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Liver Disease Clinical Trials in California

168 recruiting studies across 7 cities

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All Trials in California

Phase
Trial Phase Dist.
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASHPhase 3<1 mi
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)Phase 3<1 mi
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)Phase 3<1 mi
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver FibrosisPhase 3<1 mi
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or LymphomaPhase 3<1 mi
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASHPhase 3<1 mi
A Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta InfectionPhase 2/3<1 mi
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This ConditionPhase 2<1 mi
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRIN/A<1 mi
A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular CarcinomaPhase 2<1 mi
Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine TumorsPhase 2<1 mi
A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 CirrhosisPhase 2<1 mi
A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced CancerPhase 1<1 mi
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid TumorsPhase 1/2<1 mi
Study of Bitopertin in Participants With EPP or XLP (APOLLO)Phase 3<1 mi
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )Phase 3<1 mi
Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment<1 mi
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)Phase 2<1 mi
A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)Phase 2<1 mi
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary CancerPhase 2<1 mi
A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)Phase 1<1 mi
A Study of PF-08046054/SGN-PDL1V in Advanced Solid TumorsPhase 1<1 mi
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry<1 mi
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT TrialPhase 3<1 mi
A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)Phase 2<1 mi
The Myelin Disorders Biorepository Project<1 mi
A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular CarcinomaPhase 1/2<1 mi
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid TumorsPhase 1/2<1 mi
A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid TumorPhase 1/2<1 mi
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid TumorsPhase 1/2<1 mi
Optimizing HBV Care Cascade Among Foreign-Born in the United States (FOCUS-HBV Study)<1 mi
Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor Q702 in Combination With Pembrolizumab in Patients With Selected Advanced Solid TumorsPhase 1/2<1 mi
Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary CholangitisPhase 3<1 mi
DILIN - Prospective Study<1 mi
Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency EmphysemaPhase 2<1 mi
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United StatesPhase 2<1 mi
A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment<1 mi
CM for Patients With ALD After Liver TransplantN/A<1 mi
A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary CholangitisPhase 3<1 mi
SAMe Trial for Patients With Alcoholic CirrhosisPhase 2<1 mi
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated CirrhosisPhase 3<1 mi
Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND)Phase 3<1 mi
PiMZ Longitudinal Cohort (PiMZ Logic)<1 mi
A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment<1 mi
A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 65 Years With Alcohol-related Liver DiseasePhase 2<1 mi
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)Phase 1<1 mi
Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus InfectionPhase 2<1 mi
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs<1 mi
Genetic Collection Protocol<1 mi
Longitudinal Study of the Porphyrias<1 mi
Prescreening Study to Identify Potential Wilson Disease Participants for Gene-Editing Clinical Trial<1 mi
Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)Phase 3<1 mi
TReatment for ImmUne Mediated PathopHysiologyPhase 2<1 mi
Drug-Induced Liver Injury (DILI) Network Retrospective<1 mi
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients<1 mi
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin ProteinPhase 3<1 mi
An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC DeficiencyPhase 1/2<1 mi
A Prospective Database of Infants With Cholestasis<1 mi
Long-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US)<1 mi
Primary Sclerosing Cholangitis in Children<1 mi
Danazol for Treatment of Cytopenias in Patients With CirrhosisPhase 2<1 mi
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary CholangitisPhase 2<1 mi
National Liver Cancer Screening TrialPhase 4<1 mi
A Study to Evaluate ALN-BCAT in Patients With Hepatocellular CarcinomaPhase 1<1 mi
Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway AberrationsPhase 1<1 mi
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid TumorsPhase 1<1 mi
AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic DiseasePhase 1<1 mi
DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid TumorsPhase 2<1 mi
Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple MyelomaPhase 1<1 mi
Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic CancersPhase 1<1 mi
Virtual Reality for GI Cancer Pain to Improve Patient Reported OutcomesN/A<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and ChemotherapyPhase 3<1 mi
Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver MetastasesPhase 2<1 mi
A Study of Novel Study Interventions and Combinations in Participants With Colorectal CancerPhase 2<1 mi
First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid TumoursPhase 1/2<1 mi
Multilevel Determinants of Socioeconomic Disparities in Geographic Late-Stage Hepatocellular Carcinoma Hotspots<1 mi
A Study of MGC026 in Participants With Advanced Solid TumorsPhase 1<1 mi
SIRT With Tremelimumab and Durvalumab for Resectable HCCPhase 1<1 mi
A Longitudinal Observational Study of Patients With Nonalcoholic Steatohepatitis (NASH) and Related Conditions Across the Entire Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)<1 mi
A Trial Evaluating Brelovitug vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-4)Phase 3<1 mi
Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)Phase 2<1 mi
Metabolic Responses to Bariatric Surgery<1 mi
NeuroFLiPP: Parametric PET of Neuroinflammation in Fatty Liver DiseaseEarly 1<1 mi
Long-term Safety and Efficacy of Odevixibat in Patients With Alagille SyndromePhase 3<1 mi
National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer<1 mi
Diagnostic and Therapeutic Applications of Microarrays in Liver Transplantation<1 mi
Partner Navigation Intervention for Hepatitis C Treatment Among Young People Who Inject DrugsN/A<1 mi
A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease (IFALD).Phase 2<1 mi
ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)<1 mi
Functional Assessment in Liver Transplantation<1 mi
Androgens and NAFLD Longitudinal Cohort Study<1 mi
Angiotensin II in Liver TransplantationPhase 2/3<1 mi
Pediatric Metabolic Dysfunction-associated Steatotic Liver Disease and Food Insecurity<1 mi
Bicalutamide Therapy in Young Women With NAFLD and PCOSPhase 1<1 mi
Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic SteatohepatitisN/A<1 mi
Food Insecurity and MASLD: A Fruit and Vegetable Intervention StudyN/A<1 mi
A Multicenter Cancer Biospecimen Collection Study<1 mi
Checkpoint Inhibition In Pediatric Hepatocellular CarcinomaPhase 2<1 mi
HEalth Advocate for Liver Transplantation: Improving Transition of Care for Adolescent Liver Transplant RecipientsN/A<1 mi
Radiation Therapy for the Treatment of Metastatic Gastrointestinal CancersN/A<1 mi
HEalth Advocate for Liver Transplant - PilotN/A<1 mi
Durvalumab With/Without Tremelimumab After Palliative Hypofractionated Radiotherapy for Hepatocellular CarcinomaPhase 2<1 mi
ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular CarcinomaPhase 1/2<1 mi
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have CirrhosisPhase 3<1 mi
Early Detection of Advanced Adenomas and Colorectal Cancer<1 mi
Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab TherapyN/A<1 mi
Implementing Food Referrals for Equity and Sustained HealthPhase 2<1 mi
Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ DonorsN/A<1 mi
Study of BMN 349 Single Dose in PiZZ and PiMZ/MASH Adult ParticipantsPhase 1<1 mi
Development of 3D Multi-Parametric Ultrasound (MPUS) as a Decision Support Tool for Patients<1 mi
Cryoablation and Arterial Infusion of SD-101 in Combination with Durvalumab and TremelimumabPhase 1<1 mi
DESTINY-PANTUMOUR04<1 mi
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus InfectionPhase 1<1 mi
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)Phase 2<1 mi
A Prospective, Randomized, Open Label Trial of Two Doses of Oral BetaineN/A<1 mi
Veteran-Centered Care for Advanced Liver Disease (Vet-CALD)N/A<1 mi
Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver ImpairmentPhase 1<1 mi
RESTORE TRIAL: A Phase 2 Study Evaluating the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol-Associated Liver Disease (ALD)Phase 21 mi
Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver CirrhoticsPhase 12 mi
Congenital Muscle Disease Study of Patient and Family Reported Medical Information7 mi
Hepatitis C Tracker StudyN/A7 mi
California MEPS HubN/A8 mi
Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)8 mi
Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCCPhase 29 mi
Study to Evaluate Safety, Tolerability and Pharmacokinetics of IDB-011Phase 110 mi
Quantitative Ultrasound to Assess Steatotic Liver Disease in Children11 mi
To Test Whether Time-restricted Eating Coupled With a Healthy Diet is Beneficial in Liver Cancer PatientsN/A11 mi
A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP311 mi
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid MalignanciesPhase 111 mi
ABX196 in Combination With Nivolumab in Patients With Hepatocellular CarcinomaPhase 1/211 mi
Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)14 mi
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant DiseasePhase 214 mi
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular CarcinomaPhase 314 mi
Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic DisordersPhase 216 mi
FXR Effect on Severe Alcohol-Associated Hepatitis (FRESH) StudyPhase 216 mi
A-LiNK: Improving Outcomes in Autoimmune Liver Disease16 mi
Dose-defining Study of Tirapazamine Combined With Embolization in Liver CancerPhase 1/216 mi
REGULUS: MRI-guided Adaptive SABR for Liver CancersPhase 216 mi
Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology16 mi
Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid TumorsPhase 1/216 mi
Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid TumorsPhase 116 mi
Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y9016 mi
A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid MalignanciesPhase 116 mi
A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)Phase 2/316 mi
A Cell-free tsRNA Signature for Early Detection of Hepatocellular Carcinoma16 mi
An Exosomal miRNA-based Liquid Biopsy for ICC Detection16 mi
Exosome-derived Extrahepatic Metastasis Detection By Liquid Biopsy In Colorectal Cancer Liver Metastases16 mi
A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer16 mi
Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast CancerPhase 216 mi
T-Cell Therapy (ECT204) in Adults With Advanced HCCPhase 1/216 mi
An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer16 mi
Liquid Biopsy Using Exosomal miRNA Enables Risk Stratification of Potential Metastasis in Patients With Intrahepatic Cholangiocarcinoma.16 mi
Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin ResistanceN/A17 mi
Identification of New Serum Diagnostic Markers of Hepatocellular Carcinoma17 mi
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta VirusPhase 1/217 mi
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine RegimenPhase 319 mi
Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE TrialPhase 1/220 mi
Radioembolization Trial Utilizing Eye90 Microspheres™ for the Treatment of Hepatocellular Carcinoma (HCC)N/A20 mi
Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic CancersN/A20 mi
Combination of TATE and PD-1 Inhibitor in Liver CancerPhase 220 mi
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot TrialPhase 220 mi
Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular CarcinomaPhase 220 mi
TATE and Pembrolizumab (MK3475) in mCRC and NSCLCPhase 220 mi
Investigating HepQuant DuO Test as a Biomarker in Alcohol-related Liver Disease22 mi
Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)Phase 222 mi
The Vanguard Study: Testing a New Way to Screen for CancerN/A22 mi
A Study to Investigate Pharmacokinetics (PK) and Safety of a Single Dose of Mavorixafor in Participants With Hepatic Impairment (HI) Compared to Matched Healthy Volunteers With Normal Hepatic FunctionPhase 132 mi
Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform47 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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