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Liver Disease Clinical Trials in California

161 recruiting studies across 7 cities

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All Trials in California

Phase
Trial Phase Dist.
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASHPhase 3<1 mi
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)Phase 3<1 mi
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)Phase 3<1 mi
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver FibrosisPhase 3<1 mi
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASHPhase 3<1 mi
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This ConditionPhase 2<1 mi
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRIN/A<1 mi
Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine TumorsPhase 2<1 mi
A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 CirrhosisPhase 2<1 mi
A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced CancerPhase 1<1 mi
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid TumorsPhase 1/2<1 mi
Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment<1 mi
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)Phase 2<1 mi
Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)<1 mi
A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)Phase 2<1 mi
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary CancerPhase 2<1 mi
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry<1 mi
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT TrialPhase 3<1 mi
A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)Phase 1<1 mi
A Study of PF-08046054/SGN-PDL1V in Advanced Solid TumorsPhase 1<1 mi
The Myelin Disorders Biorepository Project<1 mi
A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)Phase 2<1 mi
A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular CarcinomaPhase 1/2<1 mi
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid TumorsPhase 1/2<1 mi
FOG-001 in Locally Advanced or Metastatic Solid TumorsPhase 1/2<1 mi
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid TumorsPhase 1/2<1 mi
A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASHPhase 3<1 mi
Long-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US)<1 mi
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs<1 mi
DILIN - Prospective Study<1 mi
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)Phase 1/2<1 mi
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin ProteinPhase 3<1 mi
Drug-Induced Liver Injury (DILI) Network Retrospective<1 mi
A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver DiseasePhase 2<1 mi
TReatment for ImmUne Mediated PathopHysiologyPhase 2<1 mi
A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary CholangitisPhase 3<1 mi
A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)Phase 2<1 mi
Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)Phase 3<1 mi
Immune Tolerance Induction After Liver TransplantationPhase 1/2<1 mi
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients<1 mi
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United StatesPhase 2<1 mi
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)Phase 3<1 mi
A Prospective Database of Infants With Cholestasis<1 mi
Danazol for Treatment of Cytopenias in Patients With CirrhosisPhase 2<1 mi
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary CholangitisPhase 2<1 mi
A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment<1 mi
PiMZ Longitudinal Cohort (PiMZ Logic)<1 mi
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated CirrhosisPhase 3<1 mi
Primary Sclerosing Cholangitis in Children<1 mi
A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASHPhase 3<1 mi
A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment<1 mi
An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC DeficiencyPhase 1/2<1 mi
Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIVPhase 1/2<1 mi
Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus InfectionPhase 2<1 mi
SAMe Trial for Patients With Alcoholic CirrhosisPhase 2<1 mi
Genetic Collection Protocol<1 mi
Longitudinal Study of the Porphyrias<1 mi
First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid TumoursPhase 1/2<1 mi
AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic DiseasePhase 1<1 mi
DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid TumorsPhase 2<1 mi
A Study to Evaluate ALN-BCAT in Patients With Hepatocellular CarcinomaPhase 1<1 mi
Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple MyelomaPhase 1<1 mi
National Liver Cancer Screening TrialPhase 4<1 mi
Virtual Reality for GI Cancer Pain to Improve Patient Reported OutcomesN/A<1 mi
A Study of Novel Study Interventions and Combinations in Participants With Colorectal CancerPhase 2<1 mi
Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver MetastasesPhase 2<1 mi
A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)Phase 1/2<1 mi
Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway AberrationsPhase 1<1 mi
SIRT With Tremelimumab and Durvalumab for Resectable HCCPhase 1<1 mi
Multilevel Determinants of Socioeconomic Disparities in Geographic Late-Stage Hepatocellular Carcinoma Hotspots<1 mi
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid TumorsPhase 1<1 mi
Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic CancersPhase 1<1 mi
A Study of MGC026 in Participants With Advanced Solid TumorsPhase 1<1 mi
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and ChemotherapyPhase 3<1 mi
A Study of ZW251 in Participants With Advanced Solid TumorsPhase 1<1 mi
A Trial Evaluating Brelovitug vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-4)Phase 3<1 mi
Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)Phase 2<1 mi
Metabolic Responses to Bariatric Surgery<1 mi
NeuroFLiPP: Parametric PET of Neuroinflammation in Fatty Liver DiseaseEarly 1<1 mi
Long-term Safety and Efficacy of Odevixibat in Patients With Alagille SyndromePhase 3<1 mi
A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIVPhase 2<1 mi
Optimizing Liver MRI Using Breath-Holding With and Without OxygenN/A<1 mi
Bicalutamide Therapy in Young Women With NAFLD and PCOSPhase 1<1 mi
Functional Assessment in Liver Transplantation<1 mi
ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)<1 mi
Partner Navigation Intervention for Hepatitis C Treatment Among Young People Who Inject DrugsN/A<1 mi
Food Insecurity and MASLD: A Fruit and Vegetable Intervention StudyN/A<1 mi
Diagnostic and Therapeutic Applications of Microarrays in Liver Transplantation<1 mi
Androgens and NAFLD Longitudinal Cohort Study<1 mi
Pediatric Metabolic Dysfunction-associated Steatotic Liver Disease and Food Insecurity<1 mi
Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic SteatohepatitisN/A<1 mi
A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease (IFALD).Phase 2<1 mi
HEalth Advocate for Liver Transplant - PilotN/A<1 mi
A Multicenter Cancer Biospecimen Collection Study<1 mi
HEalth Advocate for Liver Transplantation: Improving Transition of Care for Adolescent Liver Transplant RecipientsN/A<1 mi
ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular CarcinomaPhase 1/2<1 mi
Durvalumab With/Without Tremelimumab After Palliative Hypofractionated Radiotherapy for Hepatocellular CarcinomaPhase 2<1 mi
Checkpoint Inhibition In Pediatric Hepatocellular CarcinomaPhase 2<1 mi
Radiation Therapy for the Treatment of Metastatic Gastrointestinal CancersN/A<1 mi
177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate CancerPhase 1<1 mi
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have CirrhosisPhase 3<1 mi
Early Detection of Advanced Adenomas and Colorectal Cancer<1 mi
Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab TherapyN/A<1 mi
A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or OverweightPhase 2<1 mi
Implementing Food Referrals for Equity and Sustained HealthPhase 2<1 mi
Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ DonorsN/A<1 mi
DESTINY-PANTUMOUR04<1 mi
Cryoablation and Arterial Infusion of SD-101 in Combination With Durvalumab and TremelimumabPhase 1<1 mi
Development of 3D Multi-Parametric Ultrasound (MPUS) as a Decision Support Tool for Patients<1 mi
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus InfectionPhase 1<1 mi
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)Phase 2<1 mi
A Prospective, Randomized, Open Label Trial of Two Doses of Oral BetaineN/A<1 mi
Veteran-Centered Care for Advanced Liver Disease (Vet-CALD)N/A<1 mi
Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver ImpairmentPhase 1<1 mi
RESTORE TRIAL: A Phase 2 Study Evaluating the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol-Associated Liver Disease (ALD)Phase 21 mi
Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver CirrhoticsPhase 12 mi
Phase I Clinical Study To Evaluate Pharmacokinetic Profile, Safety, Efficacy and Immunogenicity Of Ipilimumab Biosimilar HLX13 Vs. YERVOY® (US-Sourced YERVOY®) As A First-Line Treatment For Patients With Unresectable Hepatocellular CarcinomaPhase 16 mi
Congenital Muscle Disease Study of Patient and Family Reported Medical Information7 mi
Hepatitis C Tracker StudyN/A7 mi
California MEPS HubN/A8 mi
Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCCPhase 29 mi
Quantitative Ultrasound to Assess Steatotic Liver Disease in Children11 mi
Accurate Point of Care Liver Disease Diagnostics (Phase 2)11 mi
ABX196 in Combination With Nivolumab in Patients With Hepatocellular CarcinomaPhase 1/211 mi
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid MalignanciesPhase 111 mi
A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP311 mi
To Test Whether Time-restricted Eating Coupled With a Healthy Diet is Beneficial in Liver Cancer PatientsN/A11 mi
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant DiseasePhase 214 mi
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular CarcinomaPhase 314 mi
Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic DisordersPhase 216 mi
A-LiNK: Improving Outcomes in Autoimmune Liver Disease16 mi
Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid TumorsPhase 1/216 mi
Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology16 mi
Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid TumorsPhase 116 mi
Dose-defining Study of Tirapazamine Combined With Embolization in Liver CancerPhase 1/216 mi
REGULUS: MRI-guided Adaptive SABR for Liver CancersPhase 216 mi
Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y9016 mi
A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid MalignanciesPhase 116 mi
A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)Phase 2/316 mi
Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast CancerPhase 216 mi
T-Cell Therapy (ECT204) in Adults With Advanced HCCPhase 1/216 mi
Exosome-derived Extrahepatic Metastasis Detection By Liquid Biopsy In Colorectal Cancer Liver Metastases16 mi
A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer16 mi
A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid TumorsPhase 116 mi
An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer16 mi
A Cell-free tsRNA Signature for Early Detection of Hepatocellular Carcinoma16 mi
Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin ResistanceN/A17 mi
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta VirusPhase 1/217 mi
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine RegimenPhase 319 mi
Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE TrialPhase 1/220 mi
Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCCPhase 1/220 mi
Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular CarcinomaPhase 220 mi
TATE and Pembrolizumab (MK3475) in mCRC and NSCLCPhase 220 mi
Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic CancersN/A20 mi
Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot TrialPhase 220 mi
Combination of TATE and PD-1 Inhibitor in Liver CancerPhase 220 mi
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot TrialPhase 220 mi
Investigating HepQuant DuO Test as a Biomarker in Alcohol-related Liver Disease22 mi
Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)Phase 222 mi
The Vanguard Study: Testing a New Way to Screen for CancerN/A22 mi
A Study to Investigate Pharmacokinetics (PK) and Safety of a Single Dose of Mavorixafor in Participants With Hepatic Impairment (HI) Compared to Matched Healthy Volunteers With Normal Hepatic FunctionPhase 132 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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