trisol System EFS StudyN/A<1 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACSPhase 3<1 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery LesionsN/A<1 mi
Project 3: ACHIEVE- CHDN/A<1 mi
Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment<1 mi
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device ImplantationN/A<1 mi
Cephea Early Feasibility StudyN/A<1 mi
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart ValveN/A<1 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious InfectionsPhase 3<1 mi
Abatacept in Immune Checkpoint Inhibitor MyocarditisPhase 3<1 mi
The Effect of Womb Recordings on Maturation of Respiratory Control in Preterm InfantsN/A<1 mi
Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables<1 mi
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the HeartPhase 3<1 mi
Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF<1 mi
AltaValve Pivotal TrialN/A<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)N/A<1 mi
The Fourth Left Atrial Appendage Occlusion StudyN/A<1 mi
PARTNER 3 Trial - Aortic Valve-in-ValveN/A<1 mi
Low Voltage-Directed Catheter Ablation for Atrial FibrillationN/A<1 mi
Randomization of Single vs Multiple Arterial GraftsN/A<1 mi
PRIMARY Ancillary SubstudyN/A<1 mi
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCMPhase 1/2<1 mi
Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"N/A<1 mi
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and IIIN/A<1 mi
Patient-Centered Approach for Treatment Decisions in Mitral Valve Prolapse<1 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)<1 mi
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart FailureN/A<1 mi
Development of CIRC Technologies<1 mi
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomesPhase 4<1 mi
LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic ConditionsPhase 4<1 mi
HCMR Re-Imaging Study<1 mi
Fluid Guided Heart Failure Treatment at the Cleveland ClinicN/A<1 mi
Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution<1 mi
MRI in Transcatheter Aortic Valve Replacement PatientsN/A<1 mi
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and ObesityPhase 3<1 mi
Tracking Results of Ablations to Combat AF Registry Generation 2<1 mi
TIRzepatide for the Treatment of Obesity in Patients With Atrial FibrillationPhase 2<1 mi
ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)<1 mi
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With CardiomyopathyPhase 3<1 mi
EFS of the CardioMech MVRSN/A<1 mi
Dietary Tracking in Heart Failure<1 mi
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)N/A<1 mi
Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance<1 mi
Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):N/A<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum CardiomyopathyPhase 4<1 mi
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)Phase 2/3<1 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic CardiomyopathyPhase 3<1 mi
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis<1 mi
Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) StudyPhase 4<1 mi
Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF<1 mi
ATrial Tachycardia PAcing Therapy in Congenital Heart<1 mi
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)Phase 1<1 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart FailureN/A<1 mi
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) PatientsPhase 4<1 mi
An Open-Label Pilot Study of VTX2735 in Recurrent PericarditisPhase 2<1 mi
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic ValvesN/A<1 mi
Comparative Imaging Assessment of Valvular Heart Disease<1 mi
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)N/A<1 mi
A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart FailureN/A<1 mi
Sternal Plating High RiskN/A<1 mi
Abbott Cephea Mitral Valve Disease Registry<1 mi
A Nurse-Led Weight Monitoring Intervention For Heart Failure Quality of LIfe and Self-CareN/A18 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular EventsN/A30 mi
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor AntagonistsPhase 330 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment30 mi
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure PatientsPhase 330 mi
A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter SystemN/A43 mi
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney FunctionPhase 343 mi
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular InterventionPhase 443 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular EventsPhase 344 mi
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is UnsuitablePhase 344 mi
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart FailurePhase 344 mi
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With AnticoagulationPhase 244 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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