Heart Disease Clinical Trials in Massachusetts

214 recruiting studies across 1 city

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All Trials in Massachusetts

Phase

Trial	Phase	Sponsor	Dist.
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function	Phase 3	AstraZeneca	<1 mi
Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System	N/A	Boston Scientific Corporation	<1 mi
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis	Phase 2/3	CSL Behring	<1 mi
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement	N/A	University of British Columbia	<1 mi
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions	N/A	Boston Scientific Corporation	<1 mi
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery	Phase 3	Yale University	<1 mi
SELUTION 4 De Novo Small Vessel IDE Trial	N/A	M.A. Med Alliance S.A.	<1 mi
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study	N/A	Ancora Heart, Inc.	<1 mi
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients	Phase 3	Colorado Prevention Center	<1 mi
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy	Phase 4	Dennis M. McNamara, MD, MS	<1 mi
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment	—	Children's Oncology Group	<1 mi
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation	Phase 3	Johns Hopkins University	<1 mi
LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF	Phase 3	Tenax Therapeutics, Inc.	<1 mi
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)	—	Duke University	<1 mi
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin	Phase 3	AstraZeneca	<1 mi
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions	N/A	Concept Medical Inc.	<1 mi
Reducing Risk for Infective Endocarditis	N/A	Wake Forest University Health Sciences	<1 mi
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure	N/A	BrioHealth Solutions, Inc.	<1 mi
LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions	Phase 4	Yale University	<1 mi
Real-world Patient Reported Outcomes Among Patients Treated With Camzyos	—	Bristol-Myers Squibb	<1 mi
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2	Phase 3	Mezzion Pharma Co. Ltd	<1 mi
Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block	—	The Hospital for Sick Children	<1 mi
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)	N/A	Annetine Gelijns	<1 mi
Care Transitions App for Patients With Multiple Chronic Conditions	N/A	Brigham and Women's Hospital	<1 mi
PRIMARY Ancillary Substudy	N/A	Annetine Gelijns	<1 mi
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study	N/A	Starlight Cardiovascular Inc	<1 mi
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease	Phase 3	Alessandro Doria	<1 mi
Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation	—	Heart Rhythm Clinical and Research Solutions, LLC	<1 mi
DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting	—	Alnylam Pharmaceuticals	<1 mi
The ENCIRCLE Trial	N/A	Edwards Lifesciences	<1 mi
Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure	—	Massachusetts General Hospital	<1 mi
Phase 2/3 Study of KPL-387 in Recurrent Pericarditis	Phase 2/3	Kiniksa Pharmaceuticals International, plc	<1 mi
CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)	Phase 3	Cardiol Therapeutics Inc.	<1 mi
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets	—	Northwestern University	<1 mi
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease	Phase 2	Rocket Pharmaceuticals Inc.	<1 mi
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension	Phase 2	Retension Pharmaceuticals. Inc.	<1 mi
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure	N/A	Abbott Medical Devices	<1 mi
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves	N/A	Edwards Lifesciences	<1 mi
Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst	—	Boston Medical Center	<1 mi
Left vs Left Randomized Clinical Trial	N/A	Baylor College of Medicine	<1 mi
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis	Phase 2	Novartis Pharmaceuticals	<1 mi
Allogeneic Valve Transplantation	N/A	Boston Children's Hospital	<1 mi
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC	Phase 1	Tenaya Therapeutics	<1 mi
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study	N/A	Massachusetts General Hospital	<1 mi
Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children	—	Boston Children's Hospital	<1 mi
Assessing the Burden of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery	—	Brigham and Women's Hospital	<1 mi
The STOP-MED CTRCD Trial	Phase 4	Dinesh Thavendiranathan	<1 mi
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM	Phase 1/2	Tenaya Therapeutics	<1 mi
US Benchmarking Clinical Study	—	eMyosound SAS	<1 mi
Molecular Imaging of Primary Amyloid Cardiomyopathy	N/A	Brigham and Women's Hospital	<1 mi
Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Change in Cardiovascular Health	N/A	Massachusetts General Hospital	<1 mi
A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation	N/A	Boston Scientific Corporation	<1 mi
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections	Phase 3	X4 Pharmaceuticals	<1 mi
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)	Phase 3	Intellia Therapeutics	<1 mi
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)	N/A	Biosense Webster, Inc.	<1 mi
A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System	N/A	Vectorious Medical Technologies Ltd.	<1 mi
Medtronic Terminate AF Study	N/A	Medtronic Cardiac Surgery	<1 mi
Clinical Course Of Disease In Participants With FA-CM	—	Lexeo Therapeutics	<1 mi
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants	N/A	Nationwide Children's Hospital	<1 mi
The HALT Biomarker Study	Phase 1	Massachusetts General Hospital	<1 mi
PKP2-ACM Natural History Study	—	Rocket Pharmaceuticals Inc.	<1 mi
CTSN Embolic Protection Trial	N/A	Icahn School of Medicine at Mount Sinai	<1 mi
Assessment of Microvascular Circulation in the Pediatric Cardiac Surgery Patient	—	Boston Children's Hospital	<1 mi
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy	Phase 3	Alnylam Pharmaceuticals	<1 mi
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)	Phase 3	Anthos Therapeutics, Inc.	<1 mi
Assessment of CCM in HF With Higher Ejection Fraction	N/A	Impulse Dynamics	<1 mi
OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels	—	Inova Health Care Services	<1 mi
Identification of Genomic Predictors of Adverse Events After Cardiac Surgery	—	Brigham and Women's Hospital	<1 mi
Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy	N/A	Rush University Medical Center	<1 mi
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction	Phase 3	Bayer	<1 mi
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System	N/A	Aria CV, Inc	<1 mi
Cardiogenic Shock Working Group Registry	—	Tufts Medical Center	<1 mi
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment	N/A	XSpline S.p.A.	<1 mi
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities	Phase 3	Weill Medical College of Cornell University	<1 mi
Quality of Pediatric Resuscitation in a Multicenter Collaborative	—	Children's Hospital of Philadelphia	<1 mi
CCM OPEN HF Registry	—	Impulse Dynamics	<1 mi
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis	—	Columbia University	<1 mi
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction	—	Northwestern University	<1 mi
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women	Phase 3	Weill Medical College of Cornell University	<1 mi
A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment	Phase 2	BioMarin Pharmaceutical	<1 mi
Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF)	Phase 4	Massachusetts General Hospital	<1 mi
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study	Phase 2/3	Kardigan, Inc.	<1 mi
The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults	N/A	Boston Children's Hospital	<1 mi
Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot	N/A	Boston Children's Hospital	<1 mi
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III	N/A	Endotronix, Inc.	<1 mi
Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)	N/A	Varian, a Siemens Healthineers Company	<1 mi
Pulmonary Artery Catheter in Cardiogenic Shock Trial	N/A	Tufts Medical Center	<1 mi
Simulation Trial of Telemedical Support for Paramedics	N/A	Boston Medical Center	<1 mi
Supplemental Oxygen in Pulmonary Embolism (SO-PE)	Early 1	Massachusetts General Hospital	<1 mi
Positive Emotions Following Acute Cardiac Events	N/A	Massachusetts General Hospital	<1 mi
J-Valve Transfemoral Pivotal Study	N/A	JC Medical, Inc., an affiliate of Edwards Lifesciences LLC	<1 mi
Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study	N/A	Recross Cardio, Inc.	<1 mi
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy	Phase 3	Lexicon Pharmaceuticals	<1 mi
TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)	—	Brigham and Women's Hospital	<1 mi
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease	—	Children's Hospital Medical Center, Cincinnati	<1 mi
Improving Coronary Vascular Health in Women	Phase 2	Massachusetts General Hospital	<1 mi
Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure	N/A	McMaster University	<1 mi
Left Bundle Branch Area Mapping for Conduction System Pacing	—	Steward St. Elizabeth's Medical Center of Boston, Inc.	<1 mi
Ultrasound Therapy In Cardiac Amyloidosis	Phase 4	Brigham and Women's Hospital	<1 mi
Abatacept in Immune Checkpoint Inhibitor Myocarditis	Phase 3	Massachusetts General Hospital	<1 mi
Warfarin Patient Self-management Implementation in the US Healthcare System	N/A	University of Utah	<1 mi
Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery	—	Boston Children's Hospital	<1 mi
An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis	Phase 2	Zomagen Biosciences Ltd.	<1 mi
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events	Phase 3	Amgen	<1 mi
The Effect of Mindfulness on Vascular Inflammation in Stable Coronary Disease	N/A	Massachusetts General Hospital	<1 mi
A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study	N/A	Carelon Research	<1 mi
A Clinical Trial to Study the Feasibility and Acceptability of an App to Support Pediatric Resuscitation	N/A	Beth Israel Deaconess Medical Center	<1 mi
Promoting Well-being and Health in Heart Failure	N/A	Massachusetts General Hospital	<1 mi
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™	N/A	JenaValve Technology, Inc.	<1 mi
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm	N/A	Kardion Inc	<1 mi
ELEVATE-HFpEF Clinical Study	N/A	Medtronic Cardiac Rhythm and Heart Failure	<1 mi
Hydrogen's Feasibility and Safety as a Therapy in ECPR	Phase 1	Boston Children's Hospital	<1 mi
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation	Phase 2	Regeneron Pharmaceuticals	<1 mi
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)	—	Tenaya Therapeutics	<1 mi
The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).	N/A	Mayra Guerrero	<1 mi
The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium	Phase 3	Beth Israel Deaconess Medical Center	<1 mi
The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk	Phase 4	Brigham and Women's Hospital	<1 mi
The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease	—	Brigham and Women's Hospital	<1 mi
Lumason® Infusion vs. Bolus Administrations	Phase 3	Bracco Diagnostics, Inc	<1 mi
Exercise Training in Transthyretin Cardiac Amyloidosis	N/A	Brigham and Women's Hospital	<1 mi
Purinergic Signaling and the Postmenopausal Heart	—	Beth Israel Deaconess Medical Center	<1 mi
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR	N/A	Edwards Lifesciences	<1 mi
Optimal Ventilation for Cardiac Arrest	N/A	Children's Hospital of Philadelphia	<1 mi
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction	Phase 3	Cytokinetics	<1 mi
MASA Valve Early Feasibility Study	N/A	PECA Labs	<1 mi
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products	—	Medtronic	<1 mi
Evaluation of Efficacy and Safety of THRV-1268 in Long QT Syndrome Type 2 (LQTS 2)	Phase 2/3	Thryv Therapeutics, Inc.	<1 mi
CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State	—	Beth Israel Deaconess Medical Center	<1 mi
Effects of Age, Sex and Isometric Exercise on Ventricular-Vascular Interactions During Cardiac Unloading	N/A	Tracy Baynard	<1 mi
Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis	—	Boston Children's Hospital	<1 mi
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II	N/A	Shockwave Medical, Inc.	<1 mi
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures	—	Boston Children's Hospital	<1 mi
A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure	N/A	Tufts Medical Center	<1 mi
The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study	N/A	Brigham and Women's Hospital	<1 mi
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)	Phase 1	Solid Biosciences Inc.	<1 mi
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF	Phase 2	Cytokinetics	<1 mi
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.	N/A	Medtronic Cardiovascular	<1 mi
Minima Stent System Post- Approval Study (PAS)	—	Renata Medical	<1 mi
AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention	N/A	Brigham and Women's Hospital	<1 mi
Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF	N/A	Massachusetts General Hospital	<1 mi
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)	Phase 3	Novartis Pharmaceuticals	<1 mi
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction	N/A	Edwards Lifesciences	<1 mi
Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)	N/A	Western Sydney Local Health District	<1 mi
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	—	Columbia University	<1 mi
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events	N/A	Cleerly, Inc.	<1 mi
Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine	Phase 4	Massachusetts General Hospital	<1 mi
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG	Phase 3	Icahn School of Medicine at Mount Sinai	<1 mi
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)	Phase 2	Tectonic Therapeutic	<1 mi
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)	N/A	Medtronic Cardiac Ablation Solutions	<1 mi
Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health	N/A	Massachusetts General Hospital	<1 mi
CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry	—	Universitätsklinikum Hamburg-Eppendorf	<1 mi
Imaging Histone Deacetylase in the Heart	N/A	Massachusetts General Hospital	<1 mi
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass	Phase 3	Octapharma	<1 mi
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE	—	Medtronic Cardiovascular	<1 mi
Atrial Late Gadolinium Enhancement in Patients with Repaired Congenital Heart Disease	—	Boston Children's Hospital	<1 mi
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes	Phase 4	VA Office of Research and Development	<1 mi
Product Surveillance Registry	—	Medtronic	<1 mi
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients	Phase 4	University of Rochester	<1 mi
PARTNER 3 Trial - Aortic Valve-in-Valve	N/A	Edwards Lifesciences	<1 mi
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy	Phase 2	Imbria Pharmaceuticals, Inc.	<1 mi
Cardiac Sarcoidosis Randomized Trial	Phase 3	Ottawa Heart Institute Research Corporation	<1 mi
Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure	—	Tufts Medical Center	<1 mi
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR	N/A	Cardiac Dimensions, Inc.	<1 mi
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)	Phase 2/3	Merck Sharp & Dohme LLC	<1 mi
Pulmonary Embolism and Right-to-Left Shunts	—	Tufts Medical Center	<1 mi
Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension	Phase 4	Brigham and Women's Hospital	<1 mi
Physiological Assessment of Severe Coronary Stenosis for Informing Planned PCI	—	Beth Israel Deaconess Medical Center	<1 mi
HCMR Re-Imaging Study	—	Christopher Kramer	<1 mi
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)	—	Bristol-Myers Squibb	<1 mi
Finding Links Between Hot flASHes and CardioVascular Disease	Phase 2	Massachusetts General Hospital	<1 mi
Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty	N/A	VA Office of Research and Development	<1 mi
The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.	—	Heart Rhythm Clinical and Research Solutions, LLC	<1 mi
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)	N/A	University of Michigan	<1 mi
FORWARD CAD IDE Study	N/A	Shockwave Medical, Inc.	<1 mi
Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia	Phase 2	Massachusetts General Hospital	<1 mi
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)	N/A	Fundación EPIC	<1 mi
[64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy	Phase 3	Brigham and Women's Hospital	<1 mi
An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System	N/A	HighLife SAS	<1 mi
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant	Phase 3	Eidos Therapeutics, a BridgeBio company	<1 mi
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial	N/A	Edwards Lifesciences	<1 mi
Physio-Anatomy Clinical Data Collection Study	—	Gentuity, LLC	<1 mi
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)	N/A	P+F Products + Features USA Inc.	<1 mi
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study	N/A	W.L.Gore & Associates	<1 mi
The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study	—	Brigham and Women's Hospital	<1 mi
Home Hospital for Suddenly Ill Adults	N/A	Brigham and Women's Hospital	<1 mi
Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF	N/A	Beth Israel Deaconess Medical Center	<1 mi
Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest	N/A	Massachusetts General Hospital	<1 mi
Foundational Programs to Combat Clinician Stress	N/A	Lancaster General Hospital	<1 mi
Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Congestive Heart Failure Receiving Therapy for Breast Cancer	—	National Cancer Institute (NCI)	<1 mi
Positron Emission Tomography (PET) Imaging of Thrombosis	Phase 1	Massachusetts General Hospital	<1 mi
Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome	Phase 3	Albireo, an Ipsen Company	<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy	Phase 3	Pierre Fabre Medicament	<1 mi
Diffusion MRI in Heart Failure	Early 1	Massachusetts General Hospital	1 mi
The Mycophenolate Pregnancy Registry	—	Genentech, Inc.	3 mi
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity	Phase 3	SWOG Cancer Research Network	8 mi
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives	—	Sanguine Biosciences	9 mi
Personalized Responses to Dietary Composition Trial 3	N/A	Zoe Global Limited	10 mi
The Fourth Left Atrial Appendage Occlusion Study	N/A	Hamilton Health Sciences Corporation	12 mi
The CONFORM Pivotal Trial	N/A	Conformal Medical, Inc	12 mi
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation	Phase 3	Novo Nordisk A/S	29 mi
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women	N/A	Weill Medical College of Cornell University	39 mi
Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices	N/A	Andres Schanzer	39 mi
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)	Phase 3	Boehringer Ingelheim	41 mi
Prevail Global Study	N/A	Medtronic Vascular	41 mi
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS	Phase 3	DalCor Pharmaceuticals	41 mi
Mind Your Heart-II	N/A	The Miriam Hospital	41 mi
SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation	N/A	The Miriam Hospital	41 mi
Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)	Phase 2	Merck Sharp & Dohme LLC	41 mi
Intraoperative Music Therapy in TAVR Patients	N/A	Rhode Island Hospital	41 mi
Supporting Health in Veterans With Heart Failure	N/A	Florida State University	41 mi
PULSED AF Post-Approval Study	—	Medtronic Cardiac Ablation Solutions	46 mi
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure	N/A	Boston Scientific Corporation	46 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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